Sexual Dysfunctions in Psoriatic Patients

Psoriasis is a chronic, immune-mediated disorder with a worldwide occurrence characterized by well-defined infiltrated erythematous papules and plaques, covered by silvery white or yellowish scales. It is a physically, socially and emotionally invalidating disorder that affects 1-2% of the population. Sexual health is an important part of general health and sexual dysfunctions can negatively affect self-esteem, confidence, interpersonal relationships and the quality of life. Dermatology Life Quality Index (DLQI), Psoriasis Disability Index (PDI) and the Impact of Psoriasis on Quality of Life (IPSO) questionnaire are all questionnaires used to assess the quality of life of patients with psoriasis and each has one question regarding sexual dysfunction. Several scales were also designed to particularly assess sexual satisfaction in men and women. The aim of this paper is to perform an overview of the existing studies on sexual dysfunction in psoriatic patients

Genital Male Piercings

Body piercing has been practiced for thousands of years all over the world for beautification, religion, initiation rites or status reasons. Genital piercings also have a significant background and have been practiced for enhancing sexual pleasure, chastity, shocking or as a protest against a conservative society. As the popularity of genital piercings increased in the last years, the number of complications is also on the rise. It is therefore important for the medical professionals to have at least basic knowledge regarding this practice, as it might be required in the management of unpredictable complications

The impact of microscale street elements on active transport of mobility-restricted individuals: A systematic review

Background Ensuring adequate spatial accessibility to diverse facilities is essential to shaping sustainable, inclusive cities and increasing the well-being of citizens. However, mobility-restricted individuals are found to have lower spatial accessibility in urban areas due to contextual factors, such as physical barriers. Most accessibility assessments focus on the general population and use the road network, due to the lack of data on how contextual factors influence different individuals and lack of geographical data representing pedestrian infrastructure or accessibility features. Methods We searched three databases: Scopus, Web of Science and PubMed. After filtering for eligibility, we examined the remaining 20 studies to understand the perceptions mobility-restricted individuals (i.e., mobility-impaired, visually impaired, or older adults) have of microscale street elements present in urban environments. Data regarding target population groups, data collection methods used and mentioned street elements were extracted. Results The included works tend to focus on a single population group, and disregard within-group differences regarding mobility capacities. Qualitative methods, such as interviews, focus groups and questionnaires, are most frequently used to investigate individual perceptions. To a great extent, individuals perceive microscale street elements differently depending on their mobility capacities. Even if partial overlap exists between population groups, when considering the frequency with which the street elements were mentioned, the impact on their individual accessibility may differ drastically. Certain street elements were highlighted, which can have a twofold effect, acting as barriers for some individuals and facilitators for others. Conclusion The results show that contradicting needs stemming from between- and within-group heterogeneities, together with the highly contextual character of spatial accessibility, pose extensive challenges for designing a barrier-free space for everyone. The results of this review provide a basis for urban planners and policymakers to design the urban infrastructure from a more inclusive perspective, based on comprehensive knowledge

Au-delà des murs : l'intégration du musée de l'Ara Pacis dans le centre historique de Rome

La construction à Rome du musée de l'Ara Pacis, conçu par l'architecte américain Richard Meier, suscite depuis plus de dix ans de vives polémiques. Celles-ci dénotent un malaise évident face à l'intégration d'une architecture contemporaine, qualifiée de « générique » par certains, dans le centre historique de la Ville éternelle. L'argument principal des détracteurs du projet repose sur la thèse selon laquelle la complexité des strates historiques et la diversité étonnante des monuments érigés jadis qui composent cette ville-palimpseste se trouveraient soumises à de trop importants changements nuisant à l'intégrité du patrimoine bâti. En effet, dans le cas étudié ici, ils affirment que le musée de l'Ara Pacis constitue encore un autre cas de structure inapte à rendre justice à l'image historique et patrimoniale de Rome. Il en résulte la question qui est au coeur de la problématique abordée dans ce mémoire: le contact d'une architecture contemporaine, qualifiée de \ud « générique » par ceux qui dénoncent le culte des « archi-stars », avec un monument de la Rome antique, peut-il enrichir l'esprit de ce lieu complexe?\ud Par une analyse du pôle de la réception du monument, ce mémoire vise donc à comprendre les impacts, à différentes échelles, de cette construction par rapport à son contexte urbain. En appliquant une approche inspirée du modèle systémique formulé par l'urbaniste Paolo Colarossi et en recourant notamment au concept de \ud « contemporanéité anachronique » développé par l'historien d'art Daniel Arasse ainsi que celui de monument tel que défini par Jean Davallon, entre autres, nous proposons une piste de résolution de l'opposition entre conservation et innovation. Le discours affectif sera donc dépassé par une analyse plus globale. L'approche systémique utilisée transforme ainsi un cas statique et isolé en événement. Bien encadrées, nous soutenons que les nouvelles architectures peuvent actualiser un bien patrimonial tout en faisant surgir de nouvelles valeurs à transmettre dans le futur. Le débat provoqué par la construction du musée de l'Ara Pacis peut aider à approfondir les réflexions menant à un meilleur encadrement pour des projets futurs. ______________________________________________________________________________ MOTS-CLÉS DE L’AUTEUR : Architecture contemporaine, Paysage urbain historique, Patrimoine, Mise en valeur, Rome, Ara Pacis, Musée de Richard Meier, Approche systémique

Investigating the Dynamics of Nonverbal Communication: Evidence from Neuroimaging in High-Functioning Autism and Typical Development

Being able to accurately decode nonverbal behaviors is essential for human communication. However, meaningful information is not only conveyed by static cues, which have already been extensively investigated in the past, but also by subtle movement dynamics. Investigating such subtle movement dynamics opens up new avenues for the investigation of social cognition in healthy and psychopathological contexts. Thus, this thesis investigated the correlates of perceiving and processing dynamic nonverbal social cues in the human brain using fMRI along with behavioral methods. First, we demonstrate the utility and validity of several digital simulation paradigms for nonverbal behavior research in a neuroimaging context. Further, we show for the first time that the observation of nonverbal communicative interactions is modulated by different spatiotemporal factors of perceived movement and that this is associated with both the AON and the SNN. In addition, we contribute to an ongoing debate by showing that in the context of the observation of complex human interactions, there is no biological bias of the AON. Furthermore, we demonstrate for the first time the domain-specificity of the two neural networks AON and SNN in the context of observing complex human interactions. Finally, we demonstrate that HFA is associated with deficits in social processing more so than social perception, but that social perception may rely on other cognitive strategies compared to typically developing individuals

Les mappings vidéo sur le patrimoine bâti comme forme d’hybridation entre œuvre et dispositif de médiation

Les mappings vidéo, ou projections architecturales 3D, sont une forme de spectacle multimédia qui, lorsque intégré à un édifice patrimonial, convoque un espace de médiations multiples. Les effets visuels et l’iconographie, combinés à la structure et à la charge symbolique de l’édifice, créent un espace physique et virtuel que peut expérimenter le spectateur. Deux exemples de mappings illustrent des stratégies différentes : le Moulin à images pour commémorer les 400 ans de la Ville de Québec sur une structure industrielle et l’Ode à la vie pour célébrer le monument iconique de la Sagrada Familia à Barcelone.Video mappings, or 3D architectural projections, are a form of multimedia spectacle that convenes plural mediation spaces when incorporated to heritage buildings. The meshing of the iconography and the visual effects involved in the projection onto a symbolically charged edifice opens multilayered physical and virtual spaces to be experimented by the viewer. Two types of mappings illustrate different strategies : The Image Mill commemorating Quebec city’s 400th anniversary projected onto an industrial structure, and l’Ode à la vie projected onto an iconic monument, the Sagrada Familia in Barcelona

Why we interact : on the functional role of the striatum in the subjective experience of social interaction

Acknowledgments We thank Neil Macrae and Axel Cleeremans for comments on earlier versions of this manuscript. Furthermore, we are grateful to Dorothé Krug and Barbara Elghahwagi for their assistance in data acquisition. This study was supported by a grant of the Köln Fortune Program of the Medical Faculty at the University of Cologne to L.S. and by a grant “Other Minds” of the German Ministry of Research and Education to K.V.Peer reviewedPreprin

Spatial accessibility assessment of homecare workers to the older population in the city of Zurich

Access to homecare is paramount for the older population wishing not to move to retirement homes. In Zurich, the organization “Spitex Zürich” is the public homecare provider, allowing the older population to experience high-quality life at home through regular visits. A major factor for ensuring self-determined living for the older population consists of a detailed understanding of the spatial accessibility to Spitex locations. Therefore, this paper is concerned with applying four different FCA methods for assessing the spatial accessibility of Spitex homecare workers to people aged 65 + in Zurich through the road and bike networks. The modified-Huff-model-three-step-FCA method is found to be best suited for modeling potential spatial accessibility in Zurich. Spatial accessibility index values show similar geographical distributions regardless of transportation mode. The neighborhoods of Seebach and Hottingen are identified as regions with relatively low spatial accessibility. Our findings contribute to a better understanding of the interpretation and the measurement of spatial accessibility, thereby facilitating autonomous living for the older population residing in Zurich, ultimately increasing the inclusiveness of the city