Note on consistency between Kalogerakis–Sharma Mechanism (KSM) and two-step mechanism of atmospheric band emission (762 nm)

For more than 30 years, a two-step mechanism was used to explain observed Atmospheric band emission (762 nm) in mesopause region. A new mechanism, which leads to the formation of electronically excited molecular oxygen that gives this emission, was proposed recently. We show, based on an analytical solution, that the fit-functions for Atmospheric band volume emission in the case of the two-step mechanism and the new Kalogerakis–Sharma Mechanism (KSM) have analogous expression. This derivation solves the problem of consistency between the well-known two-step mechanism and the newly proposed KSM

Combating COVID-19: MVA Vector Vaccines Applied to the Respiratory Tract as Promising Approach Toward Protective Immunity in the Lung

The lung is the vital target organ of coronavirus disease 2019 (COVID-19) caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In the majority of patients the most active virus replication seems to be found in the upper respiratory tract, severe cases however suffer from SARS-like disease associated with virus replication in lung tissues. Due to the current lack of suitable anti-viral drugs the induction of protective immunity such as neutralizing antibodies in the lung is the key aim of the only alternative approach—the development and application of SARS-CoV-2 vaccines. However, past experience from experimental animals, livestock, and humans showed that induction of immunity in the lung is limited following application of vaccines at peripheral sides such as skin or muscles. Based on several considerations we therefore propose here to consider the application of a Modified Vaccinia virus Ankara (MVA)-based vaccine to mucosal surfaces of the respiratory tract as a favorable approach to combat COVID-19