9 research outputs found
REVIEW: Mammalian fertilization as a biological machine: a working model for adhesion and fusion of sperm and oocyte
Building comparative gene expression databases for the mouse preimplantation embryo using a pipeline approach to UniGene
Acetylcholine receptor turnover in mice with passively transferred myasthenia gravis. I. Receptor degradation.
Integridade das membranas plasmática, nuclear e mitocondrial de espermatozóides ovinos criopreservados com etileno glicol
Myasthenia gravis: further electrophysiological and ultrastructural analysis of transmission failure in the mouse passive transfer model.
Estimating Species Abundance in a Northern Temperate Forest Using Spectral Mixture Analysis
Experimental autoimmune myasthenia gravis.
Injection of animals with purified acetylcholine receptor in complete Freund's adjuvant causes development of antibodies which crossreact with receptors in muscle. The crossreacting antibodies impair neuromuscular transmission. Animals with experimental autoimmune myasthenia gravis (EAMG) are excellent models for studying the complex mechanisms by which the autoimmune response to receptor in myasthenia gravis causes muscle weakness. This review first briefly describes the discovery of EAMG. Then, to provide the necessary perspective, receptor structure and function and properties of anti-receptor antibodies are discussed, followed by a brief review of the pathological mechanisms in EAMG
