Fluorescent carbon quantum dots for effective tumor diagnosis: A comprehensive review

The Fluorescent Carbon Quantum Dots (FCQDs) have been extensively explored for medical applications. Primarily, the research concentrated on diagnosis, imaging, and alternative therapeutics for various diseases. The FCQDs, a class of new-generation carbon nanoparticles with a size of less than 10 nm, demonstrate a quantum confinement effect. They have an atomic nature and inherent features like high photostability, variable photoluminescence (PL), high biocompatibility, and good water solubility. All these properties with minimum invasiveness have made quantum dots grab the spotlight in cancer diagnosis. The review introduces tunable fluorescence properties of quantum dots and provides a brief classification of FCQDs. Furthermore, the recent advances of FCQDs for tumor imaging and their refinements for futuristic applications are highlighted

Ultrahigh sensitive graphene oxide/conducting polymer composite based biosensor for cholesterol and bilirubin detection

Methods for detecting life-threatening diseases like cardiac arrest and arrhythmias are urgently required that are affordable and selective. The creation of nanocomposite based on graphene oxide, zinc oxide, polypyrrole, and polyaniline is one embodiment of the current disclosure. The nanocomposite of the present invention has highly enhanced the detection sensitivity of cholesterol and bilirubin. The dispersion of components in 1 (M) sulphuric acid is used to generate nanocomposite using the direct mixing technique. Glassy carbon electrodes are employed as the substrate material in the fabrication of nanocomposite-based biosensors. The sensor has demonstrated sensitivity of 0.92 μA μM−1 cm−2 and 0.2 μA μM−1 cm−2 for the detection of cholesterol and bilirubin, respectively. The innovative technology has enhanced lower detection limits, lower quantification limits, and good selectivity, among other things. In comparison to existing reports, the developed sensor has demonstrated greater sensitivity for the detection of cholesterol and bilirubin. As a result, the composite platform is ideal for the creation of high-sensitivity biosensors for a wide range of biomarkers