Creating a New Collections Allocation Model for These Changing Times: Challenges, Opportunities, and Data

This presentation focuses on the development of a formula for potential use in allocating the collections budget for Penn State and the questions that arose during the process. The Associate Dean for Collections, Information, and Access Services charged a Collections Allocations Team to examine the development and use of a collections allocation formula. The team used a variety of methods to guide the development of the formula including a literature review, a survey of ARL Chief Collection Development Officers, and discussions with fellow selectors within the University Libraries. In addition, the Team developed other recommendations related to the allocation of the collections budget, especially focusing on the process of collection development, duplication of materials across the University Libraries, and the rewriting of collection development policies

Sobre la información de amplitud transmitida por el campo sísmico ambiental

The use of the ambient seismic field (ASF) to extract Earth’s response has received significant attention in the last several years. Multiple studies demonstrate the utility of the ASF for estimating high-resolution velocity models in various locations. In this paper, we discuss the amplitude information carried by the ASF. Amplitude information includes both amplification effects due to elastic structure, such as low velocity sedimentary basins, and attenuation effects in the crust and upper mantle or even in buildings. As has been suggested by other authors, amplitude measurements may be biased due to nonuniformities in ambient field excitation; however, we find very similar and stable results for different time intervals for both amplification and attenuation, suggesting that this bias may not be as large as feared. We conclude that valuable amplitude information can be recovered from the ASF through careful processing. Amplitude measurements may be particularly valuable due to the enhanced sensitivity of attenuation to fluids and/or temperature fluctuations. 2011 Acade´mie des sciences. Published by Elsevier Masson SAS. All rights reserve

Revisiting Maxwell-Smoluchowski theory: low surface roughness in straight channels

The Maxwell-Smoluchowski (MS) theory of gas diffusion is revisited here in the context of gas transport in straight channels in the Knudsen regime of large mean free path. This classical theory is based on a phenomenological model of gas-surface interaction that posits that a fraction $\vartheta$ of molecular collisions with the channel surface consists of diffuse collisions, i.e., the direction of post-collision velocities is distributed according to the Knudsen Cosine Law, and a fraction $1-\vartheta$ undergoes specular reflection. From this assumption one obtains the value $\mathcal{D}=\frac{2-\vartheta}{\vartheta}\mathcal{D}_K$ for the self-diffusivity constant, where $\mathcal{D}_K$ is a reference value corresponding to $\vartheta=1$. In this paper we show that $\vartheta$ can be expressed in terms of micro- and macro-geometric parameters for a model consisting of hard spheres colliding elastically against a rigid surface with prescribed microgeometry. Our refinement of the MS theory is based on the observation that the classical surface scattering operator associated to the microgeometry has a canonical velocity space diffusion approximation by a generalized Legendre differential operator whose spectral theory is known explicitly. More specifically, starting from an explicit description of the effective channel surface microgeometry -- a concept which incorporates both the actual surface microgeometry and the molecular radius -- and using this operator approximation, we show that $\vartheta$ can be resolved into easily obtained geometric parameters.Comment: 19 pages, 5 figure

Genome-wide profiling of uncapped mRNA

Gene transcripts are under extensive posttranscriptional regulation, including the regulation of their stability. A major route for mRNA degradation produces uncapped mRNAs, which can be generated by decapping enzymes, endonucleases, and small RNAs. Profiling uncapped mRNA molecules is important for the understanding of the transcriptome, whose composition is determined by a balance between mRNA synthesis and degradation. In this chapter, we describe a method to profile these uncapped mRNAs at the genome scale

Mississippi Canyon 252 Incident NRDA Tier 1 for Deepwater Communities

The northern Gulf of Mexico (GOM) is geologically diverse basin, described as the most complex continental slope region in the world. Regional topography of the slope consists of basins, knolls, ridges, and mounds derived from the dynamic adjustments of salt and the introduction of large volumes of sediment over long time scales. More than 99% of the sea floor in the GOM consists of soft sediment made up of various mixtures of primarily silt and clay. These wide-spread soft bottom communities are described in reports from major MMS studies by Gallaway et al. (1998) and Rowe and Kennicutt (2009). Relative to soft bottoms, hard bottoms and their associated communities are relatively uncommon by are notable for their high biodiversity and complexity

A Whole-Genome RNA Interference Screen Reveals a Role for Spry2 in Insulin Transcription and the Unfolded Protein Response.

Insulin production by the pancreatic β-cell is required for normal glucose homeostasis. While key transcription factors that bind to the insulin promoter are known, relatively little is known about the upstream regulators of insulin transcription. Using a whole-genome RNA interference screen, we uncovered 26 novel regulators of insulin transcription that regulate diverse processes including oxidative phosphorylation, vesicle traffic, and the unfolded protein response (UPR). We focused on Spry2-a gene implicated in human type 2 diabetes by genome-wide association studies but without a clear connection to glucose homeostasis. We showed that Spry2 is a novel UPR target and its upregulation is dependent on PERK. Knockdown of Spry2 resulted in reduced expression of Serca2, reduced endoplasmic reticulum calcium levels, and induction of the UPR. Spry2 deletion in the adult mouse β-cell caused hyperglycemia and hypoinsulinemia. Our study greatly expands the compendium of insulin promoter regulators and demonstrates a novel β-cell link between Spry2 and human diabetes

A multi-modal approach to measuring particulate iron speciation in buoyant hydrothermal plumes

Processes active within buoyant hydrothermal plumes are expected to modulate the flux of elements, such as Fe, to the deep ocean; however, they are yet to be described in a comprehensive manner through observations or models. In this study, we compare observed particulate Fe (pFe) speciation with thermodynamic (equilibrium) reaction path modeling for three vent fields in the Eastern Lau Spreading Center (ELSC). At each site, particles were collected from the buoyant rising portion of hydrothermal plumes using in situ filtration with a Remotely Operated Vehicle. Filter bound particles were analyzed by synchrotron micro-probe X-ray fluorescence mapping (XRF), X-ray diffraction (XRD), XRF spectroscopy, and X-ray absorption near edge structure (XANES) spectroscopy at the Fe 1 s edge, as well as XRF-based chemical speciation mapping for Fe. For buoyant plumes of the ELSC, diversity in solid-state chemistry was high, and poorly crystalline, meta-stable phases were common. We demonstrate that to fully describe the crystalline-to-noncrystalline character of plume pFe, a multi-modal XRD-XANES analytical approach is needed. We found that an equilibrium modeling approach worked well for pyrite but performed poorly for important families of meta-stable pFe, namely Fe (oxyhydr)oxides and monosulfides. Based on our findings, we recommend future field expeditions strategically explore sites representing a diversity of site-specific conditions to better capture the full range of processes active in plumes. We also recommend development of kinetic models, as well as expansion of thermodynamic databases to better reflect the solid-state composition of plumes. These steps should allow oceanographers to understand the processes controlling Fe speciation in plumes well enough to create realistic models of hydrothermal fluxes to the ocean

Estimation of Demand Systems Based on Elasticities of Substitution

This paper develops a model for demand-system estimations, whose coefficients are own-price Marshallian elasticities and elasticities of substitution between goods. The model satisfies the homogeneity, symmetry and, eventually, adding-up restrictions implied by consumer theory, and is primarily useful for the estimation of the demands of several goods of the same industry or group of products. The characteristics of the model are compared to other existing alternatives (logarithmic, translog, AIDS and QUAIDS demand systems). The model is finally applied to estimate the demands for several carbonated soft drinks in Argentina, and its results are presented, together with the ones obtained with the other estimation methods

Quark mass correction to the string potential

A consistent method for calculating the interquark potential generated by the relativistic string with massive ends is proposed. In this approach the interquark potential in the model of the Nambu--Goto string with point--like masses at its ends is calculated. At first the calculation is done in the one--loop approximation and then the variational estimation is performed. The quark mass correction results in decreasing the critical distance (deconfinement radius). When quark mass decreases the critical distance also decreases. For obtaining a finite result under summation over eigenfrequencies of the Nambu--Goto string with massive ends a suitable mode--by--mode subtraction is proposed. This renormalization procedure proves to be completely unique. In the framework of the developed approach the one--loop interquark potential in the model of the relativistic string with rigidity is also calculated.Comment: 34 pages, LATE