3,549 research outputs found

    Are CDI Systems Multicolored, Facultative, Helping Greenbeards?

    Get PDF
    Competitive and cooperative interactions between organisms, including bacteria, can significantly impact the composition of a community and the fitness of its members, as well as the fitness of their hosts when communities are living on or within other organisms. Understanding the underlying mechanisms is critical to the development of strategies to control microbiological communities that impact animal and plant health and also for understanding the evolution of social behaviors, which has been challenging for evolutionary biologists. Contact-dependent growth inhibition (CDI) is a phenomenon defined by the delivery of a protein toxin to the cytoplasm of neighboring bacteria upon cell–cell contact, resulting in growth inhibition or death unless a specific immunity protein is present. CDI was first described based on observations of interbacterial killing and has been assumed to function primarily as a means of eliminating competitor cells. However, recent molecular evidence indicates that multiple levels of specificity restrict CDI toxin delivery and activity to the same bacterial strain, and that CDI system proteins can mediate cooperative behaviors among ‘self’ cells, a phenomenon called contact-dependent signaling (CDS). Here we review these recent findings and discuss potential biological and evolutionary implications of CDI system-mediated interbacterial competition and cooperation

    A community-based cooking programme "Eat Better Feel Better" can improve child and family eating behaviours in low socioeconomic groups

    Get PDF
    Background: The immediate and sustained impacts of the Eat Better Feel Better cooking programme (EBFBCP) on food choices and eating behaviours in families and children were evaluated. Methods: The EBFBCP (6 weeks, 2 hours/week) was delivered by community-based organisations in Greater Glasgow and Clyde, Scotland. Before, after and at follow-up, parents/caregivers completed short pictorial questionnaires to report family/child eating behaviours and food literacy. Results: In total, 83 EBFBCPs were delivered and 516 participants enrolled, of which 432 were parents and caregivers. Questionnaire completion rates were 57% (n=250) for before and after and 13% (n=58) for follow-up. Most participants (80%) were female, 25–44 years old (51%) and considered socioeconomically deprived (80%). The immediate effects of the EBFBCP on eating behaviours and food literacy were families ate less takeaway/fast foods (10% reduction, p=0.019) and ready meals (15% reduction, p=0.003) and cooked more from scratch (20% increase, p<0.001). Children’s consumption of discretionary food/drinks was significantly reduced after the EBFBCP for sugary drinks (10% reduction, p=0.012), savoury snacks (18%, p=0.012), biscuits (17%, p=0.007), sweets/chocolates (23%, p=0.002), fried/roasted potatoes (17%, p<0.001) and savoury pastries (11%, p<0.001). The number of fruit (15%, p=0.008) and vegetable portions (10%, p<0.001) increased, while the number of biscuit portions decreased (13%, p=0.005). Parental food label reading increased (calories, 22%; fat, 23%; sugar, 22%; ingredients, 19%; and portion size, 19%). Most changes were sustained at a median of 10 months’ follow-up. Conclusion: The EBFBCP improved children’s and families’ food choices and behaviours. The EBFBCP can be recommended to support families to make better food choices

    A Pharmacology-Based Enrichment Program for Undergraduates Promotes Interest in Science

    Get PDF
    There is a strong need to increase the number of undergraduate students who pursue careers in science to provide the “fuel” that will power a science and technology–driven U.S. economy. Prior research suggests that both evidence-based teaching methods and early undergraduate research experiences may help to increase retention rates in the sciences. In this study, we examined the effect of a program that included 1) a Summer enrichment 2-wk minicourse and 2) an authentic Fall research course, both of which were designed specifically to support students\u27 science motivation. Undergraduates who participated in the pharmacology-based enrichment program significantly improved their knowledge of basic biology and chemistry concepts; reported high levels of science motivation; and were likely to major in a biological, chemical, or biomedical field. Additionally, program participants who decided to major in biology or chemistry were significantly more likely to choose a pharmacology concentration than those majoring in biology or chemistry who did not participate in the enrichment program. Thus, by supporting students\u27 science motivation, we can increase the number of students who are interested in science and science careers

    Endemic Angiostrongyliasis, Rio de Janeiro, Brazil

    Get PDF
    Submitted by Sandra Infurna ([email protected]) on 2016-10-06T12:58:28Z No. of bitstreams: 1 fernando_monteiro_etal_IOC_2011.pdf: 214467 bytes, checksum: 7938fea29a355143991cd4f518b2d970 (MD5)Approved for entry into archive by Sandra Infurna ([email protected]) on 2016-10-06T13:12:13Z (GMT) No. of bitstreams: 1 fernando_monteiro_etal_IOC_2011.pdf: 214467 bytes, checksum: 7938fea29a355143991cd4f518b2d970 (MD5)Made available in DSpace on 2016-10-06T13:12:13Z (GMT). No. of bitstreams: 1 fernando_monteiro_etal_IOC_2011.pdf: 214467 bytes, checksum: 7938fea29a355143991cd4f518b2d970 (MD5) Previous issue date: 2011Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil / Universidade Federal Rural do Rio de Janeiro. Seropédica, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Universidade Federal Rural do Rio de Janeiro. Seropédica, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil

    On the weak lensing masses of a new sample of galaxy groups

    Get PDF
    Galaxy group masses are important to relate these systems with the dark matter halo hosts. However, deriving accurate mass estimates is particularly challenging for low-mass galaxy groups. Moreover, calibration of observational mass-proxies using weak-lensing estimates have been mainly focused on massive clusters. We present here a study of halo masses for a sample of galaxy groups identified according to a spectroscopic catalogue, spanning a wide mass range. The main motivation of our analysis is to assess mass estimates provided by the galaxy group catalogue derived through an abundance matching luminosity technique. We derive total halo mass estimates according to a stacking weak-lensing analysis. Our study allows to test the accuracy of mass estimates based on this technique as a proxy for the halo masses of large group samples. Lensing profiles are computed combining the groups in different bins of abundance matching mass, richness, and redshift. Fitted lensing masses correlate with the masses obtained from abundance matching. However, when considering groups in the low-and intermediate-mass ranges, masses computed according to the characteristic group luminosity tend to predict higher values than the determined by the weak-lensing analysis. The agreement improves for the low-mass range if the groups selected have a central early-Type galaxy. Presented results validate the use of mass estimates based on abundance matching techniques, which provide good proxies to the halo host mass in a wide mass range.Fil: Gonzalez, Elizabeth Johana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Astronomía Teórica y Experimental. Universidad Nacional de Córdoba. Observatorio Astronómico de Córdoba. Instituto de Astronomía Teórica y Experimental; Argentina. Centro Brasileiro de Pesquisas Físicas; BrasilFil: Rodriguez, Facundo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Astronomía Teórica y Experimental. Universidad Nacional de Córdoba. Observatorio Astronómico de Córdoba. Instituto de Astronomía Teórica y Experimental; ArgentinaFil: Merchan, Manuel Enrique. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Astronomía Teórica y Experimental. Universidad Nacional de Córdoba. Observatorio Astronómico de Córdoba. Instituto de Astronomía Teórica y Experimental; ArgentinaFil: Garcia Lambas, Diego Rodolfo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Astronomía Teórica y Experimental. Universidad Nacional de Córdoba. Observatorio Astronómico de Córdoba. Instituto de Astronomía Teórica y Experimental; ArgentinaFil: Makler, Martín. Universidad Nacional de San Martín. Escuela de Ciencia y Tecnología. Centro Internacional de Estudios Avanzados; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Ciencias Físicas. - Universidad Nacional de San Martín. Instituto de Ciencias Físicas; Argentina. Centro Brasileiro de Pesquisas Físicas; BrasilFil: Chalela, Martín. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Astronomía Teórica y Experimental. Universidad Nacional de Córdoba. Observatorio Astronómico de Córdoba. Instituto de Astronomía Teórica y Experimental; ArgentinaFil: Pereira, Maria E. S.. University of Michigan. Department of Physics; Estados UnidosFil: Moraes, Bruno. Universidade Federal do Rio de Janeiro; BrasilFil: Shan, HuanYuan. Chinese Academy of Sciences; República de China. Shanghai Astronomical Observatory; Chin
    corecore