4 research outputs found
Economic impact of interventional study on rational use of antiseptics and disinfectants in Super Speciality Hospital of Nagpur
Objective: To measure the impact of interventions on rational use of
antiseptics and disinfectants (A and D) for cost containment in Super
Speciality Hospital (SSH) of Government Medical College, Nagpur (GMCN),
India. Materials and Methods: This study was conducted from October
2003 to March 2007 in SSH of GMCN. In the pre-interventional phase
(Phase-I), purchase, stocking and distribution of A and D was studied
to find problem areas. Based on this formative data an intervention was
planned (Phase-II) during which rationing of the A and D was done.
Rational quantities needed for different A and D procedures were
calculated based on recommendations of National Aids Control
Organization (NACO) with modifications to suit our hospital setup.
Detailed information, education, communication and training about
rational use of A and D were provided to the hospital staff. In the
post-interventional phase (Phase-III), the use of A and D was
rationalized at the distribution level and the efficacy of in-use A and
D was tested at user sites. Data about medicine expenditure, patient
record and A and D usage in various departments was obtained from
hospital records. Savings on A and D as against total annual medicine
expenditure was calculated taking the cost of A and D in the
post-intervention period. Results: The expenditure on A and D as a
result of intervention decreased by 20.7%. Out of the total medicine
expenditure, the expenditure on A and D which accounted for 6.2% before
intervention, decreased to 1.95% after the intervention. Conclusion:
The information, education and communication (IEC) interventions
attempted by us resulted in significant decrease in the use and
expenditure of A and D
Effect of information, education and communication intervention on awareness about rational pharmacy practice in pharmacy students
Background: There is a growing indifference among the pharmacy
practitioners towards their duty as information providers to the
patients. The patients do not always get enough desired information
about proper use of medicines from the prescribers also. This
contributes to improper use of medicines by the patients. Objectives:
To bring about awareness about rational pharmacy practice in pharmacy
students for better service to the patients. Material and Methods: The
final year students of Bachelor of Pharmacy (B. Pharm) from four
colleges of Nagpur were enrolled for the study after informed consent.
Their base knowledge was assessed through a written test which
comprised of 27 objective questions related to rational pharmacy
practice. This was followed by a series of seven articles on rational
medicine use, published in leading local English news daily. The
participants were reminded to read them on the day of publication of
each article. As a backup, the articles were displayed on the notice
board of respective colleges. Second intervention was a half day
interactive session where series of six lectures were delivered to the
participants on the right and wrong approaches in pharmacy practice.
Posters about the do′s and dont′s of rational pharmacy
practice were also displayed at the venue. The session was followed by
a repeat test using the same pre-test to assess the change. Pre and
post intervention data was compared using Fisher′s Exact test.
Results: It was observed that the intervention did bring about a
positive change in the attitude and knowledge of the final year
Pharmacy students about rational pharmacy practice. Discussion: The
role of a pharmacist in health care provision is usually overlooked in
India. Hence there is strong need for reinforcement in final year B.
Pharm when most of the students go in for community service. Such
interventions will be helpful in bringing about a positive change
towards rational practice of pharmacy. Conclusion: This study showed
that a properly timed and meticulously implemented intervention brings
about a positive change in the attitude and knowledge of pharmacy
students
Comparison of safety, efficacy, and cost effectiveness of benzyl benzoate, permethrin, and ivermectin in patients of scabies
Objective: To compare three treatment modalities in scabies for safety,
efficacy, and economy in a local population of Nagpur. Materials and
Methods: This was a prospective, randomized, comparative clinical trial
conducted in 103 participants, randomly allocated to three groups.
First group received benzyl benzoate (BB) 25% lotion, second group
received permethrin 5% cream, whereas third group received tablet
ivermectin 200 µg/kg as a single dose. The participants were
recalled after one week for follow-up evaluation. If there were no
signs of cure, the same intervention was repeated. The participants
were followed up for two weeks for cure rate, adverse drug reaction
(ADR) monitoring, and postintervention observation. The follow-up was
stopped after two weeks. Statistics: Fischer′s exact test using
Graph pad Instat v 3.05. Results: Ivermectin showed 100% cure rate
after two weeks of treatment. Permethrin decreased pruritus by 76% at
the end of one week and had significantly better cure rate than
ivermectin. At the end of two weeks treatment, this finding was
reversed, that is, cure rate in ivermectin group was 100%. For
cost-effectiveness analysis, treatment regimens were formulated
hypothetically for comparison from Markov population tree for decision
analysis. It was found that BB and ivermectin each consecutively for
two weeks were most cost effective regimens giving complete cure in
four weeks, while ivermectin was the fastest regimen giving the same
results in two weeks. Conclusion: Benzyl benzoate as first line
intervention and ivermectin in the remaining gave best cost-effective
results in the study patients of scabies