Insidious Unilateral Vision Loss (PowerPoint)

Poor depth perception and vision ODA 47-year old female with a 4-month history of self-reported shadowy vision and poor depth perception OD. Previous history significant for rheumatoid arthritis, diabetes mellitus and hypothyroidism. Contributory: A 10-year history of smoking and exposure to anti-rheumatic agents.VA: 20/100, improving to 20/60 with pinhole and subsequent decline to 20/200 OD, 20/25 OS; Color plates: 2/8 OD, 7/8 OS; RAPD ODMRILymphocytic infiltration of dura from right optic nerve; Inflammation and fibrotic changes of right optic nerveIV steroids; Corticosteroids; SurgeryAttache

Insidious Unilateral Vision Loss

Poor depth perception and vision ODA 47-year old female with a 4-month history of self-reported shadowy vision and poor depth perception OD. Previous history significant for rheumatoid arthritis, diabetes mellitus and hypothyroidism. Contributory: A 10-year history of smoking and exposure to anti-rheumatic agents.VA: 20/100, improving to 20/60 with pinhole and subsequent decline to 20/200 OD, 20/25 OS; Color plates: 2/8 OD, 7/8 OS; RAPD ODMRILymphocytic infiltration of dura from right optic nerve; Inflammation and fibrotic changes of right optic nerveIV steroids; Corticosteroids; SurgeryAttache

Insidious Unilateral Vision Loss (Presentation Video)

Poor depth perception and vision ODA 47-year old female with a 4-month history of self-reported shadowy vision and poor depth perception OD. Previous history significant for rheumatoid arthritis, diabetes mellitus and hypothyroidism. Contributory: A 10-year history of smoking and exposure to anti-rheumatic agents.VA: 20/100, improving to 20/60 with pinholeand subsequent decline to 20/200 OD, 20/25 OS; Color plates: 2/8 OD, 7/8 OS; RAPD ODMRILymphocytic infiltration of dura from right optic nerve; Inflammation and fibrotic changes of right optic nerveIV steroids; Corticosteroids; SurgeryAttache

Nivolumab-associated anti-MOG antibody positive Optic Neuritis

Nivolumab has been associated with neurotoxicity. We present a case of MOG-antibody optic neuritis associated with Nivolumab use

Progressive Non-Arteritic Optic Neuropathy As The First Presentation Of Anti-Phospholipid Antibody Syndrome

"To report the clinical presentation and visual outcomes of non-arteritic anterior ischemic optic neuropathy (NAION) with antiphospholipid antibody syndrome (APS).

NAION, BRAO, Tumor or All! (.pdf)

Capillary hemangiomas of the optic disc are vascular hamartomas that may rarely arise from the optic nerve

Bilateral Vision Loss Due to Chiasmal Neuropathy Secondary to Muslinoma (.pdf)

Intracranial aneurysms are surgically managed by microsurgical clipping of the aneurysm neck, endovascular coiling of the aneurysm sac or balloon occlusion of the parent vessel. Cases with broad-based aneurysms may not be amenable to these techniques. Microsurgical wrapping of the aneurysm wall with muslin may be applied

Homonymous Ganglion Cell Layer Thinning Following Temporal Lobectomy Demonstrating Retrograde Transsynaptic Retinal Degeneration in an Adult Patient with Refractory Seizures (.pdf)

Optical coherence tomography (OCT) is a non-invasive imaging technique which provides transpupillarily cross-sectional scans of the retina and the optic disc. With the improvement of the resolution of optical coherence tomography, the ganglion cell complex (GCC) has also become routinely accessible in the clinic. Retrograde trans-synaptic degeneration of retinal GCC may result from postsynaptic lesions of the visual pathway

Pembrolizumab-Related Panuveitis/Choroiditis (.pdf)

"There have been several documented cases of Vogt-Koyanagi-Harada (VKH) like symptoms associated with interferon-alpha treatment in chronic hepatitis C patient. There has also been at least two reports of similar presentations with the use of ipilimumab, another monoclonal antibody used in the treatment of melanoma. We present a case of bilateral optic disc swelling and panuveitis with choroiditis and multifocal serous retinal detachments in a patient being treated with Pembrolizumab and Pegylated interferon alfa-2b for metastatic melanoma.