Educating students with disabilities who study at the university

In this article the authors aim to analyze the ways of educating students with disabilities. Research activities at the university are the main type of educational and professional activities for students. Students with disabilities have difficulties in organizing research activities. Students have difficulties in self-regulation, their goals in research activities related to internal well-bein

The competency levels of disabled students who study in university

The article is devoted to the problem of inclusive education of students with disabilities at the university. The article analyses the study of the readiness of students with disabilities to research activitie

Hormonal and Barrier Methods of Contraception, Oncogenic Human Papillomaviruses, and Cervical Squamous Intraepithelial Lesion Development

We assessed the influence of hormonal (oral, injectable, or levonorgestrel [Norplant, Wyeth-Ayerst, Philadelphia, PA]) and barrier methods of contraception on the risk of cervical squamous intraepithelial lesions (SIL), while adjusting for high-risk (HR) HPV infection. Subjects were women receiving family planning services through the state health department clinics from 1995 to 1998. We selected 60 cases with high-grade cervical/SIL (HSIL) and 316 with low-grade cervical/SIL (LSIL) and controls (427 women with normal cervical cytology) and analyzed cervical DNA for HR-HPV, using Hybrid Capture I (Digene; Gaithersburg, MD).When assessing ever use, duration, recency, latency, and age at first use, neither oral contraceptives (OC), Norplant, nor injectable use was associated with an increased risk of SIL development after adjusting for age, age at first sexual intercourse, and HR-HPV positivity. Among HR-HPV-positive women, longer duration barrier method use was associated with a reduced risk of SIL. This finding has important clinical implications for SIL prevention among HR-HPV-infected women

Experience of Developing a database of storytellers of the Yakut Epos

The results of the analysis of the basic principles of compiling the database “Olonkhosuts of Yakutia of the 17th—20th centuries” — about the storytellers of the Yakut national epic are presented. The relevance of the research is determined by some difficulties in the systematization and design of the information content of the repository. A brief overview of the history of the study of the personalities of Yakut storytellers is given, the stages of database development are discussed in detail. It is noted that as a result of the generalization of the material a reference book that contains more than 1300 names of storytellers of the 17th-20th centuries was published by the team of the Olonkho Research Institute of M. K. Ammosov North-Eastern Federal University. Problems identified in the process of filling in the cells are described. Particular attention is paid to entering data in the national language, their transliteration and translation into Russian. The definition of the types of the second names of olonkhosuts is given, the expediency of allocating a separate field for nicknames-pseudonyms reflecting the status and popular recognition of the talent of the narrator is substantiated. A sample database table on olonkhosuts is presented. As a result of the study, the parameters for selecting data for inclusion in the repository were compiled, the need for additional research work to identify the facts of the change of residence of olonkhosuts was determined, and recommendations were proposed for improving the principles of information content of the database

Mineral Concentrates As a Factor of the Khibiny Apatite-Nepheline Ores Efficiency Improvement

Apatite-nepheline ores of the Khibiny deposits contain the largest phosphorus-bearing resources in the world, and, at the same time, they contain associated valuable components in the rock-forming minerals — apatite, nepheline, sphene and titanium magnetite. Intensive development of the Khibiny deposits with production of only apatite concentrate and a small part of nepheline concentrate resulted in the accumulation of over 1.0 billion tons of wastes in tailing storage facilities and dumps during 90 years of JSC Apatit operation. The possibility of increasing the efficiency of the use of the main concentrates of apatite-nepheline ores of the Khibiny deposits and wastes for their processing is considered through the use of technological developments of the FRC KSC RAS, JSC RIFI and JSC Apatit to obtain traditional and new target products. A fundamentally new approach to the problem of sustainable use of natural resources is focused on establishment of the whole production chain in the region, from mining and processing operations to manufacturers of final high technology products (rare-earth products, welding and construction materials, coloring agents and other materials). They also determine the level of industrial technical progress. Keywords: Khibiny apatite-nepheline ores, mineral raw materials, extraction and processing, new material

Efficiency of local therapy with the use of a new preparation for oral care at periodontitis in the course of hyperpeptic gastritis after tobacco smoke intoxication

Periodontal diseases, arising against a background of stomach pathology at tobacco addiction remain an acute problem of modern dentistry. The aim of the work is an experimental study of efficiency of application of the new preparation for oral care during treatment of periodontitis simulated against a background of hyperpeptic gastritis under conditions of intoxication by tobacco smoke. At the first stage all experimental animals were divided into 4 groups: І - intact, II - with simulated periodontitis, III - with simulated periodontitis against a background of simulated hyperpeptic gastritis, IV - with simulated periodontitis against a background of hyperpeptic gastritis under conditions of tobacco smoking. Biochemical researches at periodontitis in rats were conducted for determination of influencing stomach pathology and tobacco smoke. On the II stage efficiency of local therapy was studied with the use of the new preparation for oral care and a comparator agent.Results: At experimental periodontitis against a background of hyperpeptic gastritis under conditions of smoking the considerable changes in periodontal tissues typical for the inflammatory process develop. The local therapy at rats with the use of the new preparation resulted in accelerating removing harmful influence of damaging factors and restoring the state of periodontal tissues, than in case of application of the comparator agent. The efficiency of the new preparation consists in normalizing influence on processes of lipid peroxidation, inflammation and activation of the protective systems of oral cavity during periodontitis which arises up against a background of hyperpeptic gastritis

Nanoscale investigation of polymer cement concretes by small angle neutron scattering

An analysis of dense cements, such as polymer cement concrete, is made to produce original innovative components for different types of constructing materials. These materials present good functional properties (ageing resistance, crack formation resistance, hardness, and stability of mechanical modules) and can be used for various applications. In this paper, experimental tests on Portland cement with added γ-Al 2 O 3 and redispersible dry polymer performed using small angle neutron scattering are reported. The objective of the investigation was to assess the key parameters of the material (e.g., porosity, fractal dimensions, and size distribution) at the nanoscale level as well as to obtain useful structural information for expanding the possibility of applications. The results obtained can contribute to the optimisation of the consistency of the material, the design of operating conditions of elements of structures and facilities, and the design of the procedures that support ecological criteria and enhance quality and safety levels. © 2017 Walter de Gruyter GmbH, Berlin/Boston

Biomedical indicators study in terms of the modern type of technogenesis

© 2016, International Journal of Pharmacy and Technology. All rights reserved.Despite the high socio-economic, defense and medical importance, the problem of health development in men of military age and in military servicemen in general has not been sufficiently developed both theoretically and practically [1]. One of the objectives of the current military reform is to ensure medical assistance for military servicemen. The problem of health, the factors affecting the health and quality of life still remain insufficiently studied [2]. The problems of male health and its forming factors are to be developed as a coherent system of social attitudes and traditions of modernity, biomedical, economic, organizational and managerial aspects [3]. This study has applied a set of research methods: biological, chemical, biochemical, clinical, sociological, sociohygienic, immunofluorescent, cytological, statistical, medical and demographic, and clinical methods. Objective of the research is to study the systemically important medicobiological indicators of military technogenesis in order to develop the risk management mechanisms. All subjects were divided into two main groups: control group and experimental group. Control group (C) includes: C1 - civils, and C2 - private soldiers. Experimental group (E) includes: E1 - acting military servicemen, E2 - retired military servicemen. Military servicemen were divided by age, length of service and the type of troops. Age-specific cohort was divided into 6 groups: 18-29, 30-39, 40-49, 50-59, 60-69, and over 70 years old. Gradation according to length of service was as follows: less than 2 years, 3-9 years, 10-19 years, 20-29 years, and 30-39 years. During sociological studies, an attention was given to the production block (occupation, the presence of harmful factors, experience, etc.), medical and biological block (age, presence of chronic diseases, complaints) and social block (presence of harmful habits, diet, lifestyle). Each question and grading of answers had their own diagnostic feature and informational value. The coefficients were evaluated in points. Subject to the score level, four groups of cancer risk were formed: Group 1 (no risk), Group 2 (low risk), Group 3 (medium risk), Group 4 (high risk). The estimation of the immunological status of military servicemen was based on the indicators of humoral and cellular immune system. Analysis of survey and interview results made it possible to determine a significant excess in medium cancer risk in the experimental group as compared with control (42.5% vs. 14.6%). High cancer risk group is characteristic of retired military servicemen (actual retired) - 69.4%. It was determined that the gradation of the immunological states “not changed”, “slightly suppressed immune system”, “sharply suppressed immune system”, “depressed immune system” allowed ranking the immunological status subject to the contingent, the age and length of service. A significantly high immunosuppression value is observed in military servicemen in the age group of 50- 59 years old and with length of service of 15-19 years. According to data analysis of the conducted studies, the significance level of differences in the control and the experimental groups, according to immunologist’s report, is (P≤0.005) P=0.001, x2=0.1662. The comparative analysis also revealed that the group c1kc2e1e2 has statistically significant differences in standard values and values below standard (ρ=0.368). The constructed model of the discriminant function with the resulting index “Immunologist’s report” with the characteristics of P<0.001 and a match of observed and calculated cases of one of the groups - 88.2%, ensures development of management mechanisms for the stabilization and improvement of qualitative and quantitative characteristics of the immune status

dSAP18 and dHDAC1 contribute to the functional regulation of the Drosophila Fab-7 element

It was described earlier that the Drosophila GAGA factor [Trithorax-like (Trl)] interacts with dSAP18, which, in mammals, was reported to be a component of the Sin3–HDAC co-repressor complex. GAGA–dSAP18 interaction was proposed to contribute to the functional regulation of the bithorax complex (BX-C). Here, we show that mutant alleles of Trl, dsap18 and drpd3/hdac1 enhance A6-to-A5 transformation indicating a contribution to the regulation of Abd-B expression at A6. In A6, expression of Abd-B is driven by the iab-6 enhancer, which is insulated from iab-7 by the Fab-7 element. Here, we report that GAGA, dSAP18 and dRPD3/HDAC1 co-localize to ectopic Fab-7 sites in polytene chromosomes and that mutant Trl, dsap18 and drpd3/hdac1 alleles affect Fab-7-dependent silencing. Consistent with these findings, chromatin immunoprecipitation analysis shows that, in Drosophila embryos, the endogenous Fab-7 element is hypoacetylated at histones H3 and H4. These results indicate a contribution of GAGA, dSAP18 and dRPD3/HDAC1 to the regulation of Fab-7 function