Comparative evaluation of procoagulant and proinflammatory markers in drug naive versus oral contraceptive pill’s (OCP’s) treated Polycystic Ovary Syndrome (PCOS) women.

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder of young women. There is a spectacular increase in the prevalence of PCOS all over world especially in Asia. The condition seems to be on rise in Kashmir valley although systemic studies on the subject are underway. First line of treatment is often the oral contraceptive pills (OCP’s) as most of these women attend to various gynaecologists and they desire menstrual regulation. Since there is plethora of data that PCOS women have evidence of enhanced markers of inflammation and indicators of coagulation. Therefore treatment with OCP’s may worsen the metabolic, inflammatory and coagulation parameters in this population. We undertook this study to investigate the effect of OCP treatment procoagulant and proinflammatory markers in women with PCOS. The results may therefore translate in to the clinical practice