Spectroscopy of Low Surface Brightness Galaxies with the Hobby-Eberly Telescope

We have obtained low resolution spectra of nineteen red and blue low surface brightness galaxies, using the Marcario Low Resolution Spectrograph on the 9.2m Hobby-Eberly Telescope. These galaxies form a very heterogeneous class, whose spectra qualitatively resemble those of high surface brightness galaxies covering the full range of spectra seen in galaxies of Hubble types from E to Irr. We use a combination of emission line (EW(Halpha), NII/Halpha) and absorption line (Mgb, Hbeta, ) based diagnostics to investigate the star-formation and chemical enrichment histories of these galaxies. These are diverse, with some galaxies having low metallicity and very young mean stellar ages, and other galaxies showing old, super-solar metallicity stellar populations. In contrast with some previous studies which found a strong trend of decreasing metallicity with decreasing central surface brightness, we find a population of galaxies with low surface brightness and near-solar metallicity. Correlations between several of the gas phase and stellar population age and metallicity indicators are used to place contraints on plausible evolutionary scenarios for LSB galaxies. The redshift range spanned by these galaxies is broad, with radial velocities from 3400 km/s to more than 65000 km/s. A subset of the sample galaxies have published HI redshifts and gas masses based on observations with the Arecibo 305m single-dish radio telescope, which place these galaxies far off of the mean Tully-Fisher relation. Our new optical redshifts do not agree with the published HI redshifts for these galaxies. Most of the discrepancies can be explained by beam confusion in the Arecibo observations, causing erroneous HI detections for some of the galaxies.Comment: 31 pages, 12 figures, 7 tables. Uses emulateapj5.sty and onecolfloat5.sty, which are included. Accepted for publication in the Astronomical Journa

Characterization of immune response to neurofilament light in experimental autoimmune encephalomyelitis

PMCID: PMC3856490This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.PMCID: PMC385649

The Baryonic Tully-Fisher Relation

We explore the Tully-Fisher relation over five decades in stellar mass in galaxies with circular velocities ranging over 30 < Vc < 300 km/s. We find a clear break in the optical Tully-Fisher relation: field galaxies with Vc < 90 km/s fall below the relation defined by brighter galaxies. These faint galaxies are however very gas rich; adding in the gas mass and plotting baryonic disk mass Md = M* + Mg in place of luminosity restores a single linear relation. The Tully-Fisher relation thus appears fundamentally to be a relation between rotation velocity and total baryonic mass of the form Md = A Vc^4.Comment: 10 pages including 1 color figure. Accepted for publication in ApJ Letter

Star formation thresholds and galaxy edges: why and where

We study global star formation thresholds in the outer parts of galaxies by investigating the stability of disk galaxies embedded in dark halos. The disks are self-gravitating, contain metals and dust, and are exposed to UV radiation. We find that the critical surface density for the existence of a cold interstellar phase depends only weakly on the parameters of the model and coincides with the empirically derived surface density threshold for star formation. Furthermore, it is shown that the drop in the thermal velocity dispersion associated with the transition from the warm to the cold gas phase triggers gravitational instability on a wide range of scales. The presence of strong turbulence does not undermine this conclusion if the disk is self-gravitating. Models based on the hypothesis that the onset of thermal instability determines the star formation threshold in the outer parts of galaxies can reproduce many observations, including the threshold radii, column densities, and the sizes of stellar disks as a function of disk scale length and mass. Finally, prescriptions are given for implementing star formation thresholds in (semi-)analytic models and three-dimensional hydrodynamical simulations of galaxy formation.Comment: 16 pages, 6 figures, accepted for publication in the Astrophysical Journal. Version 2: text significantly revised (major improvements), physics unchanged. Version 3: minor correction

The Metamorphosis of Tidally Stirred Dwarf Galaxies

We present results from high-resolution N-Body/SPH simulations of rotationally supported dwarf irregular galaxies moving on bound orbits in the massive dark matter halo of the Milky Way.The dwarf models span a range in disk surface density and the masses and sizes of their dark halos are consistent with the predictions of cold dark matter cosmogonies. We show that the strong tidal field of the Milky Way determines severe mass loss in their halos and disks and induces bar and bending instabilities that transform low surface brightness dwarfs (LSBs) into dwarf spheroidals (dSphs) and high surface brightness dwarfs (HSBs) into dwarf ellipticals (dEs) in less than 10 Gyr. The final central velocity dispersions of the remnants are in the range 8-30 km/s and their final $v/\sigma$ falls to values $< 0.5$, matching well the kinematics of early-type dwarfs. The transformation requires the orbital time of the dwarf to be \simlt 3-4 Gyr, which implies a halo as massive and extended as predicted by hierarchical models of galaxy formation to explain the origin of even the farthest dSph satellites of the Milky Way, Leo I and Leo II. Only dwarfs with central dark matter densities as high as those of Draco and Ursa Minor can survive for 10 Gyr in the proximity of the Milky Way: this is naturally achieved within hierarchical models, where the densest objects should have small orbital times due to their early formation epochs. Part of the gas is stripped and part is funneled to the center due to the bar, generating one strong burst of star formation in HSBs and smaller, multiple bursts in LSBs. Extended low-surface brightness stellar and gaseous streams originate from LSBs and, when projected along the line of sight, can lead to overestimate the mass-to-light ratio of the bound remnant by a factor \simlt 2,Comment: 29 pages, 34 figures, submitted to ApJ. Figures 5,11 and 32 are given as separate GIF files. Other figures and the movies of the simulations can be found at http://pcblu.mib.infn.it/~lucio/LG/LG.htm

The Extraordinary `Superthin' Spiral Galaxy UGC7321. I. Disk Color Gradients and Global Properties from Multiwavelength Observations

We present B- and R-band imaging and photometry, H-alpha narrow-band imaging, NIR H-band imaging, and HI 21-cm spectroscopy of the nearby Sd spiral galaxy UGC7321. UGC7321 exhibits a remarkably thin stellar disk with no bulge component. The galaxy has a very diffuse, low surface brightness disk, which appears to suffer little internal extinction in spite of its edge-on geometry. The UGC7321 disk shows significant B-R color gradients in both the radial and vertical directions. These color gradients cannot be explained solely by dust and are indicative of changes in the mix of stellar ages and/or metallicity as a function of both radius and height above the galaxy plane. The outer regions of the UGC7321 disk are too blue to be explained by low metallicity alone (B-R<0.6), and must be relatively young. However, the galaxy also contains stellar populations with B-R>1.1, indicating it is not a young or recently-formed galaxy. The disk of UGC7321 is not a simple exponential, but exhibits a light excess at small radii, as well as distinct surface brightness zones. Together the properties of UGC7321 imply that it is an under-evolved galaxy in both a dynamical and in a star-formation sense. (Abridged)Comment: Accepted to the Astronomical Journal; 28 pages, 1 table and 21 figures (GIF and postscript

Different susceptibility of osteosarcoma cell lines and primary cells to treatment with oncolytic adenovirus and doxorubicin or cisplatin

Despite improvements in treatment regimens for osteosarcoma (OS) patients, survival rate has not increased over the last two decades. New treatment modalities are therefore warranted. Preclinical results with conditionally replicative adenoviruses (CRAds) to treat OS are promising. One type of CRAd that was effective against OS cells is Ad5-Δ24RGD. In other types of cancer, CRAds have been shown to interact synergistically with chemotherapeutic agents. Chemotherapy for OS often includes doxorubicin and cisplatin. Therefore, we explored combination treatment of OS cell lines and primary OS cell cultures with Ad5-Δ24RGD and doxorubicin or cisplatin. On OS cell lines, combination treatment was additive to synergistic. Surprisingly, however, on seven of eight primary OS samples no such combination effects were observed. In contrast, in many cases chemotherapy even inhibited CRAd-mediated cell killing. The inhibitory effect of doxorubicin on Ad5-Δ24RGD in primary OS cells appeared to correlate with slow cell growth rate; reduced viral replication and absence of chemotherapy-induced G2 cell cycle arrest. Our results point to the possibility that, at least for OS, virotherapy and chemotherapy should best not be performed simultaneously. In general, our work underscores the importance of testing new genetic anticancer agents and treatment regimens on primary cancer specimens

The mass surface density in the local disk and the chemical evolution of the Galaxy

We have studied the effect of adopting different values of the total baryonic mass surface density in the local disk at the present time in a model for the chemical evolution of the Galaxy. We have compared our model results with the G-dwarf metallicity distribution, the amounts of gas, stars, stellar remnants, infall rate and SN rate in the solar vicinity, and with the radial abundance gradients and gas distribution in the disk. This comparison strongly suggests that the value of the total baryonic mass surface density in the local disk which best fits the observational properties should lie in the range 50-75 Msun pc-2, and that values outside this range should be ruled out.Comment: 6 pages, LaTeX, 3 figures, accepted for publication in the Astrophysical Journal, uses emulateapj.st

English in product advertisements in non-english speaking countries in western europe: Product image and comprehension of the text

Although English has been shown to be the most frequently used foreign language in product advertisements in countries where it is not the native language, little is known about its effects. This article examines the response to advertisements in English compared to the response to the same ad in the local language in Western Europe on members of the target group for which the ad was intended: 715 young, highly educated female consumers. The use of English in a product ad does not appear to have any impact on image and price of the product, but it does affect text comprehension: the meaning of almost 40% of the English phrases was not understood. These results were the same for all countries involved in the study, irrespective of whether the respondents\u27 (self-) reported proficiency in English is high or low. © Taylor & Francis Group, LLC

Abundance Gradients and the Formation of the Milky Way

In this paper we adopt a chemical evolution model, which is an improved version of the Chiappini, Matteucci and Gratton (1997) model, assuming two main accretion episodes for the formation of the Galaxy. The present model takes into account in more detail than previously the halo density distribution and explores the effects of a threshold density in the star formation process, during both the halo and disk phases. In the comparison between model predictions and available data, we have focused our attention on abundance gradients as well as gas, stellar and star formation rate distributions along the disk. We suggest that the mechanism for the formation of the halo leaves detectable imprints on the chemical properties of the outer regions of the disk, whereas the evolution of the halo and the inner disk are almost completely disentangled. This is due to the fact that the halo and disk densities are comparable at large Galactocentric distances and therefore the gas lost from the halo can substantially contribute to building up the outer disk. We also show that the existence of a threshold density for the star formation rate, both in the halo and disk phase, is necessary to reproduce the majority of observational data in the solar vicinity and in the whole disk. Moreover, we predict that the abundance gradients along the Galactic disk must have increased with time and that the average [alpha/Fe] ratio in stars (halo plus disk) slightly decrease going from 4 to 10 Kpcs from the Galactic center. We also show that the same ratios increase substantially towards the outermost disk regions and the expected scatter in the stellar ages decreases, because the outermost regions are dominated by halo stars.Comment: 41 pages (including the figures), To be published in Ap