466 research outputs found

    An Introduction to Volume 8 of \u3ci\u3eThe New Age\u3c/i\u3e

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    Dr. Lee Garver\u27s introduction to The New Age, Volume 8 (November 3, 1910 to April 27, 1911)

    Review of Bernard Shaw and Gabriel Pascal. Edited by Bernard F. Dukore.

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    Dr. Lee Garver\u27s review of Bernard Shaw and Gabriel Pascal. Edited by Bernard F. Dukore. Volume 3 of Selected Correspondence of Bernard Shaw. Toronto: University of Toronto Press, 1996. Pp. 224. $40.00

    An Introduction to Volume 19 of \u3ci\u3eThe New Age\u3c/i\u3e

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    Dr. Lee Garver\u27s introduction to The New Age, Volume 19 (May 4 to October 26, 1916

    Review of Martha Fodeski Black’s Shaw and Joyce: “The Last Word in Stolentelling.”

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    Dr. Lee Garver\u27s review of Shaw and Joyce: The Last Word in Stolentelling. Martha Fodasky Black. Gainesville: University of Florida Press, 1995. Pp. 445. $49.95

    Review of Nagihan Haliloğlu’s Narrating from the Margins: Self-Representation of Female and Colonial Subjectivities in Jean Rhys’s Novels

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    Book review of: Narrating from the Margins: Self-Representation of Female and Colonial Subjectivities in Jean Rhys’s Novels by Nagihan Haliloğlu. 222 pages, 2011, $64.00 USD (hardcover) Amsterdam, Rodop

    Coming in from the Margins: Reappraising and Recentering Katherine Mansfield

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    Review essay of three volumes pertaining to the works of Katherine Mansfield

    Hulme Among the Progressives

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    Dr. Lee Garver\u27s contribution to: Comentale, Edward P., and Andrzej Gąsiorek. T.E. Hulme and the Question of Modernism. Aldershot, England: Ashgate, 2006

    The Political Katherine Mansfield

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    Ideologies that have been superseded by more enduring political discourses and literary figures who have been succeeded by greater authors are frequently relegated to the footnotes of cultural scholarship. But sometimes these lesser-known subjects of literary history, properly attended to, provide unique opportunities for a richer understanding of aesthetic developments. The study of British modernism, in particular, can benefit from a willingness to examine forgotten political-cultural relationships. Indeed, the period\u27s extreme ideological complexity and cross-fertilization has served to mask the important political roles played by less celebrated artists in the formulation of modernist aesthetic doctrine. This is particularly true of Katherine Mansfield

    The Role of RASSF5 on Cell Growth and Hippo Signaling in Rhabdomyosarcoma

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    Introduction: Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma of childhood. Dysregulation of the Hippo pathway, a signaling cascade that regulates many biological processes, is associated with many human cancers. The goal of my project was to delete RASSF5, a regulator of the Hippo pathway, in RMS cells utilizing CRISPR/Cas9 and then to evaluate how the absence of RASSF5 affects RMS cell growth and Hippo signaling, with and without DNMTi Tx. Methods: A lipofectamine transfection was performed in two different RMS cell lines, Rh30 & RD, in which two different CRIPSR/Cas9 vectors with RASSF5 guide RNA were introduced. Then IncuCyte growth assays, western blot and qPCR were performed Results: The IncuCyte growth curve for one of the RASSF5 CRISPR Rh30 cell lines, Sg1, revealed a faster rate of cell growth compared to the control Rh30s. Also, when treated with SGI110 Tx, there is reduction of drug induced growth inhibition of Sg1 Rh30 cells compared to controls. When looking at the protein level, although Cas9 expression was observed, there was no baseline reduction in RASSF5. Discussion: While some of this data suggests that we have less activation of the Hippo pathway, which would result from a reduction in RASSF5, other data implies that RASSF5 was not deleted entirely. Further research is needed to elucidate RASSF5’s role in both RMS and the altered Hippo pathway in RMS

    Dissipation in a superfluid atom circuit

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    Bose-Einstein condensates of weakly interacting dilute atomic gases provide a unique system with which to study phenomena associated with superfluidity. The simplicity of these systems allows us to study the fundamental physics of superfluidity without having to consider the strong interactions present in other superfluid systems such as superconductors and liquid helium. While condensate-based studies have been around for 20 years, our novel approach to confining ultracold atoms has opened a completely new range of parameter space to investigate. Armed with an ability for straightforward creation of arbitrary, time-dependent potential landscapes in which to study superfluid interactions, we were able to take a closer look at predictions of superfluid behavior that are decades old, but until now have never been tested directly. The purpose of this research was to draw direct analogies between superfluid BEC systems, which we term superfluid atom circuits, and existing superconducting circuits, thus allowing us to take advantage of much of the existing knowledge that has come from this well-studied field. Specifically, existing circuits and devices that have been created with superconductors give us insight into what might be possible someday with atom-circuit devices and inspiration to create them. In these experiments, we employed two different atom circuits; one classical (thermal ideal gas) and one quantum (ultracold superfluid). Our results show that each system is equivalent to an electronic circuit consisting of a capacitor being discharged through an inductor in series with some dissipative element. In the thermal system, dissipation can be described in terms of simple resistive flow with the resistance equivalent to ballistic, Sharvin resistance seen in electronic circuits. The superfluid measurements show that the dissipation is best described as a resistance-shunted Josephson junction, which is an analogue to similar devices in superconducting circuits. Additionally, the specific geometry of the atom circuit we used in our superfluid system allowed us to investigate directly a predicted mechanism responsible for the dissipation in superfluids caused by the generation of collective excitations, namely vortices. Direct observation of this mechanism has not previously been possible in superfluid helium and superconducting systems
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