Analysis of effectiveness of activities on early detection and treatment of tuberculosis combined with HIV infection at regional level

Presented the results of the analysis of the effectiveness of antituberculous activities and the effectiveness of treatment of patients with tuberculosis, combined with HIV- infection for the period 2010 - 2017 in the Irkutsk region. In order to assess the effectiveness of TB interventions among people with HIV infection in the Irkutsk region, statistical data for 8 years from annual reports and statistical forms were analyzed. During the analyzed period, high effectiveness of antituberculous activities among patients with HIV infection in the Irkutsk region was noted. The key problem is the low adherence of patients with HIV infection to dispensary observation and treatment, and as a consequence, the implementation of preventive measures among them and treatment of tuberculosis. This indicates an unfavorable prognosis of the further spread of tuberculosis among HIV-infected people.Представлены результаты анализа эффективности противотуберкулезных мероприятий и эффективности лечения больных туберкулезом, сочетанным с ВИЧ-инфекцией за период 2010 – 2017гг. в Иркутской области. С целью оценки эффективности мероприятий по туберкулезу среди лиц с ВИЧ-инфекцией в Иркутской области осуществлен анализ статистических данных за 8 лет, полученных из годовых отчетов и статистических форм. За анализируемый период отмечена высокая эффективность противотуберкулезных мероприятий среди больных ВИЧ-инфекцией в Иркутской области. ключевой проблемой является низкая приверженность больных ВИЧ-инфекцией к диспансерному наблюдению и лечению и как следствие, осуществлению среди них профилактических мероприятий и лечения туберкулеза. Это свидетельствует о неблагоприятном прогнозе дальнейшего распространения туберкулеза среди ВИЧ-инфицированных

Энергоэффективное вихревое оборудование

The article presents invention, which allows to create compact and cheap fog-forming devices for industrial hothouses (plants), greenhouses, storehouses, testing polygons and other Objects. Besides, this invention gives the possibilities to modernize the traversers of gas-water fire-fighting type AGVS-100 or AGVS-150, using turbojet engines. Utilization of fog-forming machines among fire-fighting devices will increase the effectiveness in fire-fighting of forest and industrial Objects and oil fields.Представленное в статье изобретение позволит создать компактные и дешевые установки-туманообразователи для промышленных парников, теплиц, складов, испытательных полигонов и других объектов. Кроме того, возможна модернизация передвижных устройств газоводяного пожаротушения типа АГВТ-100 или АГВТ-150, использующих турбореактивные двигатели. Применение установки-туманообразователя в противопожарной технике повысит ее эффективность при тушении лесных пожаров, пожаров на промышленных объектах и нефтепромыслах

Вихревые редукционно-охладительные установки и пароохладители

The authors have developed and tested the entire device class that appeared as a result of fundamental investigations of multiphase flows in centrifugal force fields, understanding of process mechanism occurring in them and their mathematical description for optimization. Method for reduction of pressure and steam temperature in vortex pressure-reducing desuperheating plants and steam coolers has been proposed for the first time in the paper.Авторами разработан и испытан целый класс устройств, которые возникли в результате фундаментальных исследований многофазных течений в центробежных силовых полях, понимания механизмов происходящих в них процессов и их математического описания для оптимизации. Впервые предложен эффективный способ понижения давления и температуры пара в вихревых редукционно-охладительных и пароохладительных устройствах

Возможности повышения эффективности энергетического оборудования при использовании в нем многофазных течений в центробежных силовых полях

A whole class of devices has been developed and tested in the paper. These devices have appeared as a result of fundamental investigations of multi-phase flows in centrifugal power floors, mechanism understanding of processes  which are occurring there and their mathematical description for optimization. It is for the first  time when the paper proposes an efficient method for reduction of steam pressure and temperature in vortex pressure-reducing and desuperheating stations and steam cooling devices. Разработан и испытан целый класс устройств, которые возникли в ре­зультате фундаментальных исследований многофазных течений в центробежных силовых полях, понимания механизмов происходящих в них процессов и их математического описания для оптимизации. Впервые предложен эффективный способ понижения давления и температуры пара в вихревых редукционно-охладительных и пароохладительных устройствах

Energy-Effective Rotation Equipment

The article presents invention, which allows to create compact and cheap fog-forming devices for industrial hothouses (plants), greenhouses, storehouses, testing polygons and other Objects. Besides, this invention gives the possibilities to modernize the traversers of gas-water fire-fighting type AGVS-100 or AGVS-150, using turbojet engines. Utilization of fog-forming machines among fire-fighting devices will increase the effectiveness in fire-fighting of forest and industrial Objects and oil fields

Vortex Pressure-Reducing Desuperheating Plants and Steam Coolers

The authors have developed and tested the entire device class that appeared as a result of fundamental investigations of multiphase flows in centrifugal force fields, understanding of process mechanism occurring in them and their mathematical description for optimization. Method for reduction of pressure and steam temperature in vortex pressure-reducing desuperheating plants and steam coolers has been proposed for the first time in the paper

Evaluation of serum procathepsin B, cystatin B and cystatin C as possible biomarkers of ovarian cancer

Objectives. To evaluate procathepsin B, as well as endogenous inhibitors of cysteine proteases (cystatin B and cystatin C) in biological fluids as possible biomarkers of ovarian cancer. To observe levels of serum procathepsin B in different age groups. Study design. The sample (N=27) of women with gynaecological tumours included 18 patients with ovarian cancer (n=18) and 9 patients with benign ovarian tumours (n=9); 72 healthy women were in the control group. All patients were treated in Novosibirsk Regional Oncological Center, Russia. Serum samples of healthy women (n=40) aged 18–70 years were used as controls for common biomarker of ovarian cancer CA-125. In the Procathepsin B study, serum samples of healthy women (n=32) aged 18–40 years (n=14), 41–55 years (n=10) and 56–80 (n=8) years were used as controls. Methods. Common biomarker of ovarian cancer, CA-125, was assayed by using a commercial kit (Vector, Koltsovo, Novosibirsk Region, Russia). Procathepsin B was measured by means of a commercial kit for human procathepsin B (R&D, USA); cystatin C was measured by commercial ELISA kits for human (BioVendor, Czechia); cystatin B was measured by ELISA kits for human (USCN Life Science Inc., Wuhan, China). Statistical analysis was performed by one-way ANOVA (Statistica 10 Program). Results. In the control group, serum procathepsin B concentration did not reveal age dependency. In the ovarian cancer group, both levels of serum procathepsin B and standard biomarker CA-125 increased significantly (both p<0.001) compared with the control group. In the benign ovarian tumour group, serum procathepsin B (p<0.001) and CA-125 (p=0.004) increased about 2.5- and 8-fold compared to the control group. Serum cystatin B level increased up to 1.7-fold in the ovarian cancer group compared to the control group. The increase of serum CA-125 was about 3.5-fold higher (p=0.017) and procathepsin B was 1.8-fold higher (p<0.05) in the ovarian cancer group compared to the benign tumour group. Cystatin B in ascites fluid increased equally in both ovarian cancer (p<0.001) and benign ovarian tumours group (p<0.05). Cystatin C concentration in ascites fluid increased only in patients with ovarian cancer (p<0.05) and did not change in the benign tumours group. Large increases of procathepsin B level (about 13-fold, p<0.001) and to a lesser degree of cystatin C (1.8-fold, p<0.05) and cystatin B levels (1.4 fold, p<0.001) were revealed in ascites fluids of patients with ovarian cancer compared to the control serum. The significant difference in serum procathepsin B levels was noted between the ovarian cancer and benign tumour groups (p<0.05), which could be used in differential diagnostics between malignant and benign gynaecological tumours. Conclusion. Serum procathepsin B demonstrated significant promise as a new biomarker of ovarian cancer

Possibilities for Higher Efficiency of Power Equipment while Using Multi-Phase Flows in Centrifugal Power Floors

A whole class of devices has been developed and tested in the paper. These devices have appeared as a result of fundamental investigations of multi-phase flows in centrifugal power floors, mechanism understanding of processes  which are occurring there and their mathematical description for optimization. It is for the first  time when the paper proposes an efficient method for reduction of steam pressure and temperature in vortex pressure-reducing and desuperheating stations and steam cooling devices