1 research outputs found
Spiro-indolines for the treatment and prophylaxis of respiratory syncytial virus infection (RSV)
Benzimidazoles of formula (I): wherein: one of X and Y is an N atom or a substituted C atom, and the other is CH; L
o is a single bond, C 1 alkylene, C2 alkenylene or C2 alkynylene; R1 is Ci alkyl, C2 alkenyl, C2 alkynyl, 3- to 10-membered cycloalkyl,
5- to 10-membered heterocyclyl or 5- to 12- membered heteroaryl, each of which is unsubstituted or substituted; Z is halo,
C i haloalkyl, nitro, -CN, -N(R )2, -OR2, -SR2, -S(=0)R 2, or -S(=0) 2R2; each R2 is independently hydrogen, Ci_ alkyl, C2. alkenyl or
o C2-6 alkynyl, wherein said alkyl, alkenyl and alkynyl groups are unsubstituted or substituted; and m is 0 or 1; and the pharmaceutic
ally acceptable salt thereof are inhibitors of RSV and can therefore be used to treat or prevent an RSV infection