BPS states of D=4 N=1 supersymmetry

We find the combinations of momentum and domain-wall charges corresponding to BPS states preserving 1/4, 1/2 or 3/4 of D=4 N=1 supersymmetry, and we show how the supersymmetry algebra implies their stability. These states form the boundary of the convex cone associated with the Jordan algebra of $4\times 4$ real symmetric matrices, and we explore some implications of the associated geometry. For the Wess-Zumino model we derive the conditions for preservation of 1/4 supersymmetry when one of two parallel domain-walls is rotated and in addition show that this model does not admit any classical configurations with 3/4 supersymmetry. Our analysis also provides information about BPS states of N=1 D=4 anti-de Sitter supersymmetry.Comment: Latex, 27 pages. Various corrections and improvements including an expanded discussion on BPS states in ad

The fetal cerebroplacental ratio in pregnancies complicated by gestational diabetes mellitus

To assess the relationship between the cerebroplacental ratio (CPR) and intrapartum and perinatal outcomes in pregnancies complicated by gestational diabetes mellitus (GDM).This was a retrospective cohort study of women with a non-anomalous singleton pregnancy diagnosed with GDM who delivered at Mater Mothers' Hospital between 2007 and 2015. CPR was measured in 1089 cases between 34 + 0 and 36 + 6 weeks' gestation. CPR values were compared between groups categorized according to GDM treatment (by diet, oral hypoglycemic agent (OHA) or insulin). The association between CPR and intrapartum and perinatal outcomes was evaluated.No difference in CPR was observed between treatment groups. Fetuses with CPR < 10 centile were significantly more likely to have adverse composite perinatal outcome (odds ratio (OR) = 2.93 (95% CI, 1.95-4.40)), preterm delivery and low birth weight than fetuses with CPR ≥ 10 centile (all P < 0.001). These associations were present regardless of the type of GDM treatment. Fetuses of women with insulin-controlled GDM had poorer neonatal outcomes than did fetuses of women treated with OHA or dietary control alone. The risk of adverse outcome was significantly increased in the insulin-treated group (OR = 1.75 (95% CI, 1.34-2.28); P < 0.001), which also had higher rates of preterm delivery and higher birth weight.Regardless of the type of treatment, a low CPR is associated with poorer neonatal outcome in women with GDM. Copyright © 2016 ISUOG. Published by John Wiley & Sons Ltd

Aspiring Counselors’ Mental Health: Recognizing Students’ Wellbeing as an Impactor on Development

Aspiring Counselors (AC) are learning to navigate professional knowledge and skills while engaging in developmentally necessary self-reflection. Wellness, as a professional cornerstone, has been an emphasis in the instruction and development of AC. AC’s development can have barriers of professional and personal disposition, such as un-met or underattended mental health concerns which may require remediation. AC may also have higher prevalence of adverse childhood and trauma experiences. Exploring the current literature on AC’s development, wellness, and adverse childhood experiences and trauma provides insights in how counselor educators can structure programs in a more proactive rather than responsive way. The purpose of this manuscript is to explore AC’s development, wellness, gatekeeping and remediation, and adverse childhood experiences or trauma

Market tremors: shale gas exploration, earthquakes, and their impact on house prices

Shale gas has grown to become a major new source of energy in countries around the globe. While its importance for energy supply is well recognized, there has also been public concern over potential risks from hydraulic fracturing (‘fracking’). Although commercial development has not yet taken place in the UK, licenses for drilling were issued in 2008, signalling potential future development. This paper examines whether public fears about fracking affect house prices in areas that have been licensed for shale gas exploration. Our estimates suggest differentiated effects. Licensing did not affect house prices but fracking the first well in 2011, which caused two minor earthquakes, did. We find a 3.9–4.7 percent house price decrease in the area where the earthquakes occurred. The earthquakes were too minor to have caused any damage but we find the effect on prices extends to a radius of about 25 km served by local newspapers. This evidence suggests that the earthquakes and newspaper coverage increased awareness of exploration activity and fear of the local consequences

Aspiring Counselors’ Mental Health: Recognizing Students’ Wellbeing as an Impactor on Development

Aspiring Counselors (AC) are learning to navigate professional knowledge and skills while engaging in developmentally necessary self-reflection. Wellness, as a professional cornerstone, has been an emphasis in the instruction and development of AC. AC’s development can have barriers of professional and personal disposition, such as un-met or underattended mental health concerns which may require remediation. AC may also have higher prevalence of adverse childhood and trauma experiences. Exploring the current literature on AC’s development, wellness, and adverse childhood experiences and trauma provides insights in how counselor educators can structure programs in a more proactive rather than responsive way. The purpose of this manuscript is to explore AC’s development, wellness, gatekeeping and remediation, and adverse childhood experiences or trauma

Author response: Effects of orthostatic hypotension on cognition in Parkinson disease

OBJECTIVE: To investigate the relation between orthostatic hypotension (OH) and posture-mediated cognitive impairment in persons with Parkinson's disease (PD) without dementia. METHODS: There were 55 participants: 37 non-demented individuals with idiopathic PD, including 18 with OH (PDOH), and 19 without (PDWOH), and18 control participants (C). All participants completed neuropsychological tests in the supine and in the upright tilted position. Blood pressure was assessed in each posture using a standardized oscillometric cuff at the right brachial artery. RESULTS: The two PD groups performed similarly while supine, with a profile notable for executive dysfunction consisting of deficits in sustained attention, response inhibition, and semantic verbal fluency, as well as reduced verbal memory encoding and retention. When upright, these deficits were exacerbated and broadened to include additional cognitive functions in the PDOH group: deficits in phonemic verbal fluency, psychomotor speed, and both basic and complex aspects of auditory working memory. When group-specific supine scores were used as baseline anchors, both PD groups showed cognitive changes following tilt, though the PDOH group had a wider range of deficits in the executive functioning and memory domains and was the only group to show significant changes in visuospatial skills. CONCLUSIONS: Cognitive deficits in idiopathic PD have been widely reported, though assessments are typically performed in the supine position. While both PD groups had supine deficits that aligned with prior studies and clinical findings, we demonstrated that those with PD and orthostatic hypotension had transient, posture-mediated changes in excess of those found in PD without autonomic failure. These observed changes suggest an acute, reversible effect, and as orthostatic hypotension is a significant comorbid factor in PD, an independent target for clinical intervention. Further understanding of the effects of autonomic failure on cognition in other disorders is desirable, particularly in the context of neuroimaging studies and clinical assessments where data are collected only in the supine or seated positions. Identification of a distinct neuropsychological profile in PD with autonomic failure also has implications for functional activities of daily living and overall quality of life.Accepted manuscrip

Effects of orthostatic hypotension on cognition in Parkinson's disease

OBJECTIVE: To investigate the relation between orthostatic hypotension (OH) and posture-mediated cognitive impairment in Parkinson disease (PD) using a cross-sectional and within-group design. METHODS: Individuals without dementia with idiopathic PD included 18 with OH (PDOH) and 19 without OH; 18 control participants were also included. Neuropsychological tests were conducted in supine and upright-tilted positions. Blood pressure was assessed in each posture. RESULTS: The PD groups performed similarly while supine, demonstrating executive dysfunction in sustained attention and response inhibition, and reduced semantic fluency and verbal memory (encoding and retention). Upright posture exacerbated and broadened these deficits in the PDOH group to include phonemic fluency, psychomotor speed, and auditory working memory. When group-specific supine scores were used as baseline anchors, both PD groups showed cognitive changes following tilt, with the PDOH group exhibiting a wider range of deficits in executive function and memory as well as significant changes in visuospatial function. CONCLUSIONS: Cognitive deficits in PD have been widely reported with assessments performed in the supine position, as seen in both our PD groups. Here we demonstrated that those with PDOH had transient, posture-mediated changes in excess of those found in PD without OH. These observed changes suggest an acute, reversible effect. Understanding the effects of OH due to autonomic failure on cognition is desirable, particularly as neuroimaging and clinical assessments collect data only in the supine or seated positions. Identification of a distinct neuropsychological profile in PD with OH has quality of life implications, and OH presents itself as a possible target for intervention in cognitive disturbance.Accepted manuscriptAccepted manuscrip

A Human Model of Small Fiber Neuropathy to Study Wound Healing

The aim of this study was to develop a human model of acute wound healing that isolated the effects of small fiber neuropathy on the healing process. Twenty-five healthy subjects had the transient receptor vanilloid 1 agonist capsaicin and placebo creams topically applied to contralateral areas on the skin of the thigh for 48 hours. Subjects had shallow (1.2 millimeter) and deep (>3 millimeter) punch skin biopsies from each thigh on days 1 and 14. Biopsy wound healing was monitored photographically until closure. Intra-epidermal and sweat-gland nerve fiber densities were measured for each biopsy. Shallow wounds in capsaicin-treated sites healed more slowly than in placebo treated skin with biopsies taken on day 1 (P<0.001) and day 14 (P<0.001). Deep biopsies in the capsaicin and placebo areas healed at similar rates at both time points. Nerve fiber densities were reduced only in capsaicin treated regions (P<0.01). In conclusion, topical application of capsaicin causes a small fiber neuropathy and is associated with a delay in healing of shallow, but not deep wounds. This novel human model may prove valuable in the study of wound healing in patients with neuropathy

Concentration of Adenoviruses and Noroviruses from Seawater with Argonide Nanoceram Cartridge Filters: Method Effectiveness and Occurrence in Southern California Recreational Waters

The goals of this study were to evaluate Argonide Nanoceram cartridge filters for concentrating adenoviruses and noroviruses from seawater and then apply them to Southern California recreational water samples. The filters were challenged with 20-40 L of seawater seeded with test viruses; the recoveries of adenoviruses and noroviruses were 3.2% (± 2.3%) and 111% (± 28%), respectively. PEG precipitation was used as a secondary concentration step, and recovery rates with optimized conditions were 34% (± 12%) for adenovirus, and 59% (± 4.8%) for norovirus. These methods were applied to seawater samples from two Southern California beaches for the detection of both viruses. For Doheny Beach, 24 and 21 of 93 samples were positive for adenovirus and norovirus, respectively. For Avalon Beach, 26 and 2 of 286 samples were positive for adenovirus and norovirus, respectively. The presence of enteric viruses was not associated with the presence of coliphages in this study.Master of Scienc