Das ELINET-Projekt. Ziele und Ergebnisse eines europäischen Netzwerks zur Lese- und Schreibförderung

Schriftsprachkompetenz („literacy“) ist eine grundlegende Voraussetzung für Bildung und persönliche Entwicklung, da sie es dem Einzelnen ermöglicht, ein erfülltes und sinnstiftendes Leben zu führen und aktiv am gesellschaftlichen Leben teilzunehmen. Vor diesem Hintergrund ist es alarmierend, dass in Europa eine/r von fünf Fünfzehnjährigen und nahezu 55 Millionen Erwachsene nicht über grundlegende Lese- und Schreibkompetenzen verfügen. Die Europäische Kommission hat 2013 auf diese Herausforderung reagiert mit der Ausschreibung eines 3 Millionen Projekts zum Aufbau eines Europäischen Netzwerks von Organisationen, die sich der Förderung von Lesen und Schreiben widmen. Der Antrag der Projektgruppe ELINET, mit 78 Partner-Organisationen aus 28 europäischen Ländern, bekam schließlich den Zuschlag. Der Beitrag informiert über die Ziele, Organisation und Ergebnisse dieses Projekts und seiner Weiterführung durch die ELINET Association. (Autorin

Literacy in Finland. Country Report. Children and adolescents

European Literacy Policy Network (ELINET

Literacy in Denmark. Country Report. Short Version

European Literacy Policy Network (ELINET

Literacy in Scotland. Country Report. Children and adolescents

European Literacy Policy Network (ELINET

Literacy in the Netherlands. Country Report. Children and adolescents

European Literacy Policy Network (ELINET

Literacy in Portugal: country report: children and adolescents

This report on the state of literacy in Portugal is one of a series produced in 2015 and 2016 by ELINET, the European Literacy Policy Network. ELINET was founded in February 2014 and has 78 partner organisations in 28 European countries1. ELINET aims to improve literacy policies in its member countries in order to reduce the number of children, young people and adults with low literacy skills. One major tool to achieve this aim is to produce a set of reliable, up-to-date and comprehensive reports on the state of literacy in each country where ELINET has one or more partners, and to provide guidance towards improving literacy policies in those countries. The reports are based (wherever possible) on available, internationally comparable performance data, as well as reliable national data provided (and translated) by our partners.ELINET - EAC/S05/201

Characterization of JG024, a pseudomonas aeruginosa PB1-like broad host range phage under simulated infection conditions

<p>Abstract</p> <p>Background</p> <p><it>Pseudomonas aeruginosa </it>causes lung infections in patients suffering from the genetic disorder Cystic Fibrosis (CF). Once a chronic lung infection is established, <it>P. aeruginosa </it>cannot be eradicated by antibiotic treatment. Phage therapy is an alternative to treat these chronic <it>P. aeruginosa </it>infections. However, little is known about the factors which influence phage infection of <it>P. aeruginosa </it>under infection conditions and suitable broad host range phages.</p> <p>Results</p> <p>We isolated and characterized a phage, named JG024, which infects a broad range of clinical and environmental <it>P. aeruginosa </it>strains. Sequencing of the phage genome revealed that the phage JG024 is highly related to the ubiquitous and conserved PB1-like phages. The receptor of phage JG024 was determined as lipopolysaccharide. We used an artificial sputum medium to study phage infection under conditions similar to a chronic lung infection. Alginate production was identified as a factor reducing phage infectivity.</p> <p>Conclusions</p> <p>Phage JG024 is a suitable broad host range phage which could be used in phage therapy. Phage infection experiments under simulated chronic lung infection conditions showed that alginate production reduces phage infection efficiency.</p

Study protocol for a prospective, non-controlled, multicentre clinical study to evaluate the diagnostic accuracy of a stepwise two-photon excited melanin fluorescence in pigmented lesions suspicious for melanoma (FLIMMA study)

Introduction: Non-invasive, nanosecond, stepwise two-photon laser excitation of skin tissue was shown to induce melanin fluorescence spectra that allow for the differentiation of melanocytic nevi from cutaneous melanoma. Methods and analysis: This prospective, non-controlled, multicentre clinical study is performed to evaluate the diagnostic performance of the stepwise two-photon excited melanin fluorescence in the detection of cutaneous melanoma. The comparator will be the histopathological diagnosis. A total of 620 pigmented skin lesions suspicious for melanoma and intended for excision will be enrolled. Ethics and dissemination: Ethics approval was provided by the local ethics committees of the medical faculties of the University of Tuebingen, Heidelberg and Berlin. Study registration: The FLIMMA study NCT02425475