Relación entre el estado del reborde alveolar residual y las características del Conducto dentario inferior en tomografías del servicio de imagenología UCSM Arequipa 2019

La presente investigación tiene como objeto determinar la relación del estado del reborde alveolar residual con las características del conducto dentario inferior desde un enfoque tomográfico. El estudio es de tipo observacional, prospectivo, transversal, descriptivo y documental, de diseño no experimental y nivel relacional. El estado del reborde alveolar residual y las características del conducto dentario inferior fueron estudiados en unidades conducto alveolar utilizando la técnica de observación tomográfica. Se consideraron 70 unidades de estudio cuyas edades están comprendidas entre los 20 y 60 años de edad, las mismas que fueron tomadas del banco de datos del Centro de Imagenología de la Universidad Católica de Santa María Arequipa Perú. Ambas variables fueron tratadas estadísticamente mediante medidas de tendencia central y dispersión en todos sus indicadores, excepto en la forma y cortical del conducto dentario inferior, que por su naturaleza categórica requirió de medidas de frecuencia. Según el caso, las pruebas estadísticas utilizadas fueron la correlación de Pearson para variables individuales cuantitativas y el X2 de independencia para relaciones cualitativas, previa transformación de escala. Según la prueba del X2 de independencia, y considerando un margen de error de 1%, se pudo determinar que no existe relación estadística significativa entre la forma, borde del conducto dentario inferior y la altura, grosor del reborde alveolar residual, no negándose la posibilidad de una relación numérica simple. Respecto a la relación de la altura del reborde alveolar residual y la ubicación del conducto dentario inferior, se pudo determinar que no existe relación. Sin embargo, la Rho de Pearson ha demostrado la existencia de una correlación positiva débil entre el grosor del reborde alveolar residual, el diámetro y la ubicación del conducto dentario inferior; y, una relación positiva muy débil entre la altura del reborde alveolar y el diámetro del conducto dentario inferior. Consecuentemente la hipótesis de la investigación es aceptada parcialmente

Typology of the Universities Colombian and Typical of his Corporate Government, a Review from his Bylaws

The purpose of this article is to describe the types of universities that exist within the university system in Colombia as well as the most relevant characteristics in their corporate government structure composed by the Maximum Collegiate Body (MCC) and the president as the executive actor of the university organization. 83 organic bylaws of the Higher Education Institutions (IES) with university academic character were considered. Variables were analyzed related to distribution and presence in the country, action fields and academic programs, juridical nature of the institutions, quality assurance, government organs and the university president. The results show a government organ diversity differentiated by their definition and functions both in the collegiate bodies and in the personal authorities, aspects related to the found typologies. It was concluded that it is necessary to establish a common criteria to orientate the practices of a good government in the IES in the framework of their autonomy that approaches topics such as conflicts of interest, to articulate the relation between coverage and quality, that promotes qualification of the managerial teams for the university management, the encouragement of meritocracy in the processes of selection, the definition of functions in the MCC and the participation of all of the groups of interest (internal and external) of the university community.Describir los tipos de universidades que integran el sistema universitario de Colombia y las particularidades más relevantes en su estructura de gobierno corporativo, compuesta por el Máximo Cuerpo Colegiado (MCC) y el Rector o actor ejecutivo superior de la organización universitaria, es el objetivo central del trabajo. Se consideraron 83 estatutos orgánicos de las Instituciones de Educación Superior (IES) con carácter académico de universidad. Se analizaron variables relacionadas con distribución y presencia en el país, campos de acción y programas académicos, naturaleza jurídica, aseguramiento de la calidad, órganos de gobierno y el Rector. Los resultados muestran una diversidad de órganos de gobierno que se diferencian dada su definición y funciones tanto en lo colegiado como en las autoridades personales, aspectos que se relacionan con las tipologías encontradas. Se concluye que urge establecer un criterio común capaz de orientar las prácticas de un buen gobierno en las IES en el marco de su autonomía, que aborde los conflictos de interés, que articule la relación de cobertura y calidad, que promueva la cualificación de los equipos gerenciales para la gestión universitaria, el fomento de la meritocracia en los procesos de selección, la definición de funciones en los MCC y la participación de todos los grupos de interés, internos y externos, de la comunidad universitaria

Fulminant Nonocclusive Mesenteric Ischemia Just after Hip Arthroplasty

Nonocclusive mesenteric ischemia (NOMI) is not a rare clinical entity in intensive medicine, and it can be a consequence of several clinical or surgical situations. This pathology results from reduced intestinal microvascular blood supply associated with an acute inflammatory process, culminating with bowel necrosis. This is a case on a female patient who developed immediate postsurgical NOMI following hip arthroplasty and died. Since diagnosis of this potentially fatal condition remains a dilemma, NOMI should always be considered an eventual postoperative complication in high-risk surgical patients such as elderly individuals with previous history of nicotine abuse, congestive heart failure, and essential hypertension. The present paper highlights the importance of early diagnosis and prompt adequate treatment of NOMI in subjects with diminished cardiac output and severe abdominal pain

Mitochondrial Oxidative Stress and Calcium-Dependent Permeability Transition are Key Players in the Mechanisms of Statins-Associated Side Effects

Statins are cholesterol-lowering medicines utilized worldwide and are associated with reduced risk of cardiovascular mortality and events. However, 0.5–10% of patients suffer from adverse effects especially on skeletal muscle. Recently, new onset of diabetes has been reported in subjects on statin therapy. Pro- and anti-oxidant effects of statins have been reported, thus fostering a debate. Previously reported data provide evidence that statins induce alterations in intracellular calcium homeostasis and mitochondrial dysfunctions that can be counteracted by antioxidants (e.g., CoQ10, creatine, and L-carnitine). Therefore, we have proposed that statin-induced inhibition of mitochondrial respiration leads to oxidative stress that opens a calcium-dependent permeability transition pore, an event that may lead to cell death. In addition, mitochondrial oxidative stress caused by statin treatment may be a signal for cellular antioxidant system responses such as catalase upregulation, possibly explaining the alleged statins’ antioxidant properties. Muscle mitochondrial dysfunction induced by statin treatment may be associated with the peripheral insulin resistance and may explain statins-induced new onset of diabetes. Together, the data presented in this review suggest that the statins’ detrimental effects can be prevented by co-administration of antioxidants

Interstitial Lung Disease in a Patient Treated with Denosumab

Denosumab is an antiresorptive agent widely used for treating osteoporosis. Atypical femur fractures, osteonecrosis of the jaw and hypocalcaemia are well-known possible adverse effects of this drug. We present, to our knowledge, the first case report in the English literature of clinically significant interstitial lung disease likely related to denosumab

Determinación de la corrosividad de crudos pesados a alta temperatura sobre un acero ferritico bajo condiciones de agitación

Los crudos pesados contienen un alto porcentaje de ácidos orgánicos, azufre y otros elementos, que a altas temperaturas y altas velocidades de flujo pueden resultar corrosivos en hornos, torres y líneas de transferencia de unidades de destilación. En este trabajo se evaluó el efecto corrosivo de dos crudos pesados con diferente TAN (número de acidez total), a tres temperaturas diferentes, manteniendo una velocidad de agitación constante. Las pruebas se desarrollaron en un autoclave dinámico adecuado para alta temperatura, utilizando las técnicas de análisis gravimétrico para evaluar la velocidad de corrosión

High frequencies of telomeric associations, chromosome aberrations, and sister chromatid exchanges in ulcerative colitis

Chromosome instability provides a predisposing background to malignancy, contributing to the crucial genetic changes in multistep carcinogenesis. The aim of this work was to analyze chromosome instability in patients with ulcerative colitis (UC) to achieve a better understanding of the increased risk for colorectal cancer. METHODS: Peripheral blood lymphocyte cultures from 20 untreated UC patients and 24 controls were used to study chromosome instability by assessing telomeric associations (TAS), chromosome aberrations (CA), and sister chromatid exchanges (SCE). RESULTS: Mean frequencies of TAS and CA were significantly increased in UC patients compared to controls (p < 0.001). Chromosomes 10, 11, 21, 16, and 19 were the most frequently involved in TAS. A total of 104 CA clustered in 66 breakpoints could be exactly localized. Seven nonrandom bands significantly affected in UC patients were found (p < 0.004), showing a significant correlation with the location of cancer breakpoints (p < 0.003), particularly with colorectal carcinoma rearrangements. SCE analysis showed higher levels in patients compared to controls (p < 0.006), but no differences were observed in cell cycle kinetics. CONCLUSIONS: Our results demonstrate the presence of an unstable genome in UC patients that could be related to the cancer development observed in this disease.Fil: Cottliar, Alejandra. Academia Nacional de Medicina de Buenos Aires. Instituto de Investigaciones Hematológicas "Mariano R. Castex"; ArgentinaFil: Fundia, Ariela Freya. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Academia Nacional de Medicina de Buenos Aires. Instituto de Investigaciones Hematológicas "Mariano R. Castex"; ArgentinaFil: Boerr, Luis. Hospital de Gastroenterología “Bonorino Udaondo,; ArgentinaFil: Sambuelli, Alicia. Hospital de Gastroenterología “Bonorino Udaondo,; ArgentinaFil: Negreira, Silvia. Hospital de Gastroenterología “Bonorino Udaondo,; ArgentinaFil: Gil, Anibal. Hospital de Gastroenterología “Bonorino Udaondo,; ArgentinaFil: Gomez, Juan Carlos. Provincia de Buenos Aires. Hospital Interzonal General de Agudos Gral. San Martin; ArgentinaFil: Chopita, Nestor. Provincia de Buenos Aires. Hospital Interzonal General de Agudos Gral. San Martin; ArgentinaFil: Bernedo, Alberto. Provincia de Buenos Aires. Hospital Interzonal General de Agudos Gral. San Martin; ArgentinaFil: Slavutsky, Irma Rosa. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Academia Nacional de Medicina de Buenos Aires. Instituto de Investigaciones Hematológicas "Mariano R. Castex"; Argentin

Application of vine-shoot chips during winemaking and aging of Malbec and Bonarda wines

The growing demand in recent years for sustainable wine production has led to the management of waste and by-products. Among them, vine-shoots could be used as additives comparable to the oak fragments widely employed in enology. This work analyzes the feasibility of applying vine-shoot chips during winemaking and the aging of Malbec and Bonarda wines from Mendoza (Argentina) and evaluates their chemical and sensory impact. Toasted (CHT) and untoasted (CHWT) vine-shoot chips obtained from a Bonarda vineyard were added in Malbec and Bonarda grapes during winemaking (Experiment A): C, control; CHWT, 12 g/L; CHT, 12 g/L. Furthermore, the same treatments were applied during aging (1M, 30 days; 2M, 60 days; 4M, 120 days) to the finished wines under controlled conditions (Experiment B). The impact of vine-shoot chips during winemaking was different between varieties. For Malbec alone, CHT caused a significant decrease in tannins, anthocyanins, and polymeric pigments, and a modification of wine color. During aging, CHWT and CHT had an impact mainly at the sensory level, increasing the wine’s complexity in terms of aromatic attributes and mouthfeel. In conclusion, the proposed technology could be a simple and economical tool for red wine production of high chemical and organoleptic qualityEEA MendozaFil: Fanzone, Martin Leandro. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Mendoza; ArgentinaFil: Catania, Anibal Alejandro. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Mendoza; ArgentinaFil: Assof, Mariela Vanesa.Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Mendoza; ArgentinaFil: Jofre, Viviana Patricia. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Mendoza; ArgentinaFil: Prieto, Jorge Alejandro. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Mendoza; ArgentinaFil: Gil Quiroga, Daniela. Universidad Juan Agustín Maza. Centro de Estudios Vitivinícolas y Agroindustriales; ArgentinaFil: Lacognata Sottano, Juan. Universidad Juan Agustín Maza. Centro de Estudios Vitivinícolas y Agroindustriales; Argentin

Causa excepcional de quilotórax: rotura espontánea de conducto torácico

The most common cause of chylothorax is a traumatic rupture of the thoracic duct due to injury or sudden increases in intrathoracic pressure or surgery, being extremely rare spontaneous rupture. Other non-traumatic causes of chylothorax may be of malignant origin (such as neoplasms of various extirpations) or non-malignant (including vena cava syndrome, systemic connective tissue diseases of immunological origin, infectious diseases, thrombosis, radiation, or aortic aneurysm).We present a case of sudden onset cervical swelling with associated chylothorax and chyloascitis, eventually diagnosed as a spontaneous rupture of the thoracic duct.La causa más frecuente de quilotórax es la rotura traumática del conducto torácico por heridas o aumentos bruscos de presión intratorácica o por cirugías, siendo la rotura espontánea extremadamente excepcional. Otras causas de quilotórax no traumáticas pueden ser de origen maligno (como las neoplasias de distintas extirpe) o no malignas (entre ellas: el síndrome de vena cava, enfermedades sistémicas de origen inmunológico del tejido conectivo, enfermedades infecciosas, trombosis, radiación o la aneurisma aorta).Describimos el caso de una paciente con una tumefacción cervical de aparición brusca con quilotórax y quiloascitis asociados, que finalmente se diagnosticó como rotura espontánea de conducto torácico