415 research outputs found

    Insights into the Dynamics of the Human Zinc Transporter ZnT8 by MD Simulations

    Get PDF

    Foldy-Wouthuysen Transformation for a Spinning Particle with Anomalous Magnetic Moment

    Full text link
    We study the Foldy-Wouthuysen transformation for a pseudoclassical particle with anomalous magnetic moment in an external, stationary electromagnetic field. We show that the transformation can be expressed in a closed form for neutral particles in purely electrostatic fields and for neutral and charged particles in external magnetostatic fields. The explicit expressions of the diagonalized Hamiltonians are calculated.Comment: 10 page

    Spinning particle in an external linearized gravitational wave field

    Full text link
    We study the interaction of a scalar and a spinning particle with a coherent linearized gravitational wave field treated as a classical spin two external field. The spin degrees of freedom of the spinning particle are described by skew-commuting variables. We derive the explicit expressions for the eigenfunctions and the Green's functions of the theory. The discussion is exact within the approximation of neglecting radiative corrections and we prove that the result is completely determined by the semiclassical contribution.Comment: 11 page

    Adhesion to zirconia: A systematic review of current conditioning methods and bonding materials

    Get PDF
    Background. Reliable bonding between resin composite cements and high strength ceramics is difficult to achieve because of their chemical inertness and lack of silica content that makes etching impossible. The purpose of this review is to classify and analyze the existing methods and materials suggested to improve the adhesion of zirconia to dental substrate by using composite resins, in order to explore current trends in surface conditioning methods with predictable results. Methods. The current literature, examining the bond strength of zirconia ceramics, and including in vitro studies, clinical studies, and a systematic review, was analyzed. The research in the literature was carried out using PubMed and Cochrane Library databases, only papers in English, published online from 2013 to 2018. The following keywords and their combinations were used: Zirconia, 3Y-TZP, Adhesion, Adhesive cementation, Bonding, Resin, Composite resin, Composite material, Dentin, Enamel. Results. Research, in PubMed and Cochrane Library databases, provided 390 titles with abstracts. From these, a total of 93 publications were chosen for analysis. After a full text evaluation, seven articles were discarded. Therefore, the final sample was 86, including in vitro, clinical studies, and one systematic review. Various adhesive techniques with different testing methods were examined. Conclusions. Airborne-particle abrasion and tribo-chemical silica coating are the pre-treatment methods with more evidence in the literature. Increased adhesion could be expected after physico-chemical conditioning of zirconia. Surface contamination has a negative effect on adhesion. There is no evidence to support a universal adhesion protocol

    Optimization of extraction of drugs containing polyphenols using an innovative technique

    Get PDF
    The role of polyphenols in human health nowadays is well established and these natural products, found in many plant species, are the active ingredients of drugs, food supplements and cosmetics. Extraction procedure is pivotal to obtain high quality herbal products but paradoxically this factor is often underrated and obsolete techniques are used. In this work we compared the classic and most used method of maceration and an innovative and standardized technique of extraction, Estrattore Naviglio((R)), processing ten common medicinal plants containing polyphenols and for each analysing specific biological markers such as flavonoids, anthocyanosides and caffeic derivatives in addition to total polyphenols content. Estrattore Naviglio((R)) guaranteed a significant improvement of the chemical quality of extracts combining effectiveness with rapidity and reproducibility. In this work we further investigated the optimization of drug extractions by replicating operations varying parameters setting on Estrattore Naviglio((R)) instrument

    Local Variational Principle

    Full text link
    A generalization of the Gibbs-Bogoliubov-Feynman inequality for spinless particles is proven and then illustrated for the simple model of a symmetric double-well quartic potential. The method gives a pointwise lower bound for the finite-temperature density matrix and it can be systematically improved by the Trotter composition rule. It is also shown to produce groundstate energies better than the ones given by the Rayleigh-Ritz principle as applied to the groundstate eigenfunctions of the reference potentials. Based on this observation, it is argued that the Local Variational Principle performs better than the equivalent methods based on the centroid path idea and on the Gibbs-Bogoliubov-Feynman variational principle, especially in the range of low temperatures.Comment: 15 pages, 5 figures, one more section adde

    Quantum Double and Differential Calculi

    Full text link
    We show that bicovariant bimodules as defined by Woronowicz are in one to one correspondence with the Drinfeld quantum double representations. We then prove that a differential calculus associated to a bicovariant bimodule of dimension n is connected to the existence of a particular (n+1)--dimensional representation of the double. An example of bicovariant differential calculus on the non quasitriangular quantum group E_q(2) is developed. The construction is studied in terms of Hochschild cohomology and a correspondence between differential calculi and 1-cocycles is proved. Some differences of calculi on quantum and finite groups with respect to Lie groups are stressed.Comment: Revised version with added cohomological analysis. 14 pages, plain te

    Two fermion relativistic bound states: hyperfine shifts

    Full text link
    We discuss the hyperfine shifts of the Positronium levels in a relativistic framework, starting from a two fermion wave equation where, in addition to the Coulomb potential, the magnetic interaction between spins is described by a Breit term. We write the system of four first order differential equations describing this model. We discuss its mathematical features, mainly in relation to possible singularities that may appear at finite values of the radial coordinate. We solve the boundary value problems both in the singular and non singular cases and we develop a perturbation scheme, well suited for numerical computations, that allows to calculate the hyperfine shifts for any level, according to well established physical arguments that the Breit term must be treated at the first perturbative order. We discuss our results, comparing them with the corresponding values obtained from semi-classical expansions.Comment: 16 page

    Protection against oxidative damage of erythrocyte membrane by the flavonoid quercetin and its relation to iron chelating activity

    Get PDF
    AbstractIncubation of glutathione (GSH) depleted mouse erythrocytes with the oxidants phenylhydrazine, acrolein, divicine and isouramil resulted in the release of free iron and in lipid peroxidation and hemolysis. The addition of the flavonoid quercetin, which chelates iron and penetrates erythrocytes, resulted in remarkable protection against lipid peroxidation and hemolysis. The protection seems to be due to intracellular chelation of iron, since a semi-stoichiometric ratio between released iron and the amount of quercetin necessary to prevent lipid peroxidation and hemolysis was found. Incubation of GSH depleted human erythrocytes with divicine and isouramil did not induce lipid peroxidation and hemolysis in spite of a substantial release of iron. However, divicine and isouramil produced alterations of membrane proteins, such as spectrin and band 3, as well as formation of senescent cell antigen. The addition of quercetin prevented these alterations
    • …
    corecore