Morphometry Results of Formed Osteodefects When Using Nanocrystalline CeO2 in the Early Stages of Regeneration

This paper studies of the use of nanocrystalline cerium dioxide with artificially formed bone tissue defects. The results of morphometry confirmed the antialterative effect in the early stages of the reparative process of damaged bone tissue. When using calcium hydroxide with nanodispersed cerium dioxide, the nature of osteogenesis should be characterized as activated. In case of damage to the dentin of the roots of the teeth, dentinogenesis in presence of CeO2 occurs with the formation of a combined dentin and bone regenerates. Little or no studies of dentinogenesis in presence of CeO2 were performed by other researchers

Diffuse Reflectance Spectroscopy of the Oral Mucosa: In Vivo Experimental Validation of the Precancerous Lesions Early Detection Possibility

This article is devoted to the experimental validation of the possibility of early detection of precancerous lesions in the oral mucosa in vivo using diffuse reflectance spectroscopy in the wavelength range from 360 to 1000 nm. During the study, a sample of 119 patients with precancerous lesions has been collected and analyzed. As a result of the analysis, the most informative wavelength ranges were determined, in which the maximum differences in the backscattering spectra of lesions and intact tissues were observed, methods for automatic classification of backscattering spectra of the oral mucosa were studied, sensitivity and specificity values, achievable using diffuse reflectance spectroscopy for detecting hyperkeratosis on the tongue ventrolateral mucosa surface and buccal mucosa, were evaluated. As a result of preliminary experimental studies in vivo, the possibility of automatic detection of precancerous lesions of the oral mucosa surface using diffuse reflectance spectroscopy in the wavelength range from 500 to 900 nm with an accuracy of at least 75 percent has been shown

Содержание фенольных соединений в листьях Platanthera bifolia из естественной и трансформированных экосистем на разных стадиях развития орхидеи

The representatives of the family Orchidaceae Juss. are often used as a source of natural antioxidants, including phenolic compounds, which play an important role in plant resistance under stressful conditions. This study investigates the content of lipid peroxidation products and soluble phenolic compounds in flowering plants of Platanthera bifolia (L.) Rich. growing in natural (forest park) and transformed (fly ash dumps of Thermal Power Stations) ecosystems of the Middle Urals, Russia, as well as the content of flavonoids at different stages of orchid development. Research has shown that in disturbed habitats, P. bifolia is capable of forming abundant populations containing a significant portion of the flowering plants. Additionally, flowering orchids from fly ash dumps contained an average 20 % more lipid peroxidation products, which indicated a shift in the redox balance towards oxidative processes. An increase by 2.4 times on average in the content of phenolic compounds, particularly flavonoids, was observed at all developmental stages of the plants growing in the transformed ecosystems. Regardless of the growing conditions, the non-flowering mature individuals were characterized by a minimum content of flavonoids, probably due to pre-generative metabolic restructuring. Yet, in the period of orchid blooming, the flavonoid content in their leaves increased again in all study sites. At the same time, the flavonoid proportion of the total soluble phenolic compounds was 42 % in the natural habitat, increasing to 66 % on average in the transformed ecosystems. Thus, flavonoids are involved in the protective adaptive responses of P. bifolia, not only ensuring the survival of this orchid but also contributing to the implementation of its ontogenetic programПредставители семейства Orchidaceae Juss. нередко являются источником природных антиоксидантов, к числу которых относятся фенольные соединения, играющие важную роль в формировании устойчивости растений к стрессовым факторам. Изучено содержание продуктов перекисного окисления липидов (ПОЛ) и растворимых фенольных соединений у генеративных особей Platanthera bifolia (L.) Rich., произрастающих в естественной (лесопарк) и трансформированных (золоотвалы ГРЭС) экосистемах Среднего Урала, а также содержание флавоноидов в листьях орхидеи на разных стадиях ее развития. Обнаружено, что в нарушенных местообитаниях P. bifolia способна формировать ценопопуляции с высокой численностью и значительным вкладом в возрастной спектр генеративных особей. При этом цветущие орхидеи с золоотвалов содержали в среднем на 20 % больше продуктов ПОЛ, что свидетельствует о сдвиге редокс-баланса в сторону окислительных процессов. Кроме того, у растений, произрастающих в трансформированных экосистемах, наблюдалось увеличение содержания фенольных соединений, в частности флавоноидов (в среднем в 2,4 раза), на всех изученных стадиях. Независимо от условий произрастания виргинильные особи характеризовались минимальным содержанием флавоноидов, вероятно, из-за метаболических перестроек в период закладки генеративных органов. В период цветения количество флавоноидов в листьях орхидеи снова увеличивалось на всех участках. При этом доля флавоноидов от общего содержания фенольных соединений возрастала от 42 % в естественном фитоценозе до 66 % в среднем в трансформированных экосистемах. Сделано заключение, что флавоноиды участвуют в защитно-приспособительных реакциях P. bifolia, не только обеспечивая выживание этой орхидеи, но и способствуя реализации ее онтогенетической программ

Measurement of pseudorapidity distributions of charged particles in proton-proton collisions at sqrt(s) = 8 TeV by the CMS and TOTEM experiments

Pseudorapidity ( $\eta$ ) distributions of charged particles produced in proton–proton collisions at a centre-of-mass energy of 8 $~\text {TeV}$ are measured in the ranges $|\eta | < 2.2$ and $5.3 < |\eta | < 6.4$ covered by the CMS and TOTEM detectors, respectively. The data correspond to an integrated luminosity of $\mathcal {L} = 45 \mu {\mathrm {b}}^{-1}$ . Measurements are presented for three event categories. The most inclusive category is sensitive to 91–96 % of the total inelastic proton–proton cross section. The other two categories are disjoint subsets of the inclusive sample that are either enhanced or depleted in single diffractive dissociation events. The data are compared to models used to describe high-energy hadronic interactions. None of the models considered provide a consistent description of the measured distributions