243 research outputs found

    Cryogenic Calibration Setup for Broadband Complex Impedance Measurements

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    Reflection measurements give access to the complex impedance of a material on a wide frequency range. This is of interest to study the dynamical properties of various materials, for instance disordered superconductors. However reflection measurements made at cryogenic temperature suffer from the difficulty to reliably subtract the circuit contribution. Here we report on the design and first tests of a setup able to precisely calibrate in situ the sample reflection, at 4.2 K and up to 2 GHz, by switching and measuring, during the same cool down, the sample and three calibration standards.Comment: (6 pages, 6 figures

    Pathogenesis, risk factors and therapeutic options for autoimmune haemolytic anaemia in the post-transplant setting

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    Autoimmune haemolytic anaemia (AIHA) is a rare complication of allogeneic haematopoietic stem cell transplantation (HSCT), observed with an incidence of 1–5%. Paediatric age, diagnosis of non-malignant disease, lympho-depleting agents in the conditioning regimen, use of unrelated donor, graft versus host disease and infections have been associated with a higher risk of AIHA post HSCT. Post-HSCT AIHA is associated with high mortality and morbidity, and it is often very difficult to treat. Steroids and rituximab are used with a response rate around 30–50%. These and other therapeutic strategies are mainly derived from data on primary AIHA, although response rates in post-HSCT AIHA have been generally lower. Here we review the currently available data on risk factors and therapeutic options. There is a need for prospective studies in post-HSCT AIHA to guide clinicians in managing these complex patients

    ARTICLE Photon-assisted tunnelling with nonclassical light

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    International audienceAmong the most exciting recent advances in the field of superconducting quantum circuits is the ability to coherently couple microwave photons in low-loss cavities to quantum electronic conductors. These hybrid quantum systems hold great promise for quantum information-processing applications; even more strikingly, they enable exploration of new physical regimes. Here we study theoretically the new physics emerging when a quantum electronic conductor is exposed to nonclassical microwaves (for example, squeezed states, Fock states). We study this interplay in the experimentally relevant situation where a superconducting microwave cavity is coupled to a conductor in the tunnelling regime. We find that the conductor acts as a nontrivial probe of the microwave state: the emission and absorption of photons by the conductor is characterized by a nonpositive definite quasi-probability distribution, which is related to the Glauber-Sudarshan P-function of quantum optics. These negative quasi-probabilities have a direct influence on the conductance of the conductor

    Noninvasiveness and time symmetry of weak measurements

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    Measurements in classical and quantum physics are described in fundamentally different ways. Nevertheless, one can formally define similar measurement procedures with respect to the disturbance they cause. Obviously, strong measurements, both classical and quantum, are invasive -- they disturb the measured system. We show that it is possible to define general weak measurements, which are noninvasive: the disturbance becomes negligible as the measurement strength goes to zero. Classical intuition suggests that noninvasive measurements should be time symmetric (if the system dynamics is reversible) and we confirm that correlations are time-reversal symmetric in the classical case. However, quantum weak measurements -- defined analogously to their classical counterparts -- can be noninvasive but not time symmetric. We present a simple example of measurements on a two-level system which violates time symmetry and propose an experiment with quantum dots to measure the time-symmetry violation in a third-order current correlation function.Comment: 19 pages, 5 figures, more information at http://www.fuw.edu.pl/~abednorz/tasym

    Quantum capacitance: a microscopic derivation

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    We start from microscopic approach to many body physics and show the analytical steps and approximations required to arrive at the concept of quantum capacitance. These approximations are valid only in the semi-classical limit and the quantum capacitance in that case is determined by Lindhard function. The effective capacitance is the geometrical capacitance and the quantum capacitance in series, and this too is established starting from a microscopic theory.Comment: 7 fig

    Using GPS tracking to determine movement patterns and foraging habitat selection of the Common Barn-owl (Tyto alba)

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    Se realizó por primera vez el seguimiento con GPS de un individuo de Lechuza de Campanario (Tyto alba) para evaluar el uso de un dispositivo de uso comercial económico diseñado para el seguimiento de mascotas y el uso del seguimiento con GPS como técnica para determinar los patrones de movimiento y la selección de hábitat de alimentación. El dispositivo original fue reacondicionado y colocado en un macho adulto. El dispositivo registró 12501 puntos georreferenciados durante ocho noches consecutivas. El área de acción, estimada a través del mínimo polígono convexo, fue de 1746 ha. Los recorridos obtenidos permitieron la identificación de tres patrones de movimiento que pueden ser atribuidos a diferentes comportamientos: tortuoso, lineal y puntual, correspondientes a caza, traslado y descanso, respectivamente. La superposición de los recorridos con un mapa de la cobertura de distintos usos de la tierra reveló que la lechuza seleccionó para cazar áreas con vegetación (excepto donde había ganado porcino) y áreas denudadas con ganado porcino. El uso de esta técnica representa un avance para los estudios comportamentales en esta especie.For the first time a Common Barn-owl (Tyto alba) individual was tracked using a GPS technology to evaluate the use of a commercial and economic GPS pet tracker device, and to test GPS tracking as a technique for determining movement patterns and foraging habitat selection. A GPS pet tracker device was removed from its plastic frame and attached to the back of an adult male. The device recorded during eight consecutive nights a total of 12501 waypoints. The home range, estimated as the minimum convex polygon, was 1746 ha. Tracks obtained allowed the identification of three movement patterns that could be attributed to different behaviours: meandering, linear and point, corresponding to hunting, straight-lined flights and roosting, respectively. The overlap of tracks with a land cover map revealed that the owl selected vegetated areas (except where pigs were present) and barren areas with pigs for hunting. The use of this technique represents an improvement for behavioural studies of this species

    MIK2 is a candidate gene of the S-locus for sporophytic self-incompatibility in chicory (Cichorium intybus, Asteraceae)

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    The Cichorium genus offers a unique opportunity to study the sporophytic self-incompatibility (SSI) system, being composed of species characterized by highly efficient self-incompatibility (e.g., C. intybus) and complete self-compatibility (e.g., C. endivia). To this end, the chicory genome was used to map seven previously identified SSI locus-associated markers. The region containing the S-locus was therefore restricted to an similar to 4 M bp window on chromosome 5. Among the genes predicted in this region, MDIS1 INTERACTING RECEPTOR LIKE KINASE 2 (ciMIK2) was particularly promising as a candidate for SSI. Its ortholog in Arabidopsis (atMIK2) is involved in pollen-stigma recognition reactions, and its protein structure is similar to that of S-receptor kinase (SRK), a key component of the SSI system in the Brassica genus. The amplification and sequencing of MIK2 in chicory and endive accessions revealed two contrasting scenarios. In C. endivia, MIK2 was fully conserved even when comparing different botanical varieties (i.e., smooth and curly endive). In C. intybus, 387 polymorphic positions and 3 INDELs were identified when comparing accessions of different biotypes all belonging to the same botanical variety (i.e., radicchio). The polymorphism distribution throughout the gene was uneven, with hypervariable domains preferentially localized in the LRR-rich extracellular region, putatively identified as the receptor domain. The gene was hypothesized to be under positive selection, as the nonsynonymous mutations were more than double the synonymous ones (dN/dS = 2.17). An analogous situation was observed when analyzing the first 500 bp of the MIK2 promoter: no SNPs were observed among the endive samples, whereas 44 SNPs and 6 INDELs were detected among the chicory samples. Further analyses are needed to confirm the role of MIK2 in SSI and to demonstrate whether the 23 species-specific nonsynonymous SNPs in the CDS and/or the species-specific 10 bp-INDEL found in a CCAAT box region of the promoter are responsible for the contrasting sexual behaviors of chicory and endive
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