38 research outputs found
Identification of several forms of the glial fibrillary acidic protein, or alpha-albumin, by a specific monoclonal-antibody
No full textImmunocytochemical detection of the growth-associated protein B-50 by newly characterized monoclonal antibodies in human brain and muscle
No full textSocial impact on Alzheimer's disease families co-operating in a scientific research programme
No full textMultiple sclerosis and magnetic resonance imaging: a follow-up study using extensive standardized non-contrast enhanced MRI procedures
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Long term follow-up of multiple sclerosis by standardized, non-contrast-enhanced magnetic resonance imaging
No full textAntibody-Mediated Modification of Encephalitis Induced by Hamster Neurotropic Measles Virus
No full textThe acute encephalopathy induced by hamster neurotropic (HNT) measles virus in BALB/c mice was abolished, and a subacute encephalitis was induced instead, when antibody to Edmonston (Ed) measles virus was administered three days after inoculation of HNT virus. Ascites fluid from 79XICl, a monocolonal antibody to the hemagglutinin of strain Ed, had similar effects in vivo. However, other monoclonal antibodies to the hemagglutinin of Ed strain-79XVV17 and 80IIIB2-were ineffective in vivo at all doses tested. By viral neutralization, immunofluorescence, and radioimmunoprecipitation assays, it was shown that the hemagglutinin of HNT virus reacted with 79XICl antibody but lacked the epitopes recognized by 79XVV17 or 80IIIB2 antibody, a finding that explains their different reactivity in vivo. These observations also identified previously unrecognized antigenic differences between the hemagglutinin of Ed and HNT measles viruses
