26 research outputs found
Exendin-4 impairs intestinal tissue damage through its proliferative and anti-fibrotic effects in diabetic rats
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The relation among NGF, EGF and insulin is important for triggering pancreatic beta cell apoptosis
Full text linkBackground Nerve growth factor (NGF) is a well-known mediator for maintaining the survival of neurons, while recent studies report that its absence induces apoptosis in cultured beta cells of humans and rats. However, its relationship with other growth factors that have important roles in the survival and function of beta cells such as epidermal growth factor (EGF) has not yet been elucidated. The aim of this study was to investigate the effects of NGF withdrawal on the synthesis and secretion of EGF, insulin with respect to beta cell apoptosis in hyperglycemic rats
NGF regulates EGF, NGF and insulin at the expression, synthesis and secretion levels in beta cells of rats
Full text linkThe relation between NGF and activin A is important for triggering pancreatic beta cell apoptosis
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Prostaglandin E(1) reduces renal ischemia/ reperfusion-induced gastric damage through its anti-inflammatory and anti-oxidative effects
Full text link4-Methylcatechol suppresses liver injury through blocking ROS production in the liver of hyperglycemic rats
Full text linkThe curative effects of exendin-4 on renal oxidative damage, inflammation and fibrosis in diabetic mice
Full text linkExendin-4 ameliroates renal injury by decreasing inflammation and ROS production in diabetic mice
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