22 research outputs found
2-Ethoxy-5-methylbis[1,2,4]triazolo[1,5-a:4′,3′-c]quinazoline
The title compound, C13H12N6O, is a functionalized ditriazoloquinazoline with substituted ethoxy and methyl groups attached at the 2-position of each triazole spacer. The fused-ring system is essentially planar [r.m.s. deviation = 0.016 (2) Å]. In the crystal, a weak C—H⋯N hydrogen bond connects the molecules into a chain along [101]
2-Benzyloxy-1,2,4-triazolo[1,5-a]quinazolin-5(4H)-one
The title compound, C16H12N4O2, is a functionalized triazoloquinazoline with a substituted benzyloxy group attached at the 2-position of a triazole spacer. The triazoloquinazoline fused-ring system is approximately planar (r.m.s. deviation = 0.016 Å) while the benzyl substituent is perpendicular to the ring system, making a dihedral angle of 65.29 (6)°. The phenyl ring of the benzyloxy moiety is equally disordered over two sets of sites. A centrosymmetric N—H⋯N hydrogen bond connects molecules into dimers
Ethyl 3-[7-ethoxy-6-(4-methoxybenzenesulfonamido)-2H-indazol-2-yl]propanoate
In the title compound, C21H25N3O6S, the dihedral angle between the methoxybenzene and indazole rings is 74.96 (5)°. The crystal packing is stabilized by an N—H⋯O hydrogen bond into a two-dimensional network. In addition, C—H⋯π interactions and a π–π contact, with a centroid–centroid distance of 3.5333 (6) Å, are observed. The crystal packing is stabilized by N—H⋯O and C—H⋯O hydrogen bonds
Synthese, Reaktivität und fungizide Eigenschaften von 4-Hydroxy(Alkoxy)iminooxazolidin-2-onen
4-Hydroxyimino-oxazolidin-2-ones (3) were prepared by hydroxylaminolysis of 4-alkoxy-3-oxazolin-2-ones (2). Treatment of 3a with ethyl chloroformate in a molar ratio of 1:1 afforded 6, whereas the reaction 3a with two equivalents of ethyl chloroformate produced 4 and 5. By reacting 3a,d with diphosgene or thiophosgene the novel tetrahydro-oxazolo[ 4,3-c]1 ,2,4-oxadiazoles 7 could beobtained in low yields. From the prepared novel compounds only 3a displayed a remarkable fungicidal activity at 2 ppm
Svnthesis of 3-(3.5-Dioxo-[1,2,4]-oxadiazolidin-2-vl)propylphosphonic Acids
Cyclic carbonylation of hydroxyureas 3 with 1,1\u27-carbonyldiimidazole gave 3-(3,5-dioxo-[1,2,4]oxadiazolidin-2yl)propylphosphonic acid diethyl esters 4 which were converted into the corresponding phosphonic acids 5 with bromotrimethylsilane
Al-Salahi, R. Synthesis and Reactivity of [1,2,4]Triazolo-annelated Quinazolines. Molecules 2010, 15, 7016-7034
The authors wish to make the following corrections to the paper published in Molecules [1]: The authorship of the paper is changed to Rashad A. Al-Salahi and Detlef Geffken. [...
Efficient Synthesis of Nα,N-Disubstituted α-Aminocarbohydroxamic Acids
The title compounds 3 can be prepared in good yields by the reaction of N-substituted α-chlorocarbohydroxarnic acids 2 and primary amines in dirnethylacetarnide as solvent