Efeito do aquecimento sobre acidez e oxidação em óleo de polpa de macaúba.

Este trabalho objetivou avaliar características químicas do óleo de polpa bruto e refinado antes e após ensaio termoxidativo

Integrating Community-Based Interventions to Reverse the Convergent TB/HIV Epidemics in Rural South Africa.

The WHO recommends integrating interventions to address the devastating TB/HIV co-epidemics in South Africa, yet integration has been poorly implemented and TB/HIV control efforts need strengthening. Identifying infected individuals is particularly difficult in rural settings. We used mathematical modeling to predict the impact of community-based, integrated TB/HIV case finding and additional control strategies on South Africa's TB/HIV epidemics. We developed a model incorporating TB and HIV transmission to evaluate the effectiveness of integrating TB and HIV interventions in rural South Africa over 10 years. We modeled the impact of a novel screening program that integrates case finding for TB and HIV in the community, comparing it to status quo and recommended TB/HIV control strategies, including GeneXpert, MDR-TB treatment decentralization, improved first-line TB treatment cure rate, isoniazid preventive therapy, and expanded ART. Combining recommended interventions averted 27% of expected TB cases (95% CI 18-40%) 18% HIV (95% CI 13-24%), 60% MDR-TB (95% CI 34-83%), 69% XDR-TB (95% CI 34-90%), and 16% TB/HIV deaths (95% CI 12-29). Supplementing these interventions with annual community-based TB/HIV case finding averted a further 17% of TB cases (44% total; 95% CI 31-56%), 5% HIV (23% total; 95% CI 17-29%), 8% MDR-TB (68% total; 95% CI 40-88%), 4% XDR-TB (73% total; 95% CI 38-91%), and 8% TB/HIV deaths (24% total; 95% CI 16-39%). In addition to increasing screening frequency, we found that improving TB symptom questionnaire sensitivity, second-line TB treatment delays, default before initiating TB treatment or ART, and second-line TB drug efficacy were significantly associated with even greater reductions in TB and HIV cases. TB/HIV epidemics in South Africa were most effectively curtailed by simultaneously implementing interventions that integrated community-based TB/HIV control strategies and targeted drug-resistant TB. Strengthening existing TB and HIV treatment programs is needed to further reduce disease incidence

Geodetic deformation Across the Central Apennines from GPS Data in the time span 1999-2003

Abstract During the time span 1999-2003 was set up and repeatedly surveyed a not permanent GPS network located across one of the highest seismic areas of the central Apennines (Italy). The Central Apennine Geodetic Network (CA-GeoNet), extends across Umbria, Abruzzo, Marche and Lazio regions, in an area of ∼180x130 km, from Tyrrhenian to the Adriatic sea. It consists in 125 GPS stations distributed at 3-5 km average grid and includes 7 permanent GPS stations operated by the Italian Space Agency (ASI) and the Istituto Nazionale di Geofisica and Vulcanologia (INGV). With the aim to estimate the active strain rate across this part of the chain, the GPS sites have been located on the main geological units of the area and across the typical basin and range structures, related with the main seismogenic faults. In this paper we show the network and the first results obtained for a subset of 23 stations that have been occupied at least during three repeated campaigns, in the time span 1999-2003. Data analysis, performed by Bernese 4.2 software, shows an extensional rate normal to the chain, in agreement with geological and seismic data. The strain rates in the inner chain are ranging from 12x10-9±11yr-1 to 16x10-9±11yr-1 and from -14x10-9±11yr-1 to -3x10-9±11yr-1. This result provides an improved estimation of the ongoing deformation of this area with respect to previous studies and is in agreement with the style of deformation inferred from seismicity and with the features of the main seismogenic sources from recent geological and seismological investigations

Data analysis of Permanent GPS networks in Italy and surrounding region: application of a distributed processing approach

We describe the procedures used to combine into a uniform velocity solution the observations of more than 80 continuous GPS stations operating in the central Mediterranean in the 1998-2004 time interval. We used a distributed processing approach, which makes efficient use of computer resources, while producing velocity estimates for all stations in one common reference frame, allowing for an effective merging of all the observations into a self-consistent network solution. We describe the CGPS data archiving and processing procedures, and provide main results in terms of position time-series and velocities for all stations that observed more than three years. We computed horizontal and vertical velocities accounting for the seasonal (annual and semi-annual) signals, and considering the off-sets in the coordinate time-series caused by station equipment changes. Weighted post-fit RMS of the north, east and vertical velocity components are in the range of 1.57-2.08 mm, 1.31-3.28 mm, and 3.60-7.24 mm, respectively, which are reduced by solving for seasonal signals in the velocity estimates. The annual and semi-annual signals in the height components, with amplitudes up to 4.8 mm, are much stronger than those in the horizontal components. The mean amplitudes of annual and semi-annual signals are within 0.18-0.47 mm, 0.23-0.52 mm and 0.55-1.92 mm in the north, east and vertical components, respectively

Quantifying transmission of clostridium difficile within and outside healthcare settings

To quantify the effect of hospital and community-based transmission and control measures on Clostridium difficile infection (CDI), we constructed a transmission model within and between hospital, community, and long-term care-facility settings. By parameterizing the model from national databases and calibrating it to C. difficile prevalence and CDI incidence, we found that hospitalized patients with CDI transmit C. difficile at a rate 15 (95% CI 7.2–32) times that of asymptomatic patients. Long-term care facility residents transmit at a rate of 27% (95% CI 13%–51%) that of hospitalized patients, and persons in the community at a rate of 0.1% (95% CI 0.062%–0.2%) that of hospitalized patients. Despite lower transmission rates for asymptomatic carriers and community sources, these transmission routes have a substantial effect on hospital-onset CDI because of the larger reservoir of hospitalized carriers and persons in the community. Asymptomatic carriers and community sources should be accounted for when designing and evaluating control interventions

THE EVOLUTION OF THE MARCHE REGION COASTAL ZONE (ADRIATIC SEA) AND THE CLIMATE CHANGE

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