Synthetic, spectroscopic and Antimicrobial activity of mixed ligand of some complexes of symmetrical Schiff base and Nicotinamide

New symmetrical Schiff base ligand (H2L) is prepared via condensation of hydrazine hydrate and 4-hydroxy-3-methoxybenzaldehyde  in ethanol solution at room temperature is reported  . Polydentate  mixed ligand     complexes were obtained from 1:1:1  molar ratio reactions with metal ions and H2L, NA  on reaction with MCl2 .nH2O salt yields complexes corresponding to the formulas [M(L)(NA)2] . All the complexes are air stable and soluble in water and common organic except benzene .All complexes are soluble in dimethyl formamide (DMF)and dimethyl sulfoxide (DMSO) solvent. Comparison of the IR spectra of ligands(H2L) and  (NA)  and there  metal complexes confirm that Schiff base behave as a dibasic tetradentate ligand towards the central metal ion with an ONNO donor sequence  and nicotinamid . behave as unidentate . The ligands and their metal complexes were screened for their antimicrobial activity against four bacteria(gram +ve) and (gram -ve). Keywords: Complexes; Spectral; symmetrical Schiff base Metal complexes ; Antimicrobial activities

Synthesis, Characterization, And Antibacterial Activities Of Manganese (II), Cobalt(II), Iron (II), Nickel (II) , zinc (II) And Cadmium(II) Mixed- Ligand Complexes Containing Amino Acid(L-Valine) And Saccharin

A new six mixed ligand complexes of some transition metal ions Manganese (II), Cobalt(II), Iron (II), Nickel (II) , and non transition metal ion zinc (II) And Cadmium(II) with L-valine (Val H ) as a primary ligand and Saccharin (HSac)  as a secondary ligands  have been prepared. All the prepared complexes have been characterized by molar conductance, magnetic susceptibility infrared, electronic spectral, Elemental microanalysis (C.H.N) and AA . The complexes with the formulas   [M(Val)2(HSac)2] M= Mn (II) , Fe (II) , Co(II) ,Ni(II), Cu (II),Zn(II) and  Cd(II) L- Val H= (C5H11NO2)  , C7H5NO3S   The study shows that these complexes have octahedral geometry; The metal complexes have been screened for their in microbiological activities against bacteria.  Based on the reported results, it may be concluded that the deprotonated ligand  (L-valine) to (valinate ion (Val-)  by using (Na OH) coordinated to metal ions as bidentate ligand through the oxygen atom of the carboxylate group(-COO-), and the nitrogen atom of the amine group (NH2), where the saccharin (H Sac) coordinated as a monodentate through the nitrogen atom. Keywords: L-Valine , mixed ligand complexes, Saccharin  , spectral studies , Antibacterial activities.

Synthesis ,characterization and antibacterial activity of mixed ligand complexes of some metals with 1-nitroso-2-naphthol and L-phenylalanine

The mixed ligand complexes of Mn(II),Fe(II),Co(II),Ni(II),Cu(II), Zn(II) and Cd (II) with 1-nitroso-2-naphthol (C10H7NO2), symbolized (NNPhH)] and amino acid L-phenylalanine( C9H10NO2), symbolized (phe H),  were synthesized and characterized by: Melting points, Solubility, Molar conductivity. determination the percentage of the metal in the complexes by flame(AAS), Molecular weight determined by  Rast’s Camphor method, susceptibility measurements, Spectroscopic Method [FT-IR and UV-Vis], And Program  [Chem office– CS .Chem.– 3D pro 2006] was used for draw compounds . The results showed that the deprotonated   two  ligands acts as a bidentate ligand ,  (phe-) was coordinated to the metal ions through the oxygen  of  the  carboxylic  group  and  the nitrogen of the amine and  the 1-nitroso-2-naphthol ligand was coordinated to the metal ions through the oxygen and nitrogen atoms. The electronic absorption spectra and magnetic susceptibility measurements of the complexes indicate octahedral geometry for all the complexes. Key words: phenyl alanine , amino acid) Complexes ,  1-nitroso-2-naphthol  ,mixed ligands   and Antibacterial     Activitie