School Administrators’ Perceptions of School Violence

Across America, waves of violence within the school system have shocked and horrified American society. A generation of young people whose main focus should have been on hanging out with friends, getting homework done, not being late to class, going to the mall, or who their date to the prom was to be, instead, are engaged in a sometimes life and death struggle to survive the school day. The tragedy of Columbine High School, where two high school-aged gunmen took the lives of 13 students and teachers and wounded 23 others (Klein and Chancer 2000), while never to be forgotten, should not eclipse the smaller outbreaks of violence that happen in America’s schools on a daily basis

Mapping and assessing variability in the Antarctic marginal ice zone, pack ice and coastal polynyas in two sea ice algorithms with implications on breeding success of snow petrels

© The Author(s), 2016. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in The Cryosphere 10 (2016): 1823-1843, doi:10.5194/tc-10-1823-2016.Sea ice variability within the marginal ice zone (MIZ) and polynyas plays an important role for phytoplankton productivity and krill abundance. Therefore, mapping their spatial extent as well as seasonal and interannual variability is essential for understanding how current and future changes in these biologically active regions may impact the Antarctic marine ecosystem. Knowledge of the distribution of MIZ, consolidated pack ice and coastal polynyas in the total Antarctic sea ice cover may also help to shed light on the factors contributing towards recent expansion of the Antarctic ice cover in some regions and contraction in others. The long-term passive microwave satellite data record provides the longest and most consistent record for assessing the proportion of the sea ice cover that is covered by each of these ice categories. However, estimates of the amount of MIZ, consolidated pack ice and polynyas depend strongly on which sea ice algorithm is used. This study uses two popular passive microwave sea ice algorithms, the NASA Team and Bootstrap, and applies the same thresholds to the sea ice concentrations to evaluate the distribution and variability in the MIZ, the consolidated pack ice and coastal polynyas. Results reveal that the seasonal cycle in the MIZ and pack ice is generally similar between both algorithms, yet the NASA Team algorithm has on average twice the MIZ and half the consolidated pack ice area as the Bootstrap algorithm. Trends also differ, with the Bootstrap algorithm suggesting statistically significant trends towards increased pack ice area and no statistically significant trends in the MIZ. The NASA Team algorithm on the other hand indicates statistically significant positive trends in the MIZ during spring. Potential coastal polynya area and amount of broken ice within the consolidated ice pack are also larger in the NASA Team algorithm. The timing of maximum polynya area may differ by as much as 5 months between algorithms. These differences lead to different relationships between sea ice characteristics and biological processes, as illustrated here with the breeding success of an Antarctic seabird.This work is funded under NASA grant NNX14AH74G and NSF grant PLR 1341548

A Glimpse into NASA Planetary Protection: Bacterial Communities Residing on Mars-Bound Spacecraft

Space agencies, such as NASA, abide by Planetary Protection policies dedicated to preserving the scientific integrity of missions, as well as avoiding contamination of foreign bodies and adverse changes to Earth. Thus, the NASA Standard Assay quantifies heat-tolerant microbes to meet bioburden requirements. Microorganisms collected by the Assay are cultivated to purity and stored in frozen stocks. Bacteria collected from the Mars Exploration Rover and Phoenix missions were revived, then their genomic DNA extracted, 16S rRNA gene amplified and sequenced. Based on the sequences, 101 isolates from the MER craft and 52 isolates from the Phoenix Fairing were identified. Bacillus and Bacillus-like genera comprise over 50% (77 isolates), and Staphylococcus comprise 23% (35 isolates) of the studied isolates. Additionally, low sequence identity (\u3c97%) suggests 4 putative novel species in the Bacillus, Paenibacillus, and Virgibacillus genera. Further biochemical tests will be performed to understand their metabolism and characterize novel species. Novel Paenibacillus species have an uncommon ridge cellular morphology, are able to grow at temperatures ranging from 25°C to over 50°C, and demonstrate unique carbon utilization. The elucidated diversity and physiology enhance microbial reduction techniques and build a bank of false-positives for future missions. Contributors: Garrett Smith, Wayne Schubert, Stephanie Smith, Andrzej Paszczynski, James N. Benardini Affiliation: Jet Propulsion Laboratory, California Institute of Technolog

Food Inflation in Pope County

Although inflation is cooling off in many sectors of the US economy, food inflation continues to surge, indicating the volatility of the agri-food system. The higher food prices make it difficult for US consumers to afford everyday essential food products. The main objective of this research is to calculate food inflation in the pope county area. We utilized the consumer price index (CPI) to measure the change in prices paid by pope county consumers for food. Our preliminary analyses show that food prices in pope county are easing. Specifically, the food inflation rate in pope county declined in March 2023 compared to January 2023

“Growing Together”: Addressing the Support Needs of Caregivers Postpartum Through Occupational Therapy Intervention

Through a collaboration with a practicing occupational therapist in Tacoma, Washington who is currently interested in opening a private practice focused on providing care to caregivers in the postpartum period, the researchers posed the question, “When treating caregivers with children under one year of age, what is the effectiveness of existing interventions within the scope of occupational therapy in improving occupational performance?” Through a critical appraisal of topic project, it was found that the existing evidence supports occupational therapy interventions in the form of brief motivational interviewing, behavioral treatments, self-regulation education, wrist stabilization techniques, and group treatments aimed at decreasing depressive and anxious symptoms. After the critical appraisal of topic project was finalized, researchers completed a needs assessment for the potential future business in the form of a SWOT (strengths, weaknesses, opportunities, threats) analysis. This analysis was informed by a survey dispersed to healthcare professionals treating caregivers in the postpartum period and an interview with a certified nurse midwife in the Tacoma area. Information from the survey and interview indicated that healthcare professionals are unaware of occupational therapy’s role in serving caregivers postpartum but are interested in learning more. Future recommendations include further research on the lived experience of caregivers and how depressive symptoms and role change difficulties affect occupational performance

Activation of p53-regulated pro-apoptotic signaling pathways in PrP-mediated myopathy

<p>Abstract</p> <p>Background</p> <p>We have reported that doxycycline-induced over-expression of wild type prion protein (PrP) in skeletal muscles of Tg(HQK) mice is sufficient to cause a primary myopathy with no signs of peripheral neuropathy. The preferential accumulation of the truncated PrP C1 fragment was closely correlated with these myopathic changes. In this study we use gene expression profiling to explore the temporal program of molecular changes underlying the PrP-mediated myopathy.</p> <p>Results</p> <p>We used DNA microarrays, and confirmatory real-time PCR and Western blot analysis to demonstrate deregulation of a large number of genes in the course of the progressive myopathy in the skeletal muscles of doxycycline-treated Tg(HQK) mice. These include the down-regulation of genes coding for the myofibrillar proteins and transcription factor MEF2c, and up-regulation of genes for lysosomal proteins that is concomitant with increased lysosomal activity in the skeletal muscles. Significantly, there was prominent up-regulation of p53 and p53-regulated genes involved in cell cycle arrest and promotion of apoptosis that paralleled the initiation and progression of the muscle pathology.</p> <p>Conclusion</p> <p>The data provides the first <it>in vivo </it>evidence that directly links p53 to a wild type PrP-mediated disease. It is evident that several mechanistic features contribute to the myopathy observed in PrP over-expressing mice and that p53-related apoptotic pathways appear to play a major role.</p

Environment and Co-occurring Native Mussel Species, but Not Host Genetics, Impact the Microbiome of a Freshwater Invasive Species (Corbicula fluminea)

The Asian clam Corbicula fluminea (Family: Cyneridae) has aggressively invaded freshwater habitats worldwide, resulting in dramatic ecological changes and declines of native bivalves such as freshwater mussels (Family: Unionidae), one of the most imperiled faunal groups. Despite increases in our knowledge of invasive C. fluminea biology, little is known of how intrinsic and extrinsic factors, including co-occurring native species, influence its microbiome. We investigated the gut bacterial microbiome across genetically differentiated populations of C. fluminea in the Tennessee and Mobile River Basins in the Southeastern United States and compared them to those of six co-occurring species of native freshwater mussels. The gut microbiome of C. fluminea was diverse, differed with environmental conditions and varied spatially among rivers, but was unrelated to host genetic variation. Microbial source tracking suggested that the gut microbiome of C. fluminea may be influenced by the presence of co-occurring native mussels. Inferred functions from 16S rRNA gene data using PICRUST2 predicted a high prevalence and diversity of degradation functions in the C. fluminea microbiome, especially the degradation of carbohydrates and aromatic compounds. Such modularity and functional diversity of the microbiome of C. fluminea may be an asset, allowing to acclimate to an extensive range of nutritional sources in invaded habitats, which could play a vital role in its invasive success

The Open Cluster Chemical Analysis and Mapping Survey: Local Galactic Metallicity Gradient with APOGEE using SDSS DR10

The Open Cluster Chemical Analysis and Mapping (OCCAM) Survey aims to produce a comprehensive, uniform, infrared-based dataset for hundreds of open clusters, and constrain key Galactic dynamical and chemical parameters from this sample. This first contribution from the OCCAM survey presents analysis of 141 members stars in 28 open clusters with high-resolution metallicities derived from a large uniform sample collected as part of the SDSS-III/Apache Point Observatory Galactic Evolution Experiment (APOGEE). This sample includes the first high-resolution metallicity measurements for 22 open clusters. With this largest ever uniformly observed sample of open cluster stars we investigate the Galactic disk gradients of both [M/H] and [alpha/M]. We find basically no gradient across this range in [alpha/M], but [M/H] does show a gradient for R_{GC} < 10 kpc and a significant flattening beyond R_{GC} = 10 kpc. In particular, whereas fitting a single linear trend yields an [M/H] gradient of -0.09 +/- 0.03$ dex/kpc --- similar to previously measure gradients inside 13 kpc --- by independently fitting inside and outside 10 kpc separately we find a significantly steeper gradient near the Sun (7.9 <= R_{GC} <= 10) than previously found (-0.20 +/- 0.08 dex/kpc) and a nearly flat trend beyond 10 kpc (-0.02 +/- 0.09 dex/kpc).Comment: 6 pages, 4 figures, ApJ letters, in pres

Anterior Cruciate Ligament Return to Sport after Injury Scale (ACL-RSI) Scores over Time After Anterior Cruciate Ligament Reconstruction: A Systematic Review with Meta-analysis

Background: Psychological readiness is an important consideration for athletes and clinicians when making return to sport decisions following anterior cruciate ligament reconstruction (ACLR). To improve our understanding of the extent of deficits in psychological readiness, a systematic review is necessary. Objective: To investigate psychological readiness (measured via the Anterior Cruciate Ligament-Return to Sport after Injury scale (ACL-RSI)) over time after ACL tear and understand if time between injury and surgery, age, and sex are associated with ACL-RSI scores. Methods: Seven databases were searched from the earliest date available to March 22, 2022. Articles reporting ACL-RSI scores after ACL tear were included. Risk of bias was assessed using the ROBINS-I, RoB-2, and RoBANS tools based on the study design. Evidence certainty was assessed for each analysis. Random-effects meta-analyses pooled ACL-RSI scores, stratified by time post-injury and based on treatment approach (i.e., early ACLR, delayed ACLR, and unclear approach). Results: A total of 83 studies were included in this review (78% high risk of bias). Evidence certainty was ‘weak’ or ‘limited’ for all analyses. Overall, ACL-RSI scores were higher at 3 to 6 months post-ACLR (mean = 61.5 [95% confidence interval (CI) 58.6, 64.4], I2 = 94%) compared to pre-ACLR (mean = 44.4 [95% CI 38.2, 50.7], I2 = 98%), remained relatively stable, until they reached the highest point 2 to 5 years after ACLR (mean = 70.7 [95% CI 63.0, 78.5], I2 = 98%). Meta-regression suggests shorter time from injury to surgery, male sex, and older age were associated with higher ACL-RSI scores only 3 to 6 months post-ACLR (heterogeneity explained R2 = 47.6%), and this reduced 1–2 years after ACLR (heterogeneity explained R2 = 27.0%). Conclusion: Psychological readiness to return to sport appears to improve early after ACL injury, with little subsequent improvement until ≥ 2-years after ACLR. Longer time from injury to surgery, female sex and older age might be negatively related to ACL-RSI scores 12–24 months after ACLR. Due to the weak evidence quality rating and the considerable importance of psychological readiness for long-term outcomes after ACL injury, there is an urgent need for well-designed studies that maximize internal validity and identify additional prognostic factors for psychological readiness at times critical for return to sport decisions. Registration: Open Science Framework (OSF), https://osf.io/2tezs/