Vibrational Energy Levels of the Simplest Criegee Intermediate (CH₂OO) from Full-dimensional Lanczos, MCTDH, and MULTIMODE Calculations

Accurate vibrational energy levels of the simplest Criegee intermediate (CH2OO) were determined on a recently developed ab initio based nine-dimensional potential energy surface using three quantum mechanical methods. the first is the iterative Lanczos method using a conventional basis expansion with an exact Hamiltonian. the second and more efficient method is the multi-configurational time-dependent Hartree (MCTDH) method in which the potential energy surface is refit to conform to the sums-of-products requirement of MCTDH. Finally, the energy levels were computed with a vibrational self-consistent field/virtual configuration interaction method in MULTIMODE. the low-lying levels obtained from the three methods are found to be within a few wave numbers of each other, although some larger discrepancies exist at higher levels. the calculated vibrational levels are very well represented by an anharmonic effective Hamiltonian

Some field experience with subsynchronous vibration of centrifugal compressors

A lot of large chemical fertilizer plants producing 1000 ton NH3/day and 1700 ton urea/day were constructed in the 1970's in China. During operation, subsynchronous vibration takes place occasionally in some of the large turbine-compressor sets and has resulted in heavy economic losses. Two cases of subsynchronous vibration are described: Self-excited vibration of the low-pressure (LP) cylinder of one kind of N2-H2 multistage compressor; and Forced subsynchronous vibration of the high-pressure (HP) cylinder of the CO2 compressor

Critical Dimension for Stable Self-gravitating Stars in AdS

We study the self-gravitating stars with a linear equation of state, $P=a \rho$, in AdS space, where $a$ is a constant parameter. There exists a critical dimension, beyond which the stars are always stable with any central energy density; below which there exists a maximal mass configuration for a certain central energy density and when the central energy density continues to increase, the configuration becomes unstable. We find that the critical dimension depends on the parameter $a$, it runs from $d=11.1429$ to 10.1291 as $a$ varies from $a=0$ to 1. The lowest integer dimension for a dynamically stable self-gravitating configuration should be $d=12$ for any $a \in [0,1]$ rather than $d=11$, the latter is the case of self-gravitating radiation configurations in AdS space.Comment: Revtex, 11 pages with 7 eps figure

FSD-C10, a Fasudil derivative, promotes neuroregeneration through indirect and direct mechanisms.

FSD-C10, a Fasudil derivative, was shown to reduce severity of experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS), through the modulation of the immune response and induction of neuroprotective molecules in the central nervous system (CNS). However, whether FSD-C10 can promote neuroregeneration remains unknown. In this study, we further analyzed the effect of FSD-C10 on neuroprotection and remyelination. FSD-C10-treated mice showed a longer, thicker and more intense MAP2 and synaptophysin positive signal in the CNS, with significantly fewer CD4(+) T cells, macrophages and microglia. Importantly, the CNS of FSD-C10-treated mice showed a shift of activated macrophages/microglia from the type 1 to type 2 status, elevated numbers of oligodendrocyte precursor cells (OPCs) and oligodendrocytes, and increased levels of neurotrophic factors NT-3, GDNF and BDNF. FSD-C10-treated microglia significantly inhibited Th1/Th17 cell differentiation and increased the number of IL-10(+) CD4(+) T cells, and the conditioned medium from FSD-C10-treated microglia promoted OPC survival and oligodendrocyte maturation. Addition of FSD-C10 directly promoted remyelination in a chemical-induced demyelination model on organotypic slice culture, in a BDNF-dependent manner. Together, these findings demonstrate that FSD-C10 promotes neural repair through mechanisms that involved both immunomodulation and induction of neurotrophic factors

A Note on Self-gravitating Radiation in AdS Spacetime

In this paper we investigate the equilibrium self-gravitating radiation in higher dimensional, plane symmetric anti-de Sitter space. We find that there exist essential differences from the spherically symmetric case: In each dimension ($d\geq 4$), there are maximal mass (density), maximal entropy (density) and maximal temperature configurations, they do not appear at the same central energy density; the oscillation behavior appearing in the spherically symmetric case, does not happen in this case; and the mass (density), as a function of the central energy density, increases first and reaches its maximum at a certain central energy density and then decreases monotonically in $4\le d \le 7$, while in $d \geq 8$, besides the maximum, the mass (density) of the equilibrium configuration has a minimum: the mass (density) first increases and reaches its maximum, then decreases to its minimum and then increases to its asymptotic value monotonically. The reason causing the difference is discussed.Comment: Revtex, 13 pages with 8 eps figures, to appear in PRD; v2: typos corrected and the version in PR

The divided brain : Functional brain asymmetry underlying self-construal

Acknowledgments This research is partly supported by the National Natural Science Foundation of China (62071049, 61801026) & Capital Medical University Advanced Innovation Center for Big Data-Based Precision Medicine Plan (BHME-201907), and the Leverhulme Trust (RPG-2019-010).Peer reviewedPublisher PD