Monetary Policy and Exchange Rate Regime: Proposal for a Small and Less Developed Economy

We investigate monetary policy under the assumption that a country’s capital market is “open” under the WTO framework while the exchange rate is fixed. Our purpose is to determine if it is possible in this case for the economy to maintain an effective monetary policy for stabilizing the domestic economy. For this, we suggest two institutional restrictions. Given the restrictions, we demonstrate within a macro-dynamic model that monetary policy can still be effective. The implication of such an institutional design for an exchange rate regime is also discussed with special reference to small and less development economies.open economy trilemma; macroeconomic stability; exchange rate regime

Interaction of a symmetrical α,α',δ,δ'-Tetramethyl-cucurbit[6]uril with Ln³⁺ : potential applications for isolation of lanthanides

The interaction of a symmetrical α,α′,δ,δ′-tetramethyl-cucurbit[6]uril (TMeQ[6]) with a series of lanthanide cations (Ln³⁺) was investigated in neutral water and in acidic solution. Analysis by single crystal X-ray diffraction revealed that different isomorphous families formed under different synthetic conditions. Such differences in the interaction between TMeQ[6] and Ln³⁺ could potentially be used for isolating heavier Ln³⁺ from their lighter counterparts in neutral solution, and lighter lanthanide cations from their heavier counterparts in acidic solution

Induced log-concavity of equivariant matroid invariants

Inspired by the notion of equivariant log-concavity, we introduce the concept of induced log-concavity for a sequence of representations of a finite group. For an equivariant matroid equipped with a symmetric group action or a finite general linear group action, we transform the problem of proving the induced log-concavity of matroid invariants to that of proving the Schur positivity of symmetric functions. We prove the induced log-concavity of the equivariant Kazhdan-Lusztig polynomials of $q$-niform matroids equipped with the action of a finite general linear group, as well as that of the equivariant Kazhdan-Lusztig polynomials of uniform matroids equipped with the action of a symmetric group. As a consequence of the former, we obtain the log-concavity of Kazhdan-Lusztig polynomials of $q$-niform matroids, thus providing further positive evidence for Elias, Proudfoot and Wakefield's log-concavity conjecture on the matroid Kazhdan-Lusztig polynomials. From the latter we obtain the log-concavity of Kazhdan-Lusztig polynomials of uniform matroids, which was recently proved by Xie and Zhang by using a computer algebra approach. We also establish the induced log-concavity of the equivariant characteristic polynomials and the equivariant inverse Kazhdan-Lusztig polynomials for $q$-niform matroids and uniform matroids.Comment: 36 page

The role of globular heads of the C1q receptor in HPV 16 E2-induced human cervical squamous carcinoma cell apoptosis is associated with p38 MAPK/JNK activation

BACKGROUND Human papillomavirus type 16 (HPV 16) E2 protein is a multifunctional DNA-binding protein. HPV 16 E2 regulates many biological responses, including DNA replication, gene expression, and apoptosis. The purpose of this study was to investigate the relationship among the receptor for globular heads of the human C1q (gC1qR) gene expression, HPV 16 E2 transfection and apoptosis regulation in human cervical squamous carcinoma cells (C33a and SiHa). METHODS gC1qR expression was examined in C33a and SiHa cells using real-time PCR and Western blot analysis. Apoptosis of C33a and SiHa cells was assessed by flow cytometry. C33a and SiHa cell viability, migration and proliferation were detected using the water-soluble tetrazolium salt (WST-1) assay, a transwell assay and 3H-thymidine incorporation into DNA (3H-TdR), respectively. RESULTS C33a and SiHa cells that were transfected with a vector encoding HPV 16 E2 displayed significantly increased gC1qR gene expression and p38 mitogen-activated protein kinase (p38 MAPK)/c-jun N-terminal kinase (JNK) activation as well as up-regulation of cellular apoptosis, which was abrogated by the addition of gC1qR small interfering RNA (siRNA). Furthermore, the changes in C33a and SiHa cell viability, migration and proliferation that were observed upon HPV 16 E2 transfection were abrogated by SB203580 (a p38 MAPK inhibitor) or SP600125 (a JNK inhibitor) treatment. CONCLUSION These data support a mechanism whereby HPV 16 E2 induces apoptosis by silencing the gC1qR gene or inhibiting p38 MAPK/JNK signalling in cervical squamous cell carcinoma.This study was supported by grants from the National Natural Science Foundation of China (No. 81000251) and the Nanjing Medical Science and Technique Development Foundation

Interaction effects of pseudospin-based magnetic monopoles and kinks in a doped dipolar superlattice gas

Magnetic monopoles and kinks are topological excitations extensively investigated in quantum spin systems, but usually they are studied in different setups. We explore the conditions for the coexistence and the interaction effects of these quasiparticles in the pseudospin chain of the atomic dipolar superlattice gas. In this chain, the magnetic kink is the intrinsic quasiparticle, and the particle/hole defect takes over the role of the north/south magnetic monopole, exerting monopolar magnetic fields to neighboring spins. A confinement effect between the monopole and kink is revealed, which renormalizes the dispersion of the kink. The corresponding dynamical deconfinement process is observed and arises due to the kink-antikink annihilation. The rich interaction effects of the two quasiparticles could stimulate corresponding investigations in bulk spin systems

Rational application of fructose-1,6-diphosphate: From the perspective of pharmacokinetics

Fructose-1,6-diphosphate (FDP), a glycolytic metabolite, has been reported to protect susceptible organs during hypoxia or ischemia. However, there is paucity of human data on its pharmacokinetics after being exogenously administered. In the current study, the preliminary pharmacokinetics of FDP given orally to humans was investigated, and no typical peak was observed in the serum drug-time curve. Then, the pharmacokinetic studies were performed following multiple doses of of FDP in rats, and the Caco-2 monolayer model was used to study the absorption of FDP in vitro. The results suggested that plasma FDP concentration was significantly increased after oral multiple doses of 180 mg kg-1 but not 90 mg kg-1 of FDP, and FDP was partly depleted during the absorption, which was supposed to be consumed by the intestinal epithelium cells. Thus, we conclude that a high dose of FDP should be orally administered in order to get an effective plasma level