12,733 research outputs found
Hermite regression analysis of multi-modal count data
We discuss the modeling of count data whose empirical distribution is both multi-modal and over-dispersed, and propose the Hermite distribution with covariates introduced through the conditional mean. The model is readily estimated by maximum likelihood, and nests the Poisson model as a special case. The Hermite regression model is applied to data for the number of banking and currency crises in IMF-member countries, and is found to out-perform the Poisson and negative binomial models.Count data, multi-modal data, over-dispersion, financial crises
Reducing the bias of the maximum likelihood estimator for the Poisson regression model
We derive expressions for the first-order bias of the MLE for a Poisson regression model and show how these can be used to adjust the estimator and reduce bias without increasing MSE. The analytic results are supported by Monte Carlo simulations and three illustrative empirical applications.Poisson regression, maximum likelihood estimation, bias reduction
Efficient white noise sampling and coupling for multilevel Monte Carlo with non-nested meshes
When solving stochastic partial differential equations (SPDEs) driven by
additive spatial white noise, the efficient sampling of white noise
realizations can be challenging. Here, we present a new sampling technique that
can be used to efficiently compute white noise samples in a finite element
method and multilevel Monte Carlo (MLMC) setting. The key idea is to exploit
the finite element matrix assembly procedure and factorize each local mass
matrix independently, hence avoiding the factorization of a large matrix.
Moreover, in a MLMC framework, the white noise samples must be coupled between
subsequent levels. We show how our technique can be used to enforce this
coupling even in the case of non-nested mesh hierarchies. We demonstrate the
efficacy of our method with numerical experiments. We observe optimal
convergence rates for the finite element solution of the elliptic SPDEs of
interest in 2D and 3D and we show convergence of the sampled field covariances.
In a MLMC setting, a good coupling is enforced and the telescoping sum is
respected.Comment: 28 pages, 10 figure
Gene-knockdown in the honey bee mite Varroa destructor by a non-invasive approach : studies on a glutathione S-transferase
Peer reviewedPublisher PD
Effects of nonlinear aerodynamics and static aeroelasticity on mission performance calculations for a fighter aircraft
During conceptual design studies of advanced aircraft, the usual practice is to use linear theory to calculate the aerodynamic characteristics of candidate rigid (nonflexible) geometric external shapes. Recent developments and improvements in computational methods, especially computational fluid dynamics (CFD), provide significantly improved capability to generate detailed analysis data for the use of all disciplines involved in the evaluation of a proposed aircraft design. A multidisciplinary application of such analysis methods to calculate the effects of nonlinear aerodynamics and static aeroelasticity on the mission performance of a fighter aircraft concept is described. The aircraft configuration selected for study was defined in a previous study using linear aerodynamics and rigid geometry. The results from the previous study are used as a basis of comparison for the data generated herein. Aerodynamic characteristics are calculated using two different nonlinear theories, potential flow and rotational (Euler) flow. The aerodynamic calculations are performed in an iterative procedure with an equivalent plate structural analysis method to obtain lift and drag data for a flexible (nonrigid) aircraft. These static aeroelastic data are then used in calculating the combat and mission performance characteristics of the aircraft
Steric engineering of metal-halide perovskites with tunable optical band gaps
Owing to their high energy-conversion efficiency and inexpensive fabrication
routes, solar cells based on metal-organic halide perovskites have rapidly
gained prominence as a disruptive technology. An attractive feature of
perovskite absorbers is the possibility of tailoring their properties by
changing the elemental composition through the chemical precursors. In this
context, rational in silico design represents a powerful tool for mapping the
vast materials landscape and accelerating discovery. Here we show that the
optical band gap of metal-halide perovskites, a key design parameter for solar
cells, strongly correlates with a simple structural feature, the largest
metal-halide-metal bond angle. Using this descriptor we suggest continuous
tunability of the optical gap from the mid-infrared to the visible. Precise
band gap engineering is achieved by controlling the bond angles through the
steric size of the molecular cation. Based on these design principles we
predict novel low-gap perovskites for optimum photovoltaic efficiency, and we
demonstrate the concept of band gap modulation by synthesising and
characterising novel mixed-cation perovskites.Comment: This manuscript was submitted for publication on March 6th, 2014.
Many of the results presented in this manuscript were presented at the
International Conference on Solution processed Semiconductor Solar Cells,
held in Oxford, UK, on 10-12 September 2014. The manuscript is 37 pages long
and contains 8 figure
Transcriptome analysis of the synganglion from the honey bee mite, Varroa destructor and RNAi knockdown of neural peptide targets
Acknowledgements This work was funded by BBSRC-LINK grant # BB/J01009X/1 and Vita Europe Ltd. We are grateful to the Scottish Beekeepers Association, especially Mr Phil McAnespie in supporting this work at its inception. We acknowledge partial funding from a Genesis Faraday SPARK Award, part of a Scottish Government SEEKIT project for the early part of this work. We are grateful to Prof David Evans for his advice on Varroa destructor viruses.Peer reviewedPostprin
Mary E. Giles, The Book of Prayer of Sor Maria of Santo Domingo: A Study and Translation. Albany: State University of New York Press, 1990; Richard L. Kagan, Lucrecia\u27s Dreams: Politics and Prophecy in Sixteenth-Century Spain. University of California Press, 1990; Ronald E. Surtz, The Guitar of God: Gender. Power. and Authority in the Visionary World of Mother Juana de la Cruz 0481-1534). University of Pennsylvania Press, 1990
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