The Immune System

Modern biotherapy has been in use for some 30 years. The first types of biotherapy were nonspecific stimulators of the immune response, but advances in genetic engineering are allowing the mass production of pure biological products which are now being tested as pharmaceutical agents. Biotherapy connotes the administration of products (1) that are coded by the mammalian genome; (2) that modify the expression of mammalian genes; or (3) that stimulate the immune system. In this chapter the discussion of the immune system will be limited primarily to topics relevant to cancer or autoimmune diseases. Because understanding the new biological agents requires an understanding of both the immune response and the molecular basis of oncogenesis, this chapter first presents a summary of the structure and function of the immune system. Following a discussion of immune responses, and the cells involved in these responses, will be a discussion on the current concepts of oncogenesis, particularly oncogenes and growth factors. Because research efforts are beginning to identify many biological proteins as having a role in autoimmune and other diseases, a brief introduction to autoimmune diseases is also included at the end of the chapter

Attracted but Unsatisfied: The Effects of Arousing Content on Television Consumption Choices

This paper investigates experimentally the effects of arousing content on viewing choices and satisfaction in television consumption. We test the hypothesis that the portrayal of arousing content combines high attraction and low satisfaction and is thus responsible for suboptimal choices. In our experiment, subjects can choose among three programs during a viewing session. In the experimental condition, one of the three programs portrays a violent verbal conflict, whereas in the control condition the same program portrays a calm debate. A post-experimental questionnaire is used to assess subjects' satisfaction with the programs and the overall viewing experience. The results support the hypothesis: the presence of arousing content causes sub- jects to watch more of a given program, although they experience lower content-specific and overall satisfaction. Arousing contents also significantly increase the discrepancy between actual and desired viewing.Rational Choice, Audience, Television, Satisfaction, Arousing content, Laboratory Experiments.

Localisation vs. globalisation of typical products and experiential consumption

The transformations taking place in the world economy can facilitate integration processes, both on a horizontal and vertical scale, and can be an opportunity for all businesses, of whatever size and sector. Nowadays, in this globalized economy consumers seem to be more and more interested in buying artisan products as synonymous of quality, tradition, culture and environment respect. The aim of this paper is to analyse and define characteristic local products in the framework of an economic model of experience. In this perspective, once having highlighted the strengths and weaknesses of this particular supply system, we intend to stretch the conceptual scheme of the typical product to the point of including in the concept of supply the relative experience connected to such specificity to be found only in their places of origin.Globalisation, local markets, typical products, experience economy.

Autothermal Reforming of Methane with Integrated CO2 Capture in a Novel Fluidized Bed Membrane Reactor. Part 2 Comparison of Reactor Configurations

The reactor performance of two novel fluidized bed membrane reactor configurations for hydrogen production with integrated CO2 capture by autothermal reforming of methane (experimentally investigated in Part 1) have been compared using a phenomenological reactor model over a wide range of operating conditions (temperature, pressure, H2O/CH4 ratio and membrane area). It was found that the methane combustion configuration (where part of the CH4 is combusted in situ with pure O2) largely outperforms the hydrogen combustion concept (oxidative sweeping combusting part of the permeated H2) at low H2O/CH4 ratios (<2) due to in situ steam production, but gives a slightly lower hydrogen production rate at higher H2O/CH4 ratios due to dilution with combustion products. The CO selectivity was always much lower with the methane combustion configuration. Whether the methane combustion or hydrogen combustion configuration is preferred depends strongly on the economics associated with the H2O/CH4 ratio

Fixed Implant Rehabilitations of the Edentulous Jaw

Wismeyer, D. [Promotor]Belser, U.C. [Promotor