Bewegen in de toekomst: een trend verkenning

Een achtergrondstudie van maatschappelijke, ruimtelijke en technologische trends ten behoeve van de planvorming rond de as Haarlemmermeer-Almer

Prognostic factors for important clinical outcomes in patients with a severe infection

Patients who are admitted with a suspicion of a severe infection usually enter the hospital through the emergency department (ED). The recognition of prognostic factors in an early stage affects further treatment and might improve clinical outcomes. WE EXAMINED POSSIBLE PROGNOSTIC FACTORS FOR FOUR IMPORTANT OUTCOMES: intensive care unit (ICU) admission, positive blood cultures, mortality and re-admission. All adult patients arriving at the ED with a suspected infection for whom admittance and intravenous (iv) antibiotics were indicated were included between March and December 2006. Possible prognostic variables were obtained from medical history, physical examination and laboratory results during the ED presentation. Data were analysed using logistic regression analysis. A total of 295 ED patients were evaluated, of whom 27 were referred to the ICU, 62 had a positive blood culture, 16 died and 48 were re-admitted. In multivariate analysis, patients with a respiration rate of >25/min were at higher risk for ICU admission. Patients with a positive blood culture had a higher heart rate and a higher percentage of segmented neutrophils. Patients who died during admission were more likely to be older, confused and had lower blood pressure. Patients who were re-admitted within 30 days were more likely to be male, younger and less likely to have a positive blood culture. Routine clinical and biochemical information can be used to predict ICU admission, the presence of bacteraemia, mortality and re-admission (within 30 days) and should be taken into consideration for treatment decision

Institutional interventions in complex urban systems: Coping with boundary issues in urban planning projects

__Abstract__ Urban planning projects are planned and organized through arrangements between actors. These arrangements are institutional interventions: they intervene in the institutional landscape as existing organizational boundaries are (temporarily) redrawn. Such boundary decisions are intended to simplify complexity. However, these boundary decisions also produce new complexities as new boundary issu

Afbakeningsperikelen in ruimtelijke projecten

Projectmanagers proberen bewust ruimtelijke projecten af te bakenen om met de complexiteit van de stedelijke omgeving om te kunnen gaan. Daarmee wordt beoogd de externe afhankelijkheden te minimaliseren en zo de complexiteit beheersbaar te maken. Desondanks blijven externe afhankelijkheden bestaan. Voorwaarde om hiermee om te gaan is tijdige reflectie en het toepassen van een coping strategie, in plaats van vasthouden aan achterhaalde grenzen

Asymptotic tunneling conductance in Luttinger liquids

Conductance through weak constrictions in Luttinger liquids is shown to vanish with frequency $\omega$ as $c_1 \omega^2 + c_2 \omega^{2/g - 2}$, where $g$ is a dimensionless parameter characterizing the Luttinger liquid phase, and $c_1$ and $c_2$ are nonuniversal constants. The first term arises from the ^^ Coulomb blockade' effect and dominates for $g < 1/2$, whereas the second results from eliminating high-energy modes and dominates for $g > 1/2$.Comment: Latex file + one appended postcript figur

Analysis of Indoor Rowing Motion using Wearable Inertial Sensors

In this exploratory work the motion of rowers is analyzed while rowing on a rowing machine. This is performed using inertial sensors that measure the orientation at several positions on the body. Using these measurements, this work provides a preliminary analysis of the differences between experienced and novice rowers, or between a good and a bad technique. The analysis shows that the measured postural angles show no clear trend that would set apart experienced and novice rowers or a bad and a good technique. However, there are clear differences in absolute postural angle’s consistency and timing consistency of strokes between novice and experienced rowers. We also applied a machine learning technique to the data to find the similarities between different rowers and an experienced reference rower. The results can be used to compare the quality of the rowing technique with respect to a reference. In this paper, we present our initial results as well as the challenges that need to be further explored

Physical health and the onset and persistence of depression in older adults: an eight-wave prospective community based study.

Background. Poor physical health has long been recognized to be one of the most important risk factors for depression in older adults. Since many aspects of physical health can be targeted for improvement in primary care, it is important to know whether physical health problems predict the onset and/or the persistence of depression. Methods. The study is based on a sample which at the outset consisted of 327 depressed and 325 non-depressed older adults (55-85) drawn from a larger random community-based sample in the Netherlands. Depression was measured using the Center for Epidemiologic Studies Depression scale (CES-D) at eight successive waves. Results. From all incident episodes, the majority (57%) was short-lived. These short episodes could generally not be predicted by physical health problems. The remaining incident episodes (43%) were not short-lived and could be predicted by poor physical health. Chronicity (34%) was also predicted by physical health problems. Conclusions. The study design with its frequent measurements recognized more incident cases than previous studies; these cases however did have a better prognosis than is often assumed. The prognosis of prevalent cases was rather poor. Physical health problems were demonstrated to be a predictor of both the onset and the persistence of depression. This may well have implications for prevention and intervention

Parity Fluctuations Between Coulomb Blockaded Superconducting Islands

We find that if two superconducting islands of different number parity are linked by a tunnel junction the unpaired electron in the odd island has a tendency to tunnel into the even island. This process leads to fluctuations in time of the number parity of each island, giving rise to a random telegraph noise spectrum with a characteristic frequency that has an unusual temperature dependence. This new phenomenon should be observable in a Cooper-pair pump and similar single-electron tunneling devices.Comment: 4 pages, self-unpacking uuencoded gz-compressed postscript file with 3 figures included; also available at http://www.lassp.cornell.edu/janko/publications.htm