Resultative Compound Verb in Modern Chinese : A Comment on Imai(1985) and Lu(1986)

<p>A. API and DMO suppresses NF-κB DNA binding ability in HCT116 cells. HCT116 cells were treated with DMO and API at indicated doses, nuclear extracts were prepared, and 20 μg of the nuclear extract protein was used for the ELISA-based DNA-binding assay *p<0.05; **p<0.005). B & C. NF-κB responsive elements linked to a luciferase reporter gene were transfected with wild-type or dominant-negative IκB and transfected cancer cells were treated at indicated doses for 6 h and luciferase activity was measured as described in Materials and Methods section. All luciferase experiments were done in triplicate and repeated twice (*p<0.05; **p<0.005). D. API abrogates constitutive IκBα phosphorylation in dose-dependent manner in HCT116 cells. HCT116 cells were treated with different concentrations of API (0, 5, 10 and 20 μM) for 6 h and cytoplasmic extract was prepared. Lysates were resolved on SDS gel and electrotransferred to a nitrocellulose membrane and probed with anti-phospho-IκBα/IκBα. The blot was washed, exposed to HRP-conjugated secondary antibodies for 1 h, and finally examined by chemiluminescence. GAPDH was used as loading control.</p

Private international law aspects of cross-border wrongs on the internet

<p>Private international law divides the world into territories, each with its own court system and laws. The internet presents challenges to this neat division. It is difficult to identify where an activity takes place on the internet. Wrongs on the internet leave many questions unanswered in transnational litigation. This paper addresses the private international law aspects of cross-border civil wrongs on the internet. Chapter A introduces the internet, and aims to simplify the technical issues. Chapter B asks which court has jurisdiction in a case of wrongs on the internet. The focus is on two sets of rules commonly applied around the globe: the service abroad provisions and the special jurisdiction provisions. The chapter aims to advance general principles applicable in cases of cross-border wrongs committed on the internet, as to the place where a wrong is committed, and the place where damage is suffered. The issue whether a court can grant an injunction against a foreign defendant in respect of foreign conduct is also explored. The exercise of jurisdiction under the service abroad provisions is discretionary. Chapter C examines the <em>forum (non) conveniens</em> discretion in the context of wrongs on the internet. It concludes that, of the US jurisdictional principles developed in internet cases, the sliding scale test should be treated with caution, but the effects test (targeting) should be a factor that is taken into account, in exercising the discretion. Chapter D asks which law applies to a wrong on the internet, concentrating on the divergent choice of law rules in tort in Australia, Canada, the UK and those proposed in the EU. The two chapters that follow consider wrongs to which the internet environment is particularly susceptible, and which deserve separate treatment: intellectual property infringements (Chapter E) and defamation (Chapter F). The final topic, recognition and enforcement of foreign judgments relating to wrongs on the internet, is the subject of Chapter G. The paper rejects the suggestions that new rules should be developed for wrongs on the internet, and concludes that the existing private international law rules are largely workable in the internet context, but require some flexibility in order to be adaptable.</p

Additional file 2: of Chalepin: isolated from Ruta angustifolia L. Pers induces mitochondrial mediated apoptosis in lung carcinoma cells

Manuscript of Del Castillo et al., 1986, i.e. reference [7], entitled "Four aromatic derivatives from Ruta angustifolia." (PDF 131 kb

Effects of DAA-I on expression of IL-6 andTNF-α in plasma of gamma irradiated mice..

<p>Control-1: animals were administered 0.1 ml vehicle (water) and were not irradiated. Control-2: animals were administered vehicle and were irradiated. DAA-I: animals were administered 800 nmole/kg DAA-I and were irradiated. Each value was a mean ± S.E.M. obtained from 3 separate animals. Comparison between groups was analyzed by One-Way ANOVA followed by Tukey’s post-hoc test. * p < 0.05 vs Control-1. ^# p < 0.05 vs Control-2.</p

Kaplan-Meier curve of the effect of DAA-I and DAA-I plus losartan on the survival of mice exposed to 6.4Gy gamma irradiation.

<p>Animals were administered daily vehicle or drug/s on day 1 for a period of 30 days. Control-1: animals were administered 0.1 ml vehicle (water) and were not irradiated. Control-2: animals were administered vehicle and were irradiated. Control-3: animals were administered 800 nmole/kg DAA-I and were not irradiated. DAA-I: animals were administered 800 nmole/kg DAA-I and were irradiated. DAA-I + Los: animals administered 50 nmole/kg losartan and 800 nmole/kg DAA-I and were irradiated.* p< 0.05 vs Control-1. ^# p<0.05 vs Control-2. ^ʌ p<0.05 vs Control-3.</p

Effect of DAA-I and DAA-I plus losartan on the plasma level of PGE₂ in gamma irradiates mice.

<p>Control-1: animals were orally administered 0.1 ml vehicle (water) and were not irradiated. Control-2: animals were orally administered 0.1 ml vehicle and were irradiated. Each value was a mean ± S.E.M. obtained from 3 separate animals. Comparisons between groups was analyzed by One-Way ANOVA followed by Tukey’s post-hoc test. * p< 0.05 vs Control-1; ^# p<0.05 vs Control 2; ^$ p<0.05 vs DAA-I 6.4Gy.</p

Drug administration protocol of non-irradiated and irradiated mice.

<p>Drug administration protocol of non-irradiated and irradiated mice.</p

Temporal profile of circulating PGE₂ in mice treated with 800 nmole/kg DAA-I.

<p>Hollow histograms represent values obtained from mice that were administered vehicle, light solid filled histograms represent values obtained from mice that were administered DAA-I, and the dark solid filled histogram represents value obtained from mice that were administered DAA-I and losartan. Three animals were sacrificed at 1 hour post DAA-I or vehicle administration on the day indicated except on day 15 where the animals were sacrificed without DAA-I or vehicle administration. Each value is a mean ± S.E.M. obtained from 3 animals. Comparisons between groups were analyzed by One-Way ANOVA followed by Tukey’s post-hoc test. * p< 0.05 vs day 0; ^# p<0.05 vs DAA-I day 30.</p