The Effect of Explosion-suppression Materials on the Effective Volume and Cook-off Properties of Fuel Tank

In this paper, three kinds of explosion-suppression materials including aluminum alloy, polyurethane foam and spherical polymer are measured to get the data of displacement ratio and retention ratio, which can be used to calculate the reduction ratio of effective volume of the oil tank. The results show that the displacement ratio of the three kinds of materials are respectively 2.0%, 2.5% and 5.2%, the retention ratio are respectively 1.1%, 3.2% and 0.4% and the reduction ratio of effective volume are respectively 3.1%, 5.7% and 5.6%. Meanwhile, the cook-off properties of the oil tank filled with spherical high molecular explosion-suppression materials were tested, the methanol in the tank didn’t explode, and materials in the tank didn’t deform and be destroyed during the experiments. All of the results showed that the spherical high molecular explosion-suppression materials presented a good explosion-suppression performance

The Effect of Explosion-suppression Materials on the Effective Volume and Cook-off Properties of Fuel Tank

In this paper, three kinds of explosion-suppression materials including aluminum alloy, polyurethane foam and spherical polymer are measured to get the data of displacement ratio and retention ratio, which can be used to calculate the reduction ratio of effective volume of the oil tank. The results show that the displacement ratio of the three kinds of materials are respectively 2.0%, 2.5% and 5.2%, the retention ratio are respectively 1.1%, 3.2% and 0.4% and the reduction ratio of effective volume are respectively 3.1%, 5.7% and 5.6%. Meanwhile, the cook-off properties of the oil tank filled with spherical high molecular explosion-suppression materials were tested, the methanol in the tank didn’t explode, and materials in the tank didn’t deform and be destroyed during the experiments. All of the results showed that the spherical high molecular explosion-suppression materials presented a good explosion-suppression performance

Gender-specific associations between atherogenic index of plasma and the presence and severity of acute coronary syndrome in very young adults: a hospital-based observational study

Abstract Objective The value of atherogenic index of plasma (AIP) as a predictive biomarker for coronary artery disease (CAD) remains controversial. In addition, whether AIP is associated with the risk of acute coronary syndrome (ACS) in very young adults has not been well established. Methods We consecutively collected very young adults (≤35 years of age) undergoing coronary angiography (CAG) at Anzhen Hospital, between January 2008 and December 2017. Total of 1, 478 very young participants, including 1, 059 ACS patients and 419 non-CAD subjects, were enrolled in the present study. Results Very young patients with ACS had higher AIP level compared with non-CAD participants (0.35 ± 0.30 vs 0.21 ± 0.33, P < 0.001). According to Gensini Score (GS) and number of lesion vessel, patients were divided into four groups, respectively. With the elevated GS score and number of lesion vessels, the AIP level increased gradually (P for trend all< 0.05). Multivariate logistic regression analyses suggested that AIP remained to be independently associated with the presence of ACS and was superior to traditional lipid profiles (for AIP, OR = 2.930, 95% CI = 1.855–4.627, P < 0.001; for total cholesterol, OR = 1.152, 95% CI = 1.048–1.266, P = 0.003; for triglyceride, OR = 1.078, 95% CI = 0.991–1.172, P = 0.079; for low-density lipoprotein cholesterol, OR = 1.046, 95% CI = 1.015–1.078, P < 0.001), after adjustment for other traditional confounders. Moreover, the prevalence of ACS, acute myocardial infarction, unstable angina pectoris and the value of GS were also elevated as AIP quartiles increased (P for trend < 0.001). Subgroup analysis based on gender revealed that AIP was only independently associated with the ACS risk in male. Conclusions AIP was independently associated with the presence and severity of ACS in very young patients in a gender-dependent manner, which might be superior to traditional lipid profiles

Study on Explosion Suppression Performance of Spherical Nonmetallic Materials

AbstractTaking horizontal shock tube as the main equipment in this paper, using chemical ignition and high voltage ignition as the ignition source to evaluate the flame wave propagation characteristics of spherical nonmetallic explosion-suppression materials and aluminium alloy explosion-suppression materials when the horizontal shock tube was filled with No. 93 gasoline and liquefied petroleum gas vapors. The trend of peak overpressure and the flame propagation speed was tested, and the mechanism of flame and overpressure propagation was analyzed in the experiment. The results show that the spherical nonmetallic materials are better than aluminium alloy explosion-suppression materials for peak overpressure and flame wave propagation velocity suppression

Electrostatic coupling in MoS₂/CuInP₂S₆ Ferroelectric vdW heterostructures

Ferroelectric van der Waals (vdW) heterostructure have recently emerged as a low-power, versatile device paradigm because it combines the great diversity of the 2D materials and the memory nature of ferroelectrics. The non-volatile field effect generated by the polarization bound charge is the pivotal factor for the device's performance. Unfortunately, microscopic studies on the interplay between polarization switching and electrostatic coupling at the heterojunction remain largely overlooked. Herein, the authors investigate the electrostatic coupling phenomena of vdW heterostructures consisting of semiconducting MoS2 and ferroelectric CuInP2S6. Significant charge injection accompanying the polarization reversal appears to be the governing field effect that modulates the electronic and photoluminescent properties of MoS2, as revealed by correlated ferroelectric domain, surface potential, and photoluminescence microscopies. Conversely, the photoactivity of the MoS2 also affects the polarization stability of CuInP2S6. This work provides direct microscopic insight into the mutual electrostatic interactions in vdW ferroelectric-semiconductor heterojunctions, which has broad implications for ferroelectric field-effect applications.This work was supported by the National Natural Science Foundation of China (No. 12074278), the Natural Science Foundation of the Jiangsu Higher Education Institution of China (20KJA140001), and the Priority Academic Program Development (PAPD) of Jiangsu Higher Education Institutions. L.Y. acknowledges the startup funds from Soochow University and Jiangsu Specially-Appointed Professors Program

Microglia-derived TNF-α contributes to RVLM neuronal mitochondrial dysfunction via blocking the AMPK–Sirt3 pathway in stress-induced hypertension

Abstract Background Neuroinflammation in the rostral ventrolateral medulla (RVLM) has been associated with the pathogenesis of stress-induced hypertension (SIH). Neuronal mitochondrial dysfunction is involved in many pathological and physiological processes. However, the impact of neuroinflammation on neuronal mitochondrial homeostasis and the involved signaling pathway in the RVLM during SIH are largely unknown. Methods The morphology and phenotype of microglia and the neuronal mitochondrial injury in vivo were analyzed by immunofluorescence, Western blot, RT-qPCR, transmission electron microscopy, and kit detection. The underlying mechanisms of microglia-derived tumor necrosis factor‐α (TNF-α) on neuronal mitochondrial function were investigated through in vitro and in vivo experiments such as immunofluorescence and Western blot. The effect of TNF-α on blood pressure (BP) regulation was determined in vivo via intra-RVLM microinjection of TNF-α receptor antagonist R7050. Results The results demonstrated that BP, heart rate (HR), renal sympathetic nerve activity (RSNA), plasma norepinephrine (NE), and electroencephalogram (EEG) power increased in SIH rats. Furthermore, the branching complexity of microglia in the RVLM of SIH rats decreased and polarized into M1 phenotype, accompanied by upregulation of TNF‐α. Increased neuronal mitochondria injury was observed in the RVLM of SIH rats. Mechanistically, Sirtuin 3 (Sirt3) and p-AMPK expression were markedly downregulated in both SIH rats and TNF-α–treated N2a cells. AMPK activator A769662 upregulated AMPK–Sirt3 signaling pathway and consequently reversed TNF-α–induced mitochondrial dysfunction. Microinjection of TNF-α receptor antagonist R7050 into the RVLM of SIH rats significantly inhibited the biological activities of TNF-α, increased p‐AMPK and Sirt3 levels, and alleviated neuronal mitochondrial injury, thereby reducing c-FOS expression, RSNA, plasma NE, and BP. Conclusions This study revealed that microglia-derived TNF-α in the RVLM impairs neuronal mitochondrial function in SIH possibly through inhibiting the AMPK–Sirt3 pathway. Therefore, microglia-derived TNF-α in the RVLM may be a possible therapeutic target for the intervention of SIH