Extrapleural harvesting of the internal thoracic artery – impact on early postoperative results and pulmonary function

Introduction: The internal thoracic artery (ITA) has proven to be the best graft for surgical myocardial revascularization, especially in the configuration left ITA (LITA) to the anterior descending branch of left coronary artery (LAD). Its harvesting is usually accompanied by pleurotomy, followed by drainage tube placement into the pleural cavity, using the so called intrapleural method. Extrapleural technique for LITA harvesting is also practiced in many cardiac surgery centers and with this technique the pleura is left intact. Aim: The aim of our study was to investigate the impact of both techniques of LITA harvesting on lung function and incidence of postoperative complications early after operation. Materials and methods: We analyzed retrospectively data of 82 operated patients scheduled for surgical myocardial revascularization and meeting certain inclusion and exclusion criteria. The patients were divided into two groups depending on the way LITA was prepared. Lung parameters and incidence of surgical complications were registered in the early postoperative period until day 30. Results: The patients from both groups had similar preoperative characteristics and risk factors. Those with preserved pleura showed significantly better results of the studied pulmonary parameters and lower complications event rate during early postoperative follow-up. Conclusions: Maintaining the pleura integrity during LITA harvesting is beneficial for lung function and reduces the rate of complications in the early postoperative period

Antithrombotic regimens in patients after coronary artery bypass grafting and coronary endarterectomy

Background: Coronary artery bypass grafting (CABG) remains the gold standard in the treatment of complex chronic forms of coronary heart disease (CHD). Coronary endarterectomy (CEAE) is a useful adjunctive technique to CABG in patients with diffuse coronary artery disease. In order to maintain the patency of the coronary arteries and graft conduits, various antithrombotic protocols have been introduced over the years, combining various antiplatelet and anticoagulant drugs, but still there is no consensus. Aim: The aim of the study is to compare results between two antithrombotic regimens after CEAE. The first one is a combination of acenocoumarol combined with acetylsalicylic acid (ASA), the second regimen is a dual antiplatelet therapy (DAPT) of clopidogrel combined with ASA. Material and methods: We retrospectively reviewed 56 consecutive patients (60 ± 8.2 years) undergoing isolated CABG in association with CEAE between January 2018 and December 2019. In the postoperative period, patients were divided into two groups according to the antithrombotic regimens described above. Twenty-four were in the ASA and acenocoumarol group (AA) and 32 were in the ASA and clopidogrel group (AC). Patients were followed up to 30 days after the operation and we access the mortality rate, new ECG changes, levels of myocardial fraction of creatinine phosphokinase (CPK-MB), left ventricular systolic function, pericardial or pleural effusions requiring drainage or revision for bleeding. Results: Operative mortality was 3,6 %. No differences in the antithrombotic efficacy of the two regimens. A significantly higher level of hemorrhagic complications was observed in the ASA + acenocoumarol treatment group. Conclusion: Dual antiplatelet therapy (DAPT) after CABG and coronary endarterectomy is an effective pharmacological regimen in regard to 30-day postoperative outcomes and is considerably safety in terms of bleeding complications