10,737 research outputs found

    Tests for High Dimensional Generalized Linear Models

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    We consider testing regression coefficients in high dimensional generalized linear models. An investigation of the test of Goeman et al. (2011) is conducted, which reveals that if the inverse of the link function is unbounded, the high dimensionality in the covariates can impose adverse impacts on the power of the test. We propose a test formation which can avoid the adverse impact of the high dimensionality. When the inverse of the link function is bounded such as the logistic or probit regression, the proposed test is as good as Goeman et al. (2011)'s test. The proposed tests provide p-values for testing significance for gene-sets as demonstrated in a case study on an acute lymphoblastic leukemia dataset.Comment: The research paper was stole by someone last November and illegally submitted to arXiv by a person named gong zi jiang nan. We have asked arXiv to withdraw the unfinished paper [arXiv:1311.4043] and it was removed last December. We have collected enough evidences to identify the person and Peking University has begun to investigate the plagiarize

    Automatic landmark annotation and dense correspondence registration for 3D human facial images

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    Dense surface registration of three-dimensional (3D) human facial images holds great potential for studies of human trait diversity, disease genetics, and forensics. Non-rigid registration is particularly useful for establishing dense anatomical correspondences between faces. Here we describe a novel non-rigid registration method for fully automatic 3D facial image mapping. This method comprises two steps: first, seventeen facial landmarks are automatically annotated, mainly via PCA-based feature recognition following 3D-to-2D data transformation. Second, an efficient thin-plate spline (TPS) protocol is used to establish the dense anatomical correspondence between facial images, under the guidance of the predefined landmarks. We demonstrate that this method is robust and highly accurate, even for different ethnicities. The average face is calculated for individuals of Han Chinese and Uyghur origins. While fully automatic and computationally efficient, this method enables high-throughput analysis of human facial feature variation.Comment: 33 pages, 6 figures, 1 tabl

    Transmission of doughnut light through a bull's eye structure

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    We experimentally investigate the extraordinary optical transmission of doughnut light through a bull's eye structure. Since the intensity is vanished in the center of the beam, almost all the energy reaches the circular corrugations (not on the hole), excite surface plasmons which propagate through the hole and reradiate photons. The transmitted energy is about 57 times of the input energy on the hole area. It is also interesting that the transmitted light has a similar spatial shape with the input light although the diameter of the hole is much smaller than the wavelength of light.Comment: 3 pages,4 figure
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