On the Interpretation of the Atmospheric Neutrino Data in Terms of Flavor Changing Neutrino Interactions

Flavour changing (FC) neutrino-matter interactions have been proposed as a solution to the atmospheric neutrino anomaly. Here we perform the analysis of the full set of the recent 52 kTy Super-Kamiokande atmospheric neutrino data, including the zenith angle distribution of the contained events as well as the higher energy upward-going stopping and through-going muon events. Our results show that the FC mechanism can describe the full data sample with a chi^2_{min}=44/(33 d.o.f) which is acceptable at the 90% confidence level. The combined analysis confines the amount of FC to be either close to maximal or to the level of about (10-50)%.Comment: 15 pages, 4 Postscript figures, uses ReVTeX. Updated analysis to 52 kTy Super-Kamiokande data. A new figure for the up-down asymmetry is included. Some comments and references are adde

Does the Sun Shine by pp or CNO Fusion Reactions?

We show that solar neutrino experiments set an upper limit of 7.8% (7.3% including the recent KamLAND measurements) to the fraction of energy that the Sun produces via the CNO fusion cycle, which is an order of magnitude improvement upon the previous limit. New experiments are required to detect CNO neutrinos corresponding to the 1.5% of the solar luminosity that the standard solar model predicts is generated by the CNO cycle.Comment: Background information at http://www.sns.ias.edu/~jn

Solar Neutrinos Before and After Neutrino 2004

We compare, using a three neutrino analysis, the allowed neutrino oscillation parameters and solar neutrino fluxes determined by the experimental data available Before and After Neutrino 2004. New data available after Neutrino2004 include refined KamLAND and gallium measurements. We use six different approaches to analyzing the KamLAND data. We present detailed results using all the available neutrino and anti-neutrino data for Delta m^2_{12}, tan^2 theta_{12}, sin^2 theta_{13}, and sin^2 eta (sterile fraction). Using the same complete data sets, we also present Before and After determinations of all the solar neutrino fluxes, which are treated as free parameters, an upper limit to the luminosity fraction associated with CNO neutrinos, and the predicted rate for a 7Be solar neutrino experiment. The 1 sigma (3 sigma) allowed range of Delta m^2_{21} = (8.2 +- 0.3) (^+1.0_-0.8)times 10^{-5} eV^2 is decreased by a factor of 1.7 (5), but the allowed ranges of all other neutrino oscillation parameters and neutrino fluxes are not significantly changed. Maximal mixing is disfavored at 5.8 sigma and the bound on the mixing angle theta_{13} is slightly improved to sin^2 theta_{13}<0.048 at 3 sigma. The predicted rate in a 7Be neutrino-electron scattering experiment is (0.665 +-0.015) of the rate implied by the BP04 solar model in the absence of neutrino oscillations. The corresponding predictions for p-p and pep experiments are, respectively, 0.707 {+0.011}{-0.013} and 0.644 {+0.011}{-0.013}. We derive upper limits to CPT violation in the weak sector by comparing reactor anti-neutrino oscillation parameters with neutrino oscillation parameters. We also show that the recent data disfavor at 91 % CL a proposed non-standard interaction description of solar neutrino oscillations.Comment: Added predictions for p-p and pep neutrino-electron scattering rate; publishe

Global Analysis of Solar Neutrino Oscillations Including SNO CC Measurement

For active and sterile neutrinos, we present the globally allowed solutions for two neutrino oscillations. We include the SNO CC measurement and all other relevant solar neutrino and reactor data. Five active neutrino oscillation solutions (LMA, LOW, SMA, VAC, and Just So2) are currently allowed at 3 sigma; three sterile neutrino solutions (Just So2, SMA, and VAC) are allowed at 3 sigma. The goodness of fit is satisfactory for all eight solutions. We also investigate the robustness of the allowed solutions by carrying out global analyses with and without: 1) imposing solar model constraints on the 8B neutrino flux, 2) including the Super-Kamiokande spectral energy distribution and day-night data, 3) including a continuous mixture of active and sterile neutrinos, 4) using an enhanced CC cross section for deuterium (due to radiative corrections), and 5) a optimistic, hypothetical reduction by a factor of three of the error of the SNO CC rate. For every analysis strategy used in this paper, the most favored solutions all involve large mixing angles: LMA, LOW, or VAC. The favored solutions are robust, but the presence at 3 sigma of individual sterile solutions and the active Just So2 solution is sensitive to the analysis assumptions.Comment: 9 figures, higher resolution versions at http://www.sns.ias.edu/~jnb, added references and clarification

Standard and exotic interpretations of the atmospheric neutrino data

The present status of some theoretical interpretations of the atmospheric neutrino deficit is briefly discussed. Specifically, we show the results for the FC mechanism and for the standard oscillation hypothesis, both in the active and in the sterile channels. All these mechanisms are able to fit the present data to a good statistical level. Among them, the nu_mu --> nu_tau oscillation is certainly the best explanation to the atmospheric neutrino deficit, providing a remarkably good agreement with the data.Comment: 3 pages, 2 figures, talk delivered at the 6th International Workshop on Topics in Astroparticle and Underground Physics (TAUP 99), September 1999, Paris, (to appear in the Conference Proceedings, Nucl. Phys. B (Proc. Suppl.), eds. M. Froissart, J. Dumarchez and D. Vignaud

Health-promoting role of Lactiplantibacillus plantarum isolated from fermented foods

Fermentation processes have been used for centuries for food production and preservation. Besides the contribution of fermentation to food quality, recently, scientific interest in the beneficial nature of fermented foods as a reservoir of probiotic candidates is increasing. Fermented food microbes are gaining attention for their health-promoting potential and for being genetically related to human probiotic bacteria. Among them, Lactiplantibacillus (Lpb.) plantarum strains, with a long history in the food industry as starter cultures in the production of a wide variety of fermented foods, are being investigated for their beneficial properties which are similar to those of probiotic strains, and they are also applied in clinical interventions. Food-associated Lpb. plantarum showed a good adaptation and adhesion ability in the gastro-intestinal tract and the potential to affect host health through various beneficial activities, e.g., antimicrobial, antioxidative, antigenotoxic, antiinflammatory and immunomodulatory, in several in vitro and in vivo studies. This review provides an overview of fermented-associated Lpb. plantarum health benefits with evidence from clinical studies. Probiotic criteria that fermented-associated microbes need to fulfil are also reported

Virología, epidemiología y mecanismos de transmisión del VHB

Illness due to the hepatitis B virus is an enormous problem for international public health, affecting over 300 million persons throughout the world, although its prevalence varies considerably between different geographic areas. The universal vaccination of the newly born, promulgated by the World Health Organisation, has made it possible to partially control the spread of the virus in many countries, including Spain. However, the vaccine does not generate protective antibodies in approximately 5% of the population. Besides, infection by the hepatitis B virus can produce few symptoms and the virus is easily transmitted, making its epidemiological control difficult. On the other hand, the growing flow of bi-directional migration of persons between geographical areas with a moderate or high prevalence and Spain also seems to be contributing to the persistence of the disease in our milieu. All of this makes it compulsory to deploy an ensemble of preventive measures based on an increasingly deep understanding of the biological cycle of the virus. In Spain, as in other regions with a low prevalence, the hepatitis B virus infection is considered chiefly to be a disease of sexual transmission, or else contagion takes place between patients who are users of intravenous drugs. On the other hand, blood transmission is of scarce importance in our milieu. Following exposure to the hepatitis B virus, prophylaxis with immunoglobins and also the administration of the vaccine is highly effective, and acquires special interest for all healthcare workers

Food-borne Lactiplantibacillus plantarum protect normal intestinal cells against inflammation by modulating reactive oxygen species and IL-23/IL-17 axis

Food-associated Lactiplantibacillus plantarum (Lpb. plantarum) strains, previously classified as Lactobacillus plantarum, are a promising strategy to face intestinal inflammatory diseases. Our study was aimed at clarifying the protective role of food-borne Lpb. plantarum against inflammatory damage by testing the scavenging microbial ability both in selected strains and in co-incubation with normal mucosa intestinal cells (NCM460). Here, we show that Lpb. plantarum endure high levels of induced oxidative stress through partially neutralizing reactive oxygen species (ROS), whereas they elicit their production when co-cultured with NCM460. Moreover, pre-treatment with food-borne Lpb. plantarum significantly reduce pro-inflammatory cytokines IL-17F and IL-23 levels in inflamed NCM460 cells. Our results suggest that food-vehicled Lpb. plantarum strains might reduce inflammatory response in intestinal cells by directly modulating local ROS production and by triggering the IL-23/IL-17 axis with future perspectives on health benefits in the gut derived by the consumption of functional foods enriched with selected strains