Alternative Medicine: A Recent Overview

Alternative medicine has renewed its growing public interest in recent times due to inequality of patients and healthcare professionals’ ratios with increased workload for the latter, various side effects of modern medicine, lack of complete remission from chronic diseases, high cost of new drugs, and emerging new diseases. Hence, people have become more dependent on treatment systems replying on alternative medicine or herbal medicine from traditional medicinal practitioners. Alternative medicine has grown substantially over time and encompasses several millennia of therapeutic systems. The significant areas of alternative medicine include mind–body therapies, body manipulation, and the therapies based on biological systems. Natural products based biological treatment is the most popular of them as nature has endowed us with abundance of effective pharmacologically active phytochemicals. These phytochemicals possess numerous specific clinical health benefits including antioxidant, antidiabetic, anti-inflammatory, anticancer, anti-infectious and analgesic effects. In addition, alternative medicine is easily accessible, affordable, most often noninvasive, and provides favorable benefits during terminal periods of some diseases. However, due to the lack of well-designed clinical trials, the safety and effectiveness of many alternative medicines/therapies remains elusive. This chapter will critically discuss major areas, uses, safety and regulation, current challenges & future perspectives of alternative medicine

Cephalometric Norms of Bangladeshi Young Children Based on McNamara’s Analysis

Objective: To evaluate the cephalometric norms of Bangladeshi young children using McNamara’s analysis. Methods: It was a descriptive cross-sectional study carried out in the Department of Orthodontics, BSMMU among the dental patients visiting Dental OPD of BSMMU. The test sample was 40 Cephalometric radiographs of patients of which 20 were boys (group I) and 20 were girls (group II). The study respondents were of Bangladeshi origin, aged between 11 and 18 years at the time of cephalometric radiograph taken. A randomized sampling technique was followed to collect samples. Results: The mean cephalometric values of McNamara variables were measured and compared with the Caucasian children and Bangladeshi adults. The p values of all variables for Group I (boys) and Group II (girls) were more than 0.05 which was not significant. So it was interpreted that there was no significant difference in the values of McNamara variables between Bangladeshi boys and girls. But in comparison to Caucasian children the p-value of all the variables was significant (<0.05) except Pogonion to Nasion perpendicular. This result suggested that the McNamara variables for Bangladeshi children were significantly different from Caucasian children. Conclusion: The values observed by this study can be used in Bangladeshi children irrespective of gender because there is no statistically significant gender difference. It was also observed that the maxilla of the Bangladeshi children was slightly protrusive but the mandible was retrusive than the Caucasian children and both upper and lower incisors were found proclined

A 14-years old boy having excessive overjet and traumatic bite

This article has no abstract. The first 100 words appear below: A 14-year-old male came to the outpatient Department with the complaints of proclination of the tooth and inability to close his lips. The patient was psychologically depressed for his facial appearance. Extraoral clinical examination showed a mesocephalic symmetrical face with convex facial profile as well as his lower lip was trapped The&nbsp; nasolabial angle was acute. His mandibular movement was normal and there was no temporomandibular joint dysfunction

A 14-years old boy having excessive overjet and traumatic bite

This article has no abstract. The first 100 words appear below: A 14-year-old male came to the outpatient Department with the complaints of proclination of the tooth and inability to close his lips. The patient was psychologically depressed for his facial appearance. Extraoral clinical examination showed a mesocephalic symmetrical face with convex facial profile as well as his lower lip was trapped The&nbsp; nasolabial angle was acute. His mandibular movement was normal and there was no temporomandibular joint dysfunction

Recent Advances in Ovarian Cancer: Therapeutic Strategies, Potential Biomarkers, and Technological Improvements

Aggressive and recurrent gynecological cancers are associated with worse prognosis and a lack of effective therapeutic response. Ovarian cancer (OC) patients are often diagnosed in advanced stages, when drug resistance, angiogenesis, relapse, and metastasis impact survival outcomes. Currently, surgical debulking, radiotherapy, and/or chemotherapy remain the mainstream treatment modalities; however, patients suffer unwanted side effects and drug resistance in the absence of targeted therapies. Hence, it is urgent to decipher the complex disease biology and identify potential biomarkers, which could greatly contribute to making an early diagnosis or predicting the response to specific therapies. This review aims to critically discuss the current therapeutic strategies for OC, novel drug-delivery systems, and potential biomarkers in the context of genetics and molecular research. It emphasizes how the understanding of disease biology is related to the advancement of technology, enabling the exploration of novel biomarkers that may be able to provide more accurate diagnosis and prognosis, which would effectively translate into targeted therapies, ultimately improving patients’ overall survival and quality of life