6,718 research outputs found

    Economic Liberalization - A Stumbling Block in the Commercialization of Indigenous Calcium Silicide Technology

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    Indian ferro alloy industry is passing through one of its worst periods by the process of economic liberalization. Its production in our country is coming down mainly due to inadequate indigenous demand, non-availability of exports and high power cost as compared to other competing countries. The indigenous calcium silicide technology developed at National Metallurgical Laboratory; Jamshedpur could not be commercialized on account of thenew economic liberalization policy of Government of India

    Shape-invariant quantum Hamiltonian with position-dependent effective mass through second order supersymmetry

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    Second order supersymmetric approach is taken to the system describing motion of a quantum particle in a potential endowed with position-dependent effective mass. It is shown that the intertwining relations between second order partner Hamiltonians may be exploited to obtain a simple shape-invariant condition. Indeed a novel relation between potential and mass functions is derived, which leads to a class of exactly solvable model. As an illustration of our procedure, two examples are given for which one obtains whole spectra algebraically. Both shape-invariant potentials exhibit harmonic-oscillator-like or singular-oscillator-like spectra depending on the values of the shape-invariant parameter.Comment: 16 pages, 5 figs; Present e-mail of AG: [email protected]

    Phosphorylation of pRb: mechanism for RB pathway inactivation in MYCN-amplified retinoblastoma.

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    A small, but unique subgroup of retinoblastoma has been identified with no detectable mutation in the retinoblastoma gene (RB1) and with high levels of MYCN gene amplification. This manuscript investigated alternate pathways of inactivating pRb, the encoded protein in these tumors. We analyzed the mutation status of the RB1 gene and MYCN copy number in a series of 245 unilateral retinoblastomas, and the phosphorylation status of pRb in a subset of five tumors using immunohistochemistry. There were 203 tumors with two mutations in RB1 (RB1(-/-) , 83%), 29 with one (RB1(+/-) , 12%) and 13 with no detectable mutations (RB1(+/+) , 5%). Eighteen tumors carried MYCN amplification between 29 and 110 copies: 12 had two (RB1(-/-) ) or one RB1 (RB1(+/-) ) mutations, while six had no mutations (RB1(+/+) ). Immunohistochemical staining of tumor sections with antibodies against pRb and phosphorylated Rb (ppRb) displayed high levels of pRb and ppRb in both RB1(+/+) and RB1(+/-) tumors with MYCN amplification compared to no expression of these proteins in a classic RB1(-/-) , MYCN-low tumor. These results establish that high MYCN amplification can be present in retinoblastoma with or without coding sequence mutations in the RB1 gene. The functional state of pRb is inferred to be inactive due to phosphorylation of pRb in the MYCN-amplified retinoblastoma without coding sequence mutations. This makes inactivation of RB1 by gene mutation or its protein product, pRb, by protein phosphorylation, a necessary condition for initiating retinoblastoma tumorigenesis, independent of MYCN amplification

    Explainable deep learning for insights in El Ni\~no and river flows

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    The El Ni\~no Southern Oscillation (ENSO) is a semi-periodic fluctuation in sea surface temperature (SST) over the tropical central and eastern Pacific Ocean that influences interannual variability in regional hydrology across the world through long-range dependence or teleconnections. Recent research has demonstrated the value of Deep Learning (DL) methods for improving ENSO prediction as well as Complex Networks (CN) for understanding teleconnections. However, gaps in predictive understanding of ENSO-driven river flows include the black box nature of DL, the use of simple ENSO indices to describe a complex phenomenon and translating DL-based ENSO predictions to river flow predictions. Here we show that eXplainable DL (XDL) methods, based on saliency maps, can extract interpretable predictive information contained in global SST and discover SST information regions and dependence structures relevant for river flows which, in tandem with climate network constructions, enable improved predictive understanding. Our results reveal additional information content in global SST beyond ENSO indices, develop understanding of how SSTs influence river flows, and generate improved river flow prediction, including uncertainty estimation. Observations, reanalysis data, and earth system model simulations are used to demonstrate the value of the XDL-CN based methods for future interannual and decadal scale climate projections

    On Deterministic Sketching and Streaming for Sparse Recovery and Norm Estimation

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    We study classic streaming and sparse recovery problems using deterministic linear sketches, including l1/l1 and linf/l1 sparse recovery problems (the latter also being known as l1-heavy hitters), norm estimation, and approximate inner product. We focus on devising a fixed matrix A in R^{m x n} and a deterministic recovery/estimation procedure which work for all possible input vectors simultaneously. Our results improve upon existing work, the following being our main contributions: * A proof that linf/l1 sparse recovery and inner product estimation are equivalent, and that incoherent matrices can be used to solve both problems. Our upper bound for the number of measurements is m=O(eps^{-2}*min{log n, (log n / log(1/eps))^2}). We can also obtain fast sketching and recovery algorithms by making use of the Fast Johnson-Lindenstrauss transform. Both our running times and number of measurements improve upon previous work. We can also obtain better error guarantees than previous work in terms of a smaller tail of the input vector. * A new lower bound for the number of linear measurements required to solve l1/l1 sparse recovery. We show Omega(k/eps^2 + klog(n/k)/eps) measurements are required to recover an x' with |x - x'|_1 <= (1+eps)|x_{tail(k)}|_1, where x_{tail(k)} is x projected onto all but its largest k coordinates in magnitude. * A tight bound of m = Theta(eps^{-2}log(eps^2 n)) on the number of measurements required to solve deterministic norm estimation, i.e., to recover |x|_2 +/- eps|x|_1. For all the problems we study, tight bounds are already known for the randomized complexity from previous work, except in the case of l1/l1 sparse recovery, where a nearly tight bound is known. Our work thus aims to study the deterministic complexities of these problems

    Nonsingular potentials from excited state factorization of a quantum system with position dependent mass

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    The modified factorization technique of a quantum system characterized by position-dependent mass Hamiltonian is presented. It has been shown that the singular superpotential defined in terms of a mass function and a excited state wave function of a given position-dependent mass Hamiltonian can be used to construct non-singular isospectral Hamiltonians. The method has been illustrated with the help of a few examples.Comment: Improved version accepted in J. Phys.

    Absorption of Electro-magnetic Waves in a Magnetized Medium

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    In continuation to our earlier work, in which the structure of the vacuum polarisation tensor in a medium was analysed in presence of a background electro-magnetic field, we discuss the absorptive part of the vacuum polarization tensor. Using the real time formalism of finite temperature field theory we calculate the absorptive part of 1-loop vacuum polarisation tensor in the weak field limit (eB<m2eB < m^2). Estimates of the absorption probability are also made for different physical conditions of the background medium.Comment: 9 Pages. One figure. LaTe

    Optical Activity From Extra Dimension

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    Optical activity, like Faraday effect, is a rotation of the plane of polarization of propagating light in a medium and can be attributed to different sources with distinct signatures. In this note we discuss the effect of optical activity {\it{in vacuum}} due to Kaluza-Klein scalar field Ď•\phi, in the presence of an external electro-magnetic field. The astrophysical implication of this effect is indicated. We also point out the possibility of observing the same in laboratory conditions.Comment: Four Page

    Transport and Magnetic Properties of R1-xAxCoO3 (R=La, Pr and Nd; A=Ba, Sr and Ca)

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    Transport and magnetic measurements have been carried out on perovskite Co-oxides R1-xAxCoO3 (R=La, Pr, and Nd; A=Ba, Sr and Ca; 0<x<0.5: All sets of the R and A species except Nd1-xBaxCoO3 have been studied.). With increasing the Sr- or Ba-concentration x, the system becomes metallic ferromagnet with rather large magnetic moments. For R=Pr and Nd and A=Ca, the system approaches the metal- insulator phase boundary but does not become metallic. The magnetic moments of the Ca-doped systems measured with the magnetic field H=0.1 T are much smaller than those of the Ba- and Sr-doped systems. The thermoelectric powers of the Ba- and Sr-doped systems decrease from large positive values of lightly doped samples to negative ones with increasing doping level, while those of Ca-doped systems remain positive. These results can be understood by considering the relationship between the average ionic radius of R1-xAx and the energy difference between the low spin and intermediate spin states. We have found the resistivity-anomaly in the measurements of Pr1-xCaxCoO3 under pressure in the wide region of x, which indicates the existence of a phase transition different from the one reported in the very restricted region of x~0.5 at ambient pressure [Tsubouchi et al. Phys. Rev. B 66 (2002) 052418.]. No indication of this kind of transition has been observed in other species of R.Comment: 9 pages, 8 figures. J. Phys. Soc. Jpn. 72 (2003) No.
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