Flammeum Flaminium. Das ist: HochGräffliches Erbach- und Hohenlohisches Freuden-Gedicht/ und trewhertziger Glückswunsch/ Als ... Herr Georg Albrecht/ Graff zu Erbach ... Mit ... Fräulein Anna Dorothea Christina/ Geborner Gräffin zu Hohenloh Ihr Hochgräfliches Beylager und Hochzeitlichen Ehrentag ... begiengen

FLAMMEUM FLAMINIUM. DAS IST: HOCHGRÄFFLICHES ERBACH- UND HOHENLOHISCHES FREUDEN-GEDICHT/ UND TREWHERTZIGER GLÜCKSWUNSCH/ ALS ... HERR GEORG ALBRECHT/ GRAFF ZU ERBACH ... MIT ... FRÄULEIN ANNA DOROTHEA CHRISTINA/ GEBORNER GRÄFFIN ZU HOHENLOH IHR HOCHGRÄFLICHES BEYLAGER UND HOCHZEITLICHEN EHRENTAG ... BEGIENGEN Flammeum Flaminium. Das ist: HochGräffliches Erbach- und Hohenlohisches Freuden-Gedicht/ und trewhertziger Glückswunsch/ Als ... Herr Georg Albrecht/ Graff zu Erbach ... Mit ... Fräulein Anna Dorothea Christina/ Geborner Gräffin zu Hohenloh Ihr Hochgräfliches Beylager und Hochzeitlichen Ehrentag ... begiengen ([1]r) Einband ( - ) Titelseite ([1]r) Text ([1]v

The Bone Morphogenetic Protein 2 Analogue L51P Enhances Spinal Fusion in Combination with BMP2 in an In Vivo Rat Tail Model.

Bone morphogenic protein 2 (BMP2) is known to induce osteogenesis and is applied clinically to enhance spinal fusion despite adverse effects. BMP2 needs to be used in high doses to be effective due to the presence of BMP2 inhibitors. L51P is a BMP2 analogue that acts by inhibition of BMP2 inhibitors. Here, we hypothesized that mixtures of BMP2 and L51P could achieve better spinal fusion outcomes regarding ossification. To test whether mixtures of both cytokines are sufficient to improve ossification, 45 elderly Wistar rats (of which 21 were males) were assigned to seven experimental groups, all which received spinal fusion surgery, including discectomy at the caudal 4-5 level using an external fixator and a porous β-tricalcium phosphate (βTCP) carrier. These βTCP carriers were coated with varying concentrations of BMP2 and L51P. X-rays were taken immediately after surgery and again six and twelve weeks post-operatively. Histological sections and µCT were analyzed after twelve weeks. Spinal fusion was assessed using X-ray, µCT and histology according to the Bridwell scale by voxel-based quantification and a semi-quantitative histological score, respectively. The results were congruent across modalities and revealed high ossification for high-dose BMP2 (10 µg), while PBS induced no ossification. Low-dose BMP2 (1 µg) or 10 µg L51P alone did not induce relevant bone formation. However, all combinations of low-dose BMP2 with L51P (1 µg + 1/5/10 µg) were able to induce similar ossificationas high-dose BMP2. These results are of high clinical relevance, as they indicate L51P is sufficient to increase the efficacy of BMP2 and thus lower the required dose for spinal fusion. STATEMENT OF SIGNIFICANCE: Spinal fusion surgery is frequently applied to treat spinal pathologies. Bone Morphogenic Protein-2 (BMP2) has been approved by the U .S. Food and Drug Administration (FDA-) and by the "Conformité Européenne" (CE)-label. However, its application is expensive and high concentrations cause side-effects. This research targets the improvement of the efficacy of BMP2 in spinal fusion surgery

Speech and Multimodal Dialogue Systems for

This paper describes work on speech dialogue systems for use via telephone access. One of the activities at FTW is to improve the performance of the automatic speech recognition in such systems by tailoring the speech training data, and thereby the recognition models, to Austrian user groups. Speechdat-AT, a telephone speech database of Austrian German, has been developed which has enabled a reduction of recognition errors by a third compared to a recogniser trained on German data. We also describe the Postal rate Dialogue System developed at FTW, which apart from its realworld usefulness serves as an evaluation platform for our telephony dialogue systems research. Finally we present ongoing research that investigates the integration of speech interfaces with other modalities such as pen input and addresses issues of software architecture

Return to sports/activity level after 360° thoracolumbar fusion after burst fractures in young patients

Introduction: Traumatic thoracolumbar burst fractures are the most common spinal injuries and the proper treatment is controversial. In central Europe in particular, these fractures are often treated with minimally invasive anterior-posterior reduction and fusion, whereas a conservative approach is preferred in the USA. Independent of the treatment strategy, no data exists regarding the outcome related to return to activity level/sport. Research question: The aim of this study was to evaluate the return to sports and activity levels after 360° fusion in patients with thoracolumbar burst fractures without neurological deficits. Methods: Between January 2013 and December 2022, 46 patients aged 18 to 40 years underwent partial or complete vertebral body replacement in the thoracolumbar region due to traumatic burst fractures without neurologic deficit as an isolated injury. Patients were contacted retrospectively by phone calls to assess their activities using a modified version of the Tegner activity scale at different time points: Before trauma, 3, 6, and 12 months post-surgery. Results: After applying exclusion criteria, data collection was complete for 28 patients. The median modified Tegner activity scale was 5.4 before sustaining the fracture, declined to 2.9 at three months post-trauma, improved to 4.2 at six months, and reached 5.0 at 12 months. The majority (83%) of patients achieved their pre-accident activity level within 12 months. No significant differences were observed between patients with partial or complete corpectomy. Conclusion: This is the first study assessing return to sports/physical activity based on the modified Tegner scale in young patients undergoing 360° fusion for spinal burst fractures. The majority of patients (83%) return to the pre-injury activity level within 12 months after surgery

Repairing Annulus Fibrosus Fissures Using Methacrylated Gellan Gum Combined with Novel Silk

Intervertebral disc (IVD) herniation often causes severe pain and is frequently associated with the degeneration of the IVD. As the IVD degenerates, more fissures with increasing size appear within the outer region of the IVD, the annulus fibrosus (AF), favoring the initiation and progression of IVD herniation. For this reason, we propose an AF repair approach based on methacrylated gellan gum (GG-MA) and silk fibroin. Therefore, coccygeal bovine IVDs were injured using a biopsy puncher (⌀ 2 mm) and then repaired with 2% GG-MA as a filler material and sealed with an embroidered silk yarn fabric. Then, the IVDs were cultured for 14 days either without any load, static loading, or complex dynamic loading. After 14 days of culture, no significant differences were found between the damaged and repaired IVDs, except for a significant decrease in the IVDs’ relative height under dynamic loading. Based on our findings combined with the current literature that focuses on ex vivo AF repair approaches, we conclude that it is likely that the repair approach did not fail but rather insufficient harm was done to the IVD

[Stammbuch Andreas Seifart] ; FLORES HESPERIDVM.|| PVLCHERRI=||MAE PLERORVM-||QVE GRAECIAE COMICO-||rum Sententiae, cum duplici earum versione || Latina, tum alijs, tum praecipuè literarum stu-||diosis ... || profuturae.|| Stãm oder Gesellenbuch.|| Mit vil schoenen Spruechen/|| auch allerley offnen vnd Buergerli=||chen Schildten vnd Helmen. Allen Stu=||denten ... || zu dienst || vnd gefallen zusammen || getragen.||

[STAMMBUCH ANDREAS SEIFART] ; FLORES HESPERIDVM.|| PVLCHERRI=||MAE PLERORVM-||QVE GRAECIAE COMICO-||RUM SENTENTIAE, CUM DUPLICI EARUM VERSIONE || LATINA, TUM ALIJS, TUM PRAECIPUÈ LITERARUM STU-||DIOSIS ... || PROFUTURAE.|| STÃM ODER GESELLENBUCH.|| MIT VIL SCHOENEN SPRUECHEN/|| AUCH ALLERLEY OFFNEN VND BUERGERLI=||CHEN SCHILDTEN VND HELMEN. ALLEN STU=||DENTEN ... || ZU DIENST || VND GEFALLEN ZUSAMMEN || GETRAGEN.|| [Stammbuch Andreas Seifart] ; FLORES HESPERIDVM.|| PVLCHERRI=||MAE PLERORVM-||QVE GRAECIAE COMICO-||rum Sententiae, cum duplici earum versione || Latina, tum alijs, tum praecipuè literarum stu-||diosis ... || profuturae.|| Stãm oder Gesellenbuch.|| Mit vil schoenen Spruechen/|| auch allerley offnen vnd Buergerli=||chen Schildten vnd Helmen. Allen Stu=||denten ... || zu dienst || vnd gefallen zusammen || getragen.|| ( - ) Einband ( - ) Titelseite ([2]-[3]) Insignia Domvs Witgensteiniae. / In Insignia Illvstris ... ([4]-[5]) Praefatio. ([6]-[7]) Ad Lectorem ([16]-[17]) Candido Lectori S. (1) Amici. (2) Moritz, Hessen-Kassel, Landgraf; Blatt 10 (10) Johann Ernst, Sachsen-Coburg-Eisenach, Herzog; Blatt 12 (12) Unbekannt, Blatt 18 (18) Thurzó, Imre; Blatt 20 (20) Unbekannt, Blatt 36 (36) Unbekannt, Blatt 38 (38) Wirth, Michael; Blatt 43 (43) Unbekannt, Blatt 67 (67) Unbekannt, Blatt 96 (96) Leyser, Polycarp; Blatt 110 (110) Mylius, Georg; Blatt 111 (111) Neldel, Johann; Blatt 114 (114) Becker, Cornelius; Blatt 124 (124) Schmuck, Vincentius; Blatt 126 (126) Büthner, David; Blatt 127 (127) Schilter, Zacharias; Blatt 142 (142) Johann Kasimir; Blatt 146, 1. Eintrag (146) Ludwig; Blatt 146, 2. Eintrag (146) Helmstatt, Pleickhard von; Blatt 149, 1. Eintrag (149) Heina, Ludwig; Blatt 149, 2. Eintrag (149) Dresser, Matthaeus; Blatt 178 (178) Hirschberger, Erasmus; Blatt 202 (202) Bomsdorff, Hiob von; Blatt 204 (204) Bruno, Christoph; Blatt 208 (208) Seidel, Johann; Blatt 210 (210) Harbart, Burchardus; Blatt 242 (242) Armbruster, Franz; Blatt 259 (259) Zemethey, Paul; Blatt 261 (261) Unbekannt, Blatt 268 (268) Kabe, Daniel; Blatt 273 (273) Cordes, Johann; Blatt 298 (298) Bavarus, Conrad; Blatt 300 (300) Wirth, Michael; Blatt 302 (302) Corvinus, Wolfgang; Blatt 304 (304) Curtius, Johannes; Blatt 306 (306) Spiegel, Jeremias; Blatt 308 (308) Heiligmeyer, Christoph; Blatt 329 (329a) Werner, Peter; Blatt 334 (334) Barth, Johann; Blatt 335 (335) Stuck, Carl; Blatt 336 (336) Eccard, Philipp; Blatt 344 (344) Sartorius, Balthasar; Blatt 346 (346) Einsiedel, Haubold von; Blatt 352 (352) Starzer, Felix; Blatt 358 (358) Barth, Caspar von; Blatt 360 (360) Faber, David; Blatt 360,2 (360a) Hildebrandt, Andreas; Blatt 360,3 (360a) Friesen, Carl von; Blatt 362 (362) Pflug, Bruno; Blatt 364 (364) Bothmer, Wilhelm von; Blatt 368 (368) Bünau, Rudolph von; Blatt 369 (369) Traubot, Friedrich; Blatt 383 (383) Braun, Laurentius; Blatt 387 (387) Aulius, Martin; Blatt 389 (389) Phrysius, Nicolaus; Blatt 390 (390) Rühel, Tiburt; Blatt 421 (390) Hildebrand, Conrad; Blatt 392 (392a) Triller, Michael; Blatt 394 (394) Fritsch, Johann; Blatt 404 (404) Zeis, Leonhard; Blatt 409 (409a) Lederer, Michael; Blatt 424 (424) Schadaeus, Abraham; Blatt 424,2 (424a) Wassaeus, Andreas; Blatt 428 (428) Bornitz, Johannes; Blatt 430 (430) Tilemann, Tobias; Blatt 432 (432) Himmel, Johann; Blatt 432,2 (432a) Cüter, Nicolaus; Blatt 432,3 (432b) Vincentius, Caspar; Blatt 468 (432b) Index. / Register. (433) Insignia Matthaei Harnisch ( - ) Druckvermerk ( - ) Eichhorn, Jeremias; Blatt 469 ( - ) Oertel, Andreas; Blatt 470 (I) Rosenigk, Reinhard Rosa von; Blatt 472 (III) Theodoricus, Petrus; Blatt 473 (IV) Mosbach, Samuel; Blatt 474 (V