286 research outputs found
Books, Theology, and Hens: The Correspondence and Friendship of C. S. Lewis and Dorothy L. Sayers
That Lewis and Sayers had much in common and that their lives intersected in a number of interesting ways throughout their careers is common knowledge for even the casual follower of either author. What does not seem to have been appreciated or explained sufficiently in the scholarship to date is the nature of the friendship between these two influential Christian authors. Therefore, it is this friendship we wish to shed light on, using as our primary source the correspondence between Lewis and Sayers from 1942-1957. In addition, we look at what the biographers of each author have to say about their relationship
Minimum Fee Schedules: Guides or Strait Jackets
Several states have minimum fee schedules that set the least amount of compensation a lawyer should charge for a specific legal service. There has been much confusion in bar associations across the country as to the application of minimum fee schedules and the consequences of non-compliance. The American Bar Association has published both formal and informal opinions in an attempt to clearly define the functions of the schedules. In view of the opinions, interviews and statistical studies on the subject of minimum fee schedules, it is apparent that they are too rigid to cope with the practical needs of the profession but are valuable resources where their function is viewed as a guide. Under the Kansas Relative Value System the lawyer is given a more flexible system that allows him to take into consideration all the necessary factors in arriving at a fair and just fee
Minimum Fee Schedules: Guides or Strait Jackets
Several states have minimum fee schedules that set the least amount of compensation a lawyer should charge for a specific legal service. There has been much confusion in bar associations across the country as to the application of minimum fee schedules and the consequences of non-compliance. The American Bar Association has published both formal and informal opinions in an attempt to clearly define the functions of the schedules. In view of the opinions, interviews and statistical studies on the subject of minimum fee schedules, it is apparent that they are too rigid to cope with the practical needs of the profession but are valuable resources where their function is viewed as a guide. Under the Kansas Relative Value System the lawyer is given a more flexible system that allows him to take into consideration all the necessary factors in arriving at a fair and just fee
Topiramate improves neurovascular function, epidermal nerve fiber morphology, and metabolism in patients with type 2 diabetes mellitus
Amanda L Boyd, Patricia M Barlow, Gary L Pittenger, Kathryn F Simmons, Aaron I VinikDepartment of Internal Medicine, Eastern Virginia Medical School, Norfolk, VA, USAPurpose: To assess the effects of topiramate on C-fiber function, nerve fiber morphology, and metabolism (including insulin sensitivity, obesity, and dyslipidemia) in type 2 diabetes.Patients and methods: We conducted an 18-week, open-label trial treating patients with topiramate. Twenty subjects with type 2 diabetes and neuropathy (61.5 ± 1.29 years; 15 male, 5 female) were enrolled and completed the trial. Neuropathy was evaluated by total neuropathy scores, nerve conduction studies, quantitative sensory tests, laser Doppler skin blood flow, and intraepidermal nerve fibers in skin biopsies.Results: Topiramate treatment improved symptoms compatible with C-fiber dysfunction. Weight, blood pressure, and hemoglobin A1c also improved. Laser Doppler skin blood flow improved significantly after 12 weeks of treatment, but returned to baseline at 18 weeks. After 18 weeks of treatment there was a significant increase in intraepidermal nerve fiber length at the forearm, thigh, and proximal leg. Intraepidermal nerve fiber density was significantly increased by topiramate in the proximal leg.Conclusion: This study is the first to demonstrate that it is possible to induce skin intraepidermal nerve fiber regeneration accompanied by enhancement of neurovascular function, translating into improved symptoms as well as sensory nerve function. The simultaneous improvement of selective metabolic indices may play a role in this effect, but this remains to be determined.Keywords: diabetic neuropathy, skin blood flow, skin biopsy, diabete
Effective Conformal Theory and the Flat-Space Limit of AdS
We develop the idea of an effective conformal theory describing the low-lying
spectrum of the dilatation operator in a CFT. Such an effective theory is
useful when the spectrum contains a hierarchy in the dimension of operators,
and a small parameter whose role is similar to that of 1/N in a large N gauge
theory. These criteria insure that there is a regime where the dilatation
operator is modified perturbatively. Global AdS is the natural framework for
perturbations of the dilatation operator respecting conformal invariance, much
as Minkowski space naturally describes Lorentz invariant perturbations of the
Hamiltonian. Assuming that the lowest-dimension single-trace operator is a
scalar, O, we consider the anomalous dimensions, gamma(n,l), of the
double-trace operators of the form O (del^2)^n (del)^l O. Purely from the CFT
we find that perturbative unitarity places a bound on these dimensions of
|gamma(n,l)|<4. Non-renormalizable AdS interactions lead to violations of the
bound at large values of n. We also consider the case that these interactions
are generated by integrating out a heavy scalar field in AdS. We show that the
presence of the heavy field "unitarizes" the growth in the anomalous
dimensions, and leads to a resonance-like behavior in gamma(n,l) when n is
close to the dimension of the CFT operator dual to the heavy field. Finally, we
demonstrate that bulk flat-space S-matrix elements can be extracted from the
large n behavior of the anomalous dimensions. This leads to a direct connection
between the spectrum of anomalous dimensions in d-dimensional CFTs and
flat-space S-matrix elements in d+1 dimensions. We comment on the emergence of
flat-space locality from the CFT perspective.Comment: 46 pages, 2 figures. v2: JHEP published versio
Decoherence mechanisms of 209Bi donor electron spins in isotopically pure 28Si
Bismuth (209Bi) is the deepest Group V donor in silicon and possesses the
most extreme characteristics such as a 9/2 nuclear spin and a 1.5 GHz hyperfine
coupling. These lead to several potential advantages for a Si:Bi donor electron
spin qubit compared to the more common phosphorus donor. Previous studies on
Si:Bi have been performed using natural silicon where linewidths and electron
spin coherence times are limited by the presence of 29Si impurities. Here we
describe electron spin resonance (ESR) and electron nuclear double resonance
(ENDOR) studies on 209Bi in isotopically pure 28Si. ESR and ENDOR linewidths,
transition probabilities and coherence times are understood in terms of the
spin Hamiltonian parameters showing a dependence on field and mI of the 209Bi
nuclear spin. We explore various decoherence mechanisms applicable to the donor
electron spin, measuring coherence times up to 700 ms at 1.7 K at X-band,
comparable with 28Si:P. The coherence times we measure follow closely the
calculated field-sensitivity of the transition frequency, providing a strong
motivation to explore 'clock' transitions where coherence lifetimes could be
further enhanced.Comment: 5 pages, 4 figure
Very Low-Mass Stellar and Substellar Companions to Solar-Like Stars from MARVELS I: A Low Mass Ratio Stellar Companion to TYC 4110-01037-1 in a 79-day Orbit
TYC 4110-01037-1 has a low-mass stellar companion, whose small mass ratio and
short orbital period are atypical amongst solar-like (Teff ~< 6000 K) binary
systems. Our analysis of TYC 4110-01037-1 reveals it to be a moderately aged
(~<5 Gyr) solar-like star having a mass of 1.07 +/- 0.08 MSun and radius of
0.99 +/- 0.18 RSun. We analyze 32 radial velocity measurements from the
SDSS-III MARVELS survey as well as 6 supporting radial velocity measurements
from the SARG spectrograph on the 3.6m TNG telescope obtained over a period of
~2 years. The best Keplerian orbital fit parameters were found to have a period
of 78.994 +/- 0.012 days, an eccentricity of 0.1095 +/- 0.0023, and a
semi-amplitude of 4199 +/- 11 m/s. We determine the minimum companion mass (if
sin i = 1) to be 97.7 +/- 5.8 MJup. The system's companion to host star mass
ratio, >0.087 +/- 0.003, places it at the lowest end of observed values for
short period stellar companions to solar-like (Teff ~< 6000 K) stars. One
possible way to create such a system would be if a triple-component stellar
multiple broke up into a short period, low q binary during the cluster
dispersal phase of its lifetime. A candidate tertiary body has been identified
in the system via single-epoch, high contrast imagery. If this object is
confirmed to be co-moving, we estimate it would be a dM4 star. We present these
results in the context of our larger-scale effort to constrain the statistics
of low mass stellar and brown dwarf companions to FGK-type stars via the
MARVELS survey.Comment: 22 pages; accepted in A
The Resident Assessment Instrument-Minimum Data Set 2.0 quality indicators: a systematic review
BackgroundThe Resident Assessment Instrument-Minimum Data Set (RAI-MDS) 2.0 is designed to collect the minimum amount of data to guide care planning and monitoring for residents in long-term care settings. These data have been used to compute indicators of care quality. Use of the quality indicators to inform quality improvement initiatives is contingent upon the validity and reliability of the indicators. The purpose of this review was to systematically examine published and grey research reports in order to assess the state of the science regarding the validity and reliability of the RAI-MDS 2.0 Quality Indicators (QIs).MethodsWe systematically reviewed the evidence for the validity and reliability of the RAI-MDS 2.0 QIs. A comprehensive literature search identified relevant original research published, in English, prior to December 2008. Fourteen articles and one report examining the validity and/or reliability of the RAI-MDS 2.0 QIs were included.ResultsThe studies fell into two broad categories, those that examined individual quality indicators and those that examined multiple indicators. All studies were conducted in the United States and included from one to a total of 209 facilities. The number of residents included in the studies ranged from 109 to 5758. One study conducted under research conditions examined 38 chronic care QIs, of which strong evidence for the validity of 12 of the QIs was found. In response to these findings, the 12 QIs were recommended for public reporting purposes. However, a number of observational studies (n=13), conducted in "real world" conditions, have tested the validity and/or reliability of individual QIs, with mixed results. Ten QIs have been studied in this manner, including falls, depression, depression without treatment, urinary incontinence, urinary tract infections, weight loss, bedfast, restraint, pressure ulcer, and pain. These studies have revealed the potential for systematic bias in reporting, with under-reporting of some indicators and over-reporting of others.ConclusionEvidence for the reliability and validity of the RAI-MDS QIs remains inconclusive. The QIs provide a useful tool for quality monitoring and to inform quality improvement programs and initiatives. However, caution should be exercised when interpreting the QI results and other sources of evidence of the quality of care processes should be considered in conjunction with QI results.<br /
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