2,716 research outputs found

    Predicting the epidemic threshold of the susceptible-infected-recovered model

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    Researchers have developed several theoretical methods for predicting epidemic thresholds, including the mean-field like (MFL) method, the quenched mean-field (QMF) method, and the dynamical message passing (DMP) method. When these methods are applied to predict epidemic threshold they often produce differing results and their relative levels of accuracy are still unknown. We systematically analyze these two issues---relationships among differing results and levels of accuracy---by studying the susceptible-infected-recovered (SIR) model on uncorrelated configuration networks and a group of 56 real-world networks. In uncorrelated configuration networks the MFL and DMP methods yield identical predictions that are larger and more accurate than the prediction generated by the QMF method. When compared to the 56 real-world networks, the epidemic threshold obtained by the DMP method is closer to the actual epidemic threshold because it incorporates full network topology information and some dynamical correlations. We find that in some scenarios---such as networks with positive degree-degree correlations, with an eigenvector localized on the high kk-core nodes, or with a high level of clustering---the epidemic threshold predicted by the MFL method, which uses the degree distribution as the only input parameter, performs better than the other two methods. We also find that the performances of the three predictions are irregular versus modularity

    Bis(μ-3-nitro­phthalato-κ2 O 1:O 2)bis­[(thio­urea-κS)zinc] dihydrate

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    In the title complex, [Zn2(C8H3NO6)2(CH4N2S)4]·2H2O, the carboxyl­ate groups of the 3-nitro­phthalate ligands coordinate in a bis-monodentate mode to the ZnII cations. This results in the formation of a centrosymmetric dimer containing two ZnII cations with distorted tetra­hedral geometries provided by the O atoms of two different 3-nitro­phthalate dianions and the S atoms of two non-equivalent coordinated thio­urea mol­ecules. The crystal structure exhibits N—H⋯O and O—H⋯O hydrogen bonds which link the dimers into a three-dimensional network

    Tired Light Denies the Big Bang

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    More and more problems related to Big Bang have been appeared in recent years. All the problems are due to the Doppler interpretation of redshift. The “tired light” theory, proposed in 1929 by Zwicky and most recently developed by Shao in 2013, gives a new explanation for redshift. The theory has shown that the redshift is induced from the energy loss of photons by the interaction with material particles on their journey through cosmological space. The basic principles related to the energy transfer are mainly the mass-energy equivalence and the Lorentz theory. Problems, such as super velocity, the horizon problem, the cosmological microwave background radiation, and Olbers’ paradox, vanish in the cosmological model of “tired light” theory. The model describes a boundless and timeless Cosmos

    Simple approach to estimating the van der Waals interaction between carbon nanotubes

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    The van der Waals (vdW) interactions between carbon nanotubes (CNTs) were studied based on the continuum Lennard-Jones model. It was found that all the vdW potentials between two arbitrary CNTs fall on the same curve when plotted in terms of certain reduced parameters, the well depth, and the equilibrium vdW gap. Based on this observation, an approximate approach is developed to obtain the vdW potential between two CNTs without time-consuming computations. The vdW potential estimated by this approach is close to that obtained from complex integrations. Therefore, the developed approach can greatly simplify the calculation of vdW interactions between CNTs

    The Analysis of the Properties of Bus Network Topology in Beijing Basing on Complex Networks

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    The transport network structure plays a crucial role in transport dynamics. To better understand the property of the bus network in big city and reasonably configure the bus lines and transfers, this paper seeks to take the bus network of Beijing as an example and mainly use space L and space P to analyze the network topology properties. The approach is applied to all the bus lines in Beijing which includes 722 lines and 5421 bus station. In the first phase of the approach, space L is used. The results show that the bus network of Beijing is a scale-free network and the degree of more than 99 percent of nodes is lower than 10. The results also show that the network is an assortative network with 46 communities. In a second phase, space P is used to analyze the property of transfer. The results show that the average transfer time of Beijing bus network which is 1.88 and 99.8 percent of arbitrary two pair nodes is reachable within 4 transfers

    Requirement of extracellular signal-regulated kinase/mitogen-activated protein kinase for long-term potentiation in adult mouse anterior cingulate cortex

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    Long-term potentiation (LTP) in the anterior cingulate cortex (ACC) is believed to be critical for higher brain functions including emotion, learning, memory and chronic pain. N-methyl-D-aspartate (NMDA) receptor-dependent LTP is well studied and is thought to be important for learning and memory in mammalian brains. As the downstream target of NMDA receptors, the extracellular signal-regulated kinase (ERK) in the mitogen-activated protein kinase (MAPK) cascade has been extensively studied for its involvement in synaptic plasticity, learning and memory in hippocampus. By contrast, the role of ERK in cingulate LTP has not been investigated. In this study, we examined whether LTP in ACC requires the activation of ERK. We found that P42/P44 MAPK inhibitors, PD98059 and U0126, suppressed the induction of cingulate LTP that was induced by presynaptic stimulation with postsynaptic depolarization (the pairing protocol). We also showed that cingulate LTP induced by two other different protocols was also blocked by PD98059. Moreover, we found that these two inhibitors had no effect on the maintenance of cingulate LTP. Inhibitors of c-Jun N-terminal kinase (JNK) and p38, other members of MAPK family, SP600125 and SB203850, suppressed the induction of cingulate LTP generated by the pairing protocol. Thus, our study suggests that the MAPK signaling pathway is involved in the induction of cingulate LTP and plays a critical role in physiological conditions
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