Sodium hydroxide pretreatment as an effective approach to reduce the dye/holes recombination reaction in P-Type DSCs

We report the synthesis of a novel squaraine dye (VG21-C12) and investigate its behavior as p-type sensitizer for p-type Dye-Sensitized Solar Cells. The results are compared with O4-C12, a well-known sensitizer for p-DSC, and sodium hydroxide pretreatment is described as an effective approach to reduce the dye/holes recombination. Various variable investigation such as dipping time, dye loading, photocurrent, and resulting cell efficiency are also reported. Electrochemical impedance spectroscopy (EIS) was utilized for investigating charge transport properties of the different photoelectrodes and the recombination phenomena that occur at the (un)modified electrode/electrolyte interface

Hypersensitive tunable Josephson escape sensor for gigahertz astronomy

Sensitive photon detection in the gigahertz band constitutes the cornerstone to study different phenomena in astronomy, such as radio burst sources, galaxy formation, cosmic microwave background, axions, comets, gigahertz-peaked spectrum radio sources and supermassive black holes. Nowadays, state of the art detectors for astrophysics are mainly based on transition edge sensors and kinetic inductance detectors. Overall, most sensible nanobolometers so far are superconducting detectors showing a noise equivalent power (NEP) as low as 2x10-20 W/Hz1/2. Yet, fast thermometry at the nanoscale was demonstrated as well with Josephson junctions through switching current measurements. In general, detection performance are set by the fabrication process and limited by used materials. Here, we conceive and demonstrate an innovative tunable Josephson escape sensor (JES) based on the precise current control of the temperature dependence of a fully superconducting one-dimensional nanowire Josephson junction. The JES might be at the core of future hypersensitive in situ-tunable bolometers or single-photon detectors working in the gigahertz regime. Operated as a bolometer the JES points to a thermal fluctuation noise (TFN) NEP_TFN 1x10-25 W/Hz1/2, which as a calorimeter bounds the frequency resolution above 2 GHz, and resolving power below 40 at 50 GHz, as deduced from the experimental data. Beyond the obvious applications in advanced ground-based and space telescopes for gigahertz astronomy, the JES might represent a breakthrough in several fields of quantum technologies ranging from subTHz communications and quantum computing to cryptography and quantum key distribution.Comment: 14 pages, 8 figure

MICROWAVE-ASSISTED BRUCITE AND TALC REACTIONS WITH CO2 AS A PROXY FOR CARBON CAPTURE AND STORAGE BY SERPENTINE

In the last decades many studies have been focusing on Carbon Capture and Storage (CCS) to find a possible remedy to reduce the large increase of anthropogenic carbon dioxide (CO ). Mineral Carbonation (MC) is a potential solution for almost irreversible chemical long-term CCS. It concerns the combination of CaO and MgO with CO forming spontaneously and exothermically dolomite and magnesite. However, kinetic barriers pose sever limitations for the practical exploitation of this reaction. High fractions of MgO are available in silicates such as olivine, orthopyroxene, clinopyroxene and serpentine. To date, data reported that serpentine polymorphs, above all antigorite, is an excellent candidate for fixing the CO as the reaction efficiency is approximately 92% compared to lizardite (40%) and olivine (66%). This is due to the surface reactivity of approximately 18.7 m /g for the dehydrated antigorite compared to10.8 m /g for dehydrated lizardite and 4.6 m /g for olivine. The microwave assisted process for CCS is an innovative technology that can be employed to catalyze the reaction through thermal and non-thermal mechanisms. Some pioneering tests of direct carbonation by microwave hydrothermal equipment have been performed on olivine, lizardite and chrysotile powders [1] but not on antigorite. The structure of serpentine is characterized by corrugated stacked layers of silica and brucite. For this reason, MC involves dissolution of SiO layers, dissolution/dehydration of Mg(OH) layers, and precipitation of magnesium carbonate. To address the chemical response of the single phases, experiments have been performed by both a local microwave-source acting locally on a specific crystal surface and a volume source interacting with an ensemble of grains on synthetic powders and single crystals of pure brucite and talc. In a second step, treatments have been extended to chrysotile, lizardite and antigorite. A characterization of the mechanism and kinetics were performed by scanning probe microscopy on the surface of single crystals phases, supported by Raman spectroscopy and by Scanning and Transmission Electron Microscopy study performed on micro- and nano-sized grains. [1] White, et al. Reaction mechanisms of magnesium silicates with carbon dioxide in microwave fields. Final Report to the U.S. Department ofEnergy, National Energy Technology Laboratory (2004

Development of highly sensitive nanoscale transition edge sensors for gigahertz astronomy and dark matter search

Terahertz and sub-terahertz band detection has a key role both in fundamental interactions physics and technological applications, such as medical imaging, industrial quality control and homeland security. In particular, transition edge sensors (TESs) and kinetic inductance detectors (KIDs) are the most employed bolometers and calorimeters in the THz and sub-THz band for astrophysics and astroparticles research. Here, we present the electronic, thermal and spectral characterization of an aluminum/copper bilayer sensing structure that, thanks to its thermal properties and a simple miniaturized design, could be considered a perfect candidate to realize an extremely sensitive class of nanoscale TES (nano-TES) for the giga-therahertz band. Indeed, thanks to the reduced dimensionality of the active region and the efficient Andreev mirror (AM) heat confinement, our devices are predicted to reach state-of-the-art TES performance. In particular, as a bolometer the nano-TES is expected to have a noise equivalent power (NEP) of $5\times10^{-20}$ W/$\sqrt{\mathrm{Hz}}$ and a relaxation time of $\sim 10$ ns for the sub-THz band, typical of cosmic microwave background studies. When operated as single-photon sensor, the devices are expected to show a remarkable frequency resolution of 100 GHz, pointing towards the necessary energy sensitivity requested in laboratory axion search experiments. Finally, different multiplexing schemes are proposed and sized for imaging applications.Comment: 12 page, 7 figure

Phylogeography and population genetic structure of the European roe deer in Switzerland following recent recolonization

In the early 1800s, the European roe deer (Capreolus capreolus) was probably extirpated from Switzerland, due to overhunting and deforestation. After a federal law was enacted in 1875 to protect lactating females and young, and limiting the hunting season, the roe deer successfully recovered and recolonized Switzerland. In this study, we use mitochondrial DNA and nuclear DNA markers to investigate the recolonization and assess contemporary genetic structure in relation to broad topographic features, in order to understand underlying ecological processes, inform future roe deer management strategies, and explore the opportunity for development of forensic traceability tools. The results concerning the recolonization origin support natural, multidirectional immigration from neighboring countries. We further demonstrate that there is evidence of weak genetic differentiation within Switzerland among topographic regions. Finally, we conclude that the genetic data support the recognition of a single roe deer management unit within Switzerland, within which there is a potential for broad‐scale geographic origin assignment using nuclear markers to support law enforcement

Citron Kinase Deficiency Leads to Chromosomal Instability and TP53-Sensitive Microcephaly

Mutations in citron (CIT), leading to loss or inactivation of the citron kinase protein (CITK), cause primary microcephaly in humans and rodents, associated with cytokinesis failure and apoptosis in neural progenitors. We show that CITK loss induces DNA damage accumulation and chromosomal instability in both mammals and Drosophila. CITK-deficient cells display "spontaneous" DNA damage, increased sensitivity to ionizing radiation, and defective recovery from radiation-induced DNA lesions. In CITK-deficient cells, DNA double-strand breaks increase independently of cytokinesis failure. Recruitment of RAD51 to DNA damage foci is compromised by CITK loss, and CITK physically interacts with RAD51, suggesting an involvement of CITK in homologous recombination. Consistent with this scenario, in doubly CitK and Trp53 mutant mice, neural progenitor cell death is dramatically reduced; moreover, clinical and neuroanatomical phenotypes are remarkably improved. Our results underscore a crucial role of CIT in the maintenance of genomic integrity during brain development

Phylogeography and population genetic structure of the European roe deer in Switzerland following recent recolonization

n the early 1800s, the European roe deer (Capreolus capreolus) was probably extirpated from Switzerland, due to overhunting and deforestation. After a federal law was en-acted in 1875 to protect lactating females and young, and limiting the hunting season, the roe deer successfully recovered and recolonized Switzerland. In this study, we use mitochondrial DNA and nuclear DNA markers to investigate the recolonization and as-sess contemporary genetic structure in relation to broad topographic features, in order to understand underlying ecological processes, inform future roe deer management strategies, and explore the opportunity for development of forensic traceability tools. The results concerning the recolonization origin support natural, multidirectional immi-gration from neighboring countries. We further demonstrate that there is evidence of weak genetic differentiation within Switzerland among topographic regions. Finally, we conclude that the genetic data support the recognition of a single roe deer management unit within Switzerland, within which there is a potential for broad- scale geographic origin assignment using nuclear markers to support law enforcement

Regional spread of an atypical ESBL-producing Escherichia coli ST131H89 clone among different human and environmental reservoirs in Western Switzerland

We describe the inter-regional spread of a novel ESBL-producing Escherichia coli subclone (ST131H89) in long-term care facility residents, general population, and environmental water sources in Western Switzerland between 2017 and 2020. The study highlights the importance of molecular surveillance for tracking emerging antibiotic-resistant pathogens in healthcare and community settings