The Relationship Between Education and Police Stress: Bachelor\u27s Degree Versus High School

Sixty law enforcement officers from the largest municipality in the state of West Virginia were evaluated concerning levels of stress or anxiety experienced from organizational issues and interdepartmental rules and regulations. These findings were subsequently compared with the officers level of educational attainment, specifically Bachelor’s degree versus high school education. Specifically, comparisons were made regarding officers with a Bachelor’s degree and those with high school education and scores from the Fear of Negative Evaluation Scale, the Job Satisfaction Index, and the Stress Quiz. Additionally, comparisons of the scores were made between officers with a Bachelor’s degree and officers with a high school education only who had experienced stress from critical incidents. There were no significant findings, however, trends indicated that officers possessing a Bachelor’s degree reported less stress than officers completing only high school

Identification of links between small molecules and miRNAs in human cancers based on transcriptional responses

The use of small molecules to target miRNAs is a new type of therapy for human diseases, particularly cancers. We proposed a novel high-throughput approach to identify the biological links between small molecules and miRNAs in 23 different cancers and constructed the Small Molecule-MiRNA Network (SMirN) for each cancer to systematically analyze the properties of their associations. In each SMirN, we partitioned small molecules (miRNAs) into modules, in which small molecules (miRNAs) were connected with one miRNA (small molecule). Almost all of the miRNA modules comprised miRNAs that had similar target genes and functions or were members of the same miRNA family. Most of the small molecule modules involved compounds with similar chemical structures, modes of action, or drug interactions. These modules can be used to identify drug candidates and new indications for existing drugs. Therefore, our approach is valuable to drug discovery and cancer therapy