The transformation of public space : mobile technology practices and urban liminalities

University of Technology Sydney. Faculty of Design, Architecture and Building.Since the mid-twentieth century, various architectural, urban, cultural, and computer science discourses have advanced the rhetoric that contemporary information and communications technologies (ICTs) will fundamentally transform the built and urban environment. More recently, communications and media studies, as well as computer science allied fields such as human computer interaction (HCI) and interaction design have directed significant attention to the urban contexts in which mobile information and communications technologies (mICT) are used, and on the so-called transformative practices of mobile ‘location-awareness’. These diverse fields, that simultaneously attend to the topics of urbanism, space, and technology, bring alternate perspectives, methods, and theories to bear on the notion of urban transformation. Yet equally, they also contribute to a growing body of discourse that situates mobile technology practices as a force of radical and positive urban transformation. This thesis argues that understanding and representing the impacts of mobile technology practices on the aesthetic, symbolic, and lived experience of urban public space is a contestable territory subject to a range of technical, socio-economic, and cultural variables that are difficult to account for from any singular disciplinary perspective. Accordingly, this thesis adopts an interdisciplinary method that examines the selected discourse through the lens of liminal theory initially developed by anthropologist Victor Turner from observations of tribal ritual (1967, 1974a, 1974b, 1977a, 1977b, 1982, 1985)—a theory that has much to say on the concepts and processes of transformation. This constructs a unique critique of claims that mobile technology practices have transformed urban public space by unpacking and examining a number of underlying assumptions and ideals that connect to key conceptual frameworks as well as disciplinary biases. From this perspective, this thesis argues that while mobile technology practices have influenced urban conditions—in both a positive and negative sense—from social practices, and workplace organisation, to ways of moving, they can be alternately conceptualised as liminal triggers that invoke ambivalent representations of urban public space over its radical transformation. The discourse examined in this thesis points to a significant investment in research that attends to the interrelationships between emerging digital technologies and the built environment in the social, cultural, and computer sciences, whereas limited engagement from the architectural discipline. As a contribution to interdisciplinary thinking the value of this thesis to the architectural discipline lies in its presentation and critique of these alternate disciplinary perspectives that have ‘made visible’ the often-abstract impacts of mobile technology practices on and within urban public space. With an eye to the current technourban imaginary and policy vehicle of the smart city, this thesis contends that from this more informed position the architectural discipline can offer much-needed critique on the relationships between emerging technologies and the built environment. The corollary of engaging and adapting a liminal theoretical gaze here is the problematisation of liminal space itself, and a further contribution to its history and methodological range

Enhancing User-Engagement in the Design Process through Augmented Reality Applications

Augmented Reality (AR) technologies are often perceived as the most impactful method to enhance the communication between the designer and the client during the iterative design process. However, the significance of designing the User Interface (UI) and the User Experience (UX) are often underestimated. To intercede, this research aims to employ new and existing techniques to develop UI's, and comparatively assess ``the accuracy and completeness with which specified users can achieve specified goals in particular environments'' (Stone, 2005) - a notion this research delineates as `effectiveness'. Prompted by the work of key scholars, the developed UI's were assessed through the lens of existing UI evaluation techniques, including: Usability Heuristics (Nielsen, 1994) and Visual and Cognitive Heuristics (Zuk and Carpendale, 2006). In partnership with PTW Architects, characteristics such as the rapidity and complexity of interactions, in conjunction with the interface's simplicity and intuitiveness, were extracted from 15 trials underwent by architectural practitioners. The outcomes of this research highlights strategies for the effective development of user interface design for mobile augmented reality applications

Yeast strains and methods of use thereof

The present invention relates to yeast strains and, in particular, to yeast stains for use in fermentation processes. The invention also relates to methods of fermentation using the yeast strains of the invention either alone or in combination with other yeast strains. The invention thither relates to methods for the selection of yeast strains suitable for fermentation cultures by screening for various metabolic products and the use of specific nutrient sources

Dose-Response Effects of Water Supplementation on Cognitive Performance and Mood in Children and Adults

Water supplementation has been found to facilitate visual attention and short-term memory, but the dose required to improve performance is not yet known. We assessed the dose response effect of water on thirst, mood and cognitive performance in both adults and children. Participants were offered either no water, 25 ml or 300 ml water to drink. Study 1 assessed 96 adults and in Study 2, data are presented from 60 children aged 7-9 years. In both studies, performance was assessed at baseline and 20 minutes after drinking (or no drink); on thirst and mood scales, letter cancellation and a digit span test. For both children and adults, a large drink (300 ml) was necessary to reduce thirst, while a small drink (25 ml) was sufficient to improve visual attention (letter cancellation). In adults, a large drink improved digit span, but there was no such effect in children. In children, but not adults, a small drink resulted in increased thirst ratings. Both children and adults show dose-response effects of drinking on visual attention. Visual attention is enhanced by small amounts of fluid and appears not to be contingent on thirst reduction. Memory performance may be related to thirst, but differently for children and adults. These contrasting dose-response characteristics could imply cognitive enhancement by different mechanisms for these two domains

Flibanserin and 8‐OH‐DPAT Implicate Serotonin in Association between Female Marmoset Monkey Sexual Behavior and Changes in Pair‐Bond Quality

Introduction.  Psychopathological origins of personally distressing, hypoactive sexual desire disorder (HSDD) in women are unknown, but are generally attributed to an inhibitory neural regulator, serotonin (5‐HT). Flibanserin, a 5‐HT 1A agonist and 5‐HT 2A antagonist, shows promise as a treatment for HSDD. Aim.  To test the hypothesis that female marmoset sexual behavior is enhanced by flibanserin and diminished by 8‐OH‐DPAT, in order to evaluate the efficacy of serotonergic modulation of female sexual behavior in a pairmate social setting comparable to humans. Methods.  Sexual and social behavior were examined in eight female marmoset monkeys receiving daily flibanserin (15 mg/kg), 8‐OH‐DPAT (0.1 mg/kg), or corresponding vehicle for 15–16 weeks in a counterbalanced, within‐subject design, while housed in long‐term, stable male–female pairs. Main Outcome Measures.  Marmoset pairmate interactions, including sexual and social behavior, were scored during weeks 5–6 of daily flibanserin, 8‐OH‐DPAT or vehicle treatment. 24‐hour pharmacokinetic profiles of the drugs and their metabolites, as well as drug‐induced acute symptoms of the 5‐HT behavioral syndrome were also assessed. Results.  Two‐way analysis of variance reveals that flibanserin‐treated females attract more male sexual interest ( P  = 0.020) and trigger increased grooming ( P  = 0.001) between partners. In contrast, 8‐OH‐DPAT‐treated females show increased rejection of male sexual advances ( P  = 0.024), a tendency for decreased male sexual interest ( P  = 0.080), and increased aggression with their male pairmates ( P  = 0.049). Conclusions.  While 8‐OH‐DPAT‐treated female marmosets display decreased sexual receptivity and increased aggressive interactions with their male pairmates, flibanserin‐treated female marmosets demonstrate increased affiliative behavior with their male pairmates. Such pro‐affiliation attributes may underlie flibanserin's effectiveness in treating HSDD in women. Aubert Y, Gustison ML, Gardner LA, Bohl MA, Lange JR, Allers KA, Sommer B, Datson NA, and Abbott DH. Flibanserin and 8‐OH‐DPAT implicate serotonin in association between female marmoset monkey sexual behavior and changes in pair‐bond quality. J Sex Med 2012;9:694–707.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90344/1/j.1743-6109.2011.02616.x.pd

Effectiveness of a structured, framework-based approach to implementation: the Researching Effective Approaches to Cleaning in Hospitals (REACH) Trial

BACKGROUND: Implementing sustainable practice change in hospital cleaning has proven to be an ongoing challenge in reducing healthcare associated infections. The purpose of this study was to develop a reliable framework-based approach to implement and quantitatively evaluate the implementation of evidence-based practice change in hospital cleaning. DESIGN/METHODS: The Researching Effective Approaches to Cleaning in Hospitals (REACH) trial was a pragmatic, stepped-wedge randomised trial of an environmental cleaning bundle implemented in 11 Australian hospitals from 2016 to 2017. Using a structured multi-step approach, we adapted the integrated Promoting Action on Research Implementation in Health Services (i-PARIHS) framework to support rigorous and tailored implementation of the cleaning bundle intervention in eleven diverse and complex settings. To evaluate the effectiveness of this strategy we examined post-intervention cleaning bundle alignment calculated as a score (an implementation measure) and cleaning performance audit data collected using ultraviolet (UV) gel markers (an outcome measure). RESULTS: We successfully implemented the bundle and observed improvements in cleaning practice and performance, regardless of hospital size, intervention duration and contextual issues such as staff and organisational readiness at baseline. There was a positive association between bundle alignment scores and cleaning performance at baseline. This diminished over the duration of the intervention, as hospitals with lower baseline scores were able to implement practice change successfully. CONCLUSION: Using a structured framework-based approach allows for pragmatic and successful implementation of clinical trials across diverse settings, and assists with quantitative evaluation of practice change. TRIAL REGISTRATION: Australia New Zealand Clinical Trial Registry ACTRN12615000325505, registered on 4 September 2015

Maternal protein restriction affects fetal ovary development in sheep

Maternal malnutrition has important developmental consequences for the foetus. Indeed, adverse fetal ovarian development could have lifelong impact, with potentially reduced ovarian reserve and fertility of the offspring. This study investigated the effect of maternal protein restriction on germ cell and blood vessel development in the fetal sheep ovary. Ewes were fed control (n = 7) or low protein (n = 8) diets (17.0 g vs 8.7 g crude protein/MJ metabolizable energy) from conception to day 65 of gestation (gd65). On gd65, fetal ovaries were subjected to histological and immunohistochemical analysis to quantify germ cells (OCT4, VASA, DAZL), proliferation (Ki67), apoptosis (caspase 3) and vascularisation (CD31). Protein restriction reduced the fetal ovary weight (P 0.05). The density of germ cells was unaffected by maternal diet (P > 0.05). In the ovarian cortex, OCT4+ve cells were more abundant than DAZL+ve (P 0.05). Similarly, maternal protein restriction had no effect on germ cell proliferation or apoptotic indices (P > 0.05) and the number, area and perimeter of medullary blood vessels and degree of microvascularisation in the cortex (P > 0.05). In conclusion, maternal protein restriction decreased ovarian weight despite not affecting germ cell developmental progress, proliferation, apoptosis, or ovarian vascularity. This suggests that reduced maternal protein has the potential to regulate ovarian development in the offspring

Dancing in the Dark - the never-resting ballet of animal life under the Arctic sea ice

While the Arctic Ocean is changing rapidly, we have barely begun to understand the dynamics of animal life under the permanent sea ice, as it exists today. During the MOSAiC expedition, RV Polarstern was moored to an ice floe and drifted more than 3,000 km across the central Arctic Ocean, enabling multidisciplinary observations of the inter-linked processes in atmosphere, sea ice, ocean and ecosystem. We studied year-round changes in diversity, abundance, vertical distribution, physiology, and ontogeny of Arctic ectotherms from the pack ice at the surface into the deep ocean. Imaging profilers show the fine-scale distribution of zooplankton at high resolution, how the vertical distribution and aggregation of different species change with season, and how zooplankton species prepare for reproduction already in the deepest winter. Systematic sampling with nets shows that the pelagic food web was active from the under-ice habitat down to bathypelagic depths throughout the winter, supporting a variety of predators, such as amphipods, polar cod (Boreogadus saida), and the understudied diversity of jellyfish. The first-ever hydroacoustic survey of the Transpolar Drift recorded the change in pelagic biomass in time and space, and highlights brief periods of diel vertical migration in spring and autumn. Video surveys with a Remotely Operated Vehicle (ROV) documented the use of the under-ice habitat by polar cod and various jellyfishes. A new under-ice net mounted on the ROV can provide new insights in the connection of the life cycles of sympagic amphipods with the seasonal change of sea-ice- and water column properties. We collected thousands of samples for the analysis of condition, physiological parameters, food preference, microplastic, and trophic biomarkers, and conducted numerous rate process measurements including respiration, feeding and reproduction, for key species with the goal of unravelling the sources and fate of carbon in the food web. The first results demonstrate how sampling techniques from the days of Nansen in combination with modern technology can unfold a comprehensive picture of the contribution of Arctic fauna to ecosystem functioning and biogeochemical cycles, as well as their resilience and potential changes in a future seasonally ice-covered Arctic Ocean. We will present and discuss first results and conclusions emerging from our data with regard to the scientific objectives of MOSAiC