Preventive check-up programme for strengthening people-centred primary health care services in Albania: Case study and lessons learnt

Non-communicable Diseases (NCDs) in Albania are increasing, yet the country has a low number of outpatient visits per inhabitant per year. A primary health care (PHC) based programme of medical check-ups, with a focus on prevention, was set up in the country in 2015 aiming to address this issue, among others. This manuscript describes the development and status of the programme at key time points after its implementation, and considers some of its outcomes.The current analysis was based on data gathered from the check-up programme information system and the registry of diseases at PHC centres, and guided by the European Framework for Action on Integrated Health Services Delivery.Based on PHC registered cases, a 13% and 34% increase in the prevalence of elevated blood pres-sure and diabetes were observed in 2015 respectively, following the introduction of the check-up programme compared to the previous year. Three years after implementation, about 60% of the population aged 35–70 years old had used the programme at least once, with 61% of the total 954 667 visits provided to women.Overall, the check-up programme in Albania has identified a substantial number of new cases of NCD as well as their associated risk factors in its population. The early detection of NCDs is expected to contribute to the prevention of complications, premature mortality and their associated costs. Albanian politicians and decision-makers should regularly revise and introduce appropriate changes to the check-up programme in the future. In particular, the issue of sustainability and long-term resource mobilization is of particular concern and warrants careful consideration.   Conflict of interests: None declared

Preventive check-up programme for strengthening people-centred primary health care services in Albania: Case study and lessons learnt

Non-communicable Diseases (NCDs) in Albania are increasing, yet the country has a low number of outpatient visits per inhabitant per year. A primary health care (PHC) based programme of medical check-ups, with a focus on prevention, was set up in the country in 2015 aiming to address this issue, among others. This manuscript describes the development and status of the programme at key time points after its implementation, and considers some of its outcomes.The current analysis was based on data gathered from the check-up programme information system and the registry of diseases at PHC centres, and guided by the European Framework for Action on Integrated Health Services Delivery.Based on PHC registered cases, a 13% and 34% increase in the prevalence of elevated blood pres-sure and diabetes were observed in 2015 respectively, following the introduction of the check-up programme compared to the previous year. Three years after implementation, about 60% of the population aged 35–70 years old had used the programme at least once, with 61% of the total 954 667 visits provided to women.Overall, the check-up programme in Albania has identified a substantial number of new cases of NCD as well as their associated risk factors in its population. The early detection of NCDs is expected to contribute to the prevention of complications, premature mortality and their associated costs. Albanian politicians and decision-makers should regularly revise and introduce appropriate changes to the check-up programme in the future. In particular, the issue of sustainability and long-term resource mobilization is of particular concern and warrants careful consideration.   Conflict of interests: None declared

Hormonal risk factors for ovarian cancer in the Albanian case-control study

The role of reproductive factors in the aetiology of ovarian cancer had been evaluated in hospital-based case-control study conducted in Albania, providing a total dataset of 283 cases and 1019 controls. Logistic regression models were used to obtain relative risk (OR) estimates. The present results showed that parity had protective effects which increased until the forth birth and the trend in risk was significant (p < 0.01). In each stratum and overall, nulliparous women appeared to be at highly increased risk compared to those who had different number of births (OR=12.5, 95%, CI: 2.4-63.8). Evaluation of early age at menarche and late age at menopause, showed statistically significant increased risk. Furthermore, increased risk was observed between pre-menopausal women and never-married nulliparity women, respectively (OR=1.44 95%, CI: 0.88-2.36; OR=8.98, 95%, CI: 1.44 - 56.14), but ovarian cancer risk was reduced for hysterectomized women. These findings suggest that Albanian women have risk factors similar to women in western countries

Primary series COVID-19 vaccine effectiveness among healthcare workers in Albania, February–December 2021

Background: Healthcare workers have experienced high rates of morbidity and mortality from coronavirus disease 2019 (COVID-19). Methods: A prospective cohort study was conducted in three Albanian hospitals between 19 February and 14 December 2021. All participants underwent polymerase chain reaction (PCR) and serological testing at enrolment, regular serology throughout, and PCR testing when symptomatic. Vaccine effectiveness (VE) against COVID-19 and against all severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections (symptomatic or asymptomatic) was estimated. VE was estimated using a Cox regression model, with vaccination status as a time-varying variable. Findings: In total, 1504 HCWs were enrolled in this study; 70% had evidence of prior SARS-CoV-2 infection. VE was 65.1% [95% confidence interval (CI) 37.7–80.5] against COVID-19, 58.2% (95% CI 15.7–79.3) among participants without prior SARS-CoV-2 infection, and 73.6% (95% CI 24.3–90.8) among participants with prior SARS-CoV-2 infection. For BNT162b2 alone, VE was 69.5% (95% CI 44.5–83.2). During the period when the Delta variant was predominant, VE was 67.1% (95% CI 38.3–82.5). VE against SARS-CoV-2 infection for the full study period was 36.9% (95% CI 15.8–52.7). Interpretation: This study found moderate primary series VE against COVID-19 among healthcare workers in Albania. These results support the continued promotion of COVID-19 vaccination in Albania, and highlight the benefits of vaccination in populations with high levels of prior infection

Hormonal risk factors for ovarian cancer in the Albanian case-control study

The role of reproductive factors in the aetiology of ovarian cancer had been evaluated in hospital-based case-control study conducted in Albania, providing a total dataset of 283 cases and 1019 controls. Logistic regression models were used to obtain relative risk (OR) estimates. The present results showed that parity had protective effects which increased until the forth birth and the trend in risk was significant (p < 0.01). In each stratum and overall, nulliparous women appeared to be at highly increased risk compared to those who had different number of births (OR=12.5, 95%, CI: 2.4-63.8). Evaluation of early age at menarche and late age at menopause, showed statistically significant increased risk. Furthermore, increased risk was observed between pre-menopausal women and never-married nulliparity women, respectively (OR=1.44 95%, CI: 0.88-2.36; OR=8.98, 95%, CI: 1.44 - 56.14), but ovarian cancer risk was reduced for hysterectomized women. These findings suggest that Albanian women have risk factors similar to women in western countries

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