37,005 research outputs found
Attitudes Toward Failure in Capstone Design Projects
While working in industry during the 1980s and 1990s, project failures were to be avoided at all costs. For engineers in the medical device industry, these failures could be in the form of: 1) an idea for a new product or feature that eventually failed due to technical infeasibility, regulatory hurdles, lack of market interest, or difficulty in manufacturing; 2) a prototype that did not function as required; or 3) an animal or human clinical study that yielded poor results. They typically resulted in significant project delays, wasted time and money, and lost revenues, and often led to lower raises, fewer promotion opportunities, and damaged reputations
Entrepreneurship in Capstone Design: Has the Pendulum Swung Too Far?
The author supports entrepreneurial education for all interested students, but not at the expense of design education. He thinks we should develop business literacy among all of our students to prepare them for work in start-ups and established medical device companies, and provide opportunities for interested students to add entrepreneurial literacy to better prepare them to create new companies, either upon graduation or later in their careers. Capstone design courses should focus on helping students develop solid design skills and providing opportunities to apply the analytical tools learned in previous courses. Students should be encouraged, not required, to consider commercializing the results of their capstone projects, and interested students should be provided with support for doing so
Will the Real Designer Please Stand Up? [Senior Design]
In the 1950s and 1960s, there was a popular television show called To Tell the Truth, on which three contestants claimed to be a person with an unusual occupation or distinction. Two of them were impostors, and the other was telling the truth. Four panelists asked the contestants questions to determine who was being truthful. After each panelist chose the contestant he or she thought was telling the truth, the host would ask Will the real _____ please stand up? To create drama, each contestant would rise at different times and then sit, leaving the contestant with the unusual occupation or distinction standing
Middle Atmosphere Electrodynamics (MAE). Middle atmospheric electrodynamics during MAP
The recent revival and strong motivation for research in middle atmospheric electrodynamics can be attributed, in large part, to the discovery of large (V/m) electric fields within the lower mesosphere during the decade prior to MAP. Subsequent rocket soundings appeared to verify the preliminary findings. During the MAP era, more sophisticated techniques have been employed to obtain measurements which respond positively to criticisms of earlier results, and which provide more insight regarding the character of the fields. The occurrence of mesospheric V/m electric fields now seems to require the presence of aerosols, of local winds and related dynamics, and of an atmospheric electrical conductivity less than 10(-10)S/m. Furthermore, new theoretical ideas describing the origin of the V/m fields are consistent with the measurements. The current status of results regarding V/m fields in the middle atmosphere is reviewed in light of the more widely accepted electric field structure for this region from rocket, balloon and modeling results
Silicon ions below 100 km: A case for SiO2(+)
Silicon ions are normally detected at altitudes above 100 km and within sporadic E layers. Traces have rarely been observed within the more permanent metallic layer near 93 km. This is surprising since silicon is an important constituent of chondritic meteorites, which ablate material in this region to provide a primary source of the metallic species observed there. Evidence is presented that Si(+)ions form SiO2(+) at the lower altitudes, and exist in this ionic state prior to recombination. A rocket launched from El Arenosillo, Spain on 3 July 1972, at 0743 LMT, during the predicted period of the Beta Taurids meteor shower, passed through a continuous belt of metallic ions that began near 85 km, ended near 115 km, and exhibited an order of magnitude increase in the form of a layer near 114 km. Si(+)was measured in and below the ledge down to 103 km. It showed a rapid decrease below this height. Radiative association is offered as a primary mechanism for SiO2(+) production
Test Bed Concentrator (TBC)
A point focussing concentrator design adapted from an existing communications antenna for use in a solar test bed application is described. The structure design, configured for use with JPL's spherical radius mirror panels, made no attempt toward optimization. The key objectives of stiffness, pointing accuracy, and timely delivery were exceeded. The system weight is approximately 16,000 Kg (36,000 lbs) and has a calculated 1 sigma system error of 0.03 degrees
Q-learning with censored data
We develop methodology for a multistage decision problem with flexible number
of stages in which the rewards are survival times that are subject to
censoring. We present a novel Q-learning algorithm that is adjusted for
censored data and allows a flexible number of stages. We provide finite sample
bounds on the generalization error of the policy learned by the algorithm, and
show that when the optimal Q-function belongs to the approximation space, the
expected survival time for policies obtained by the algorithm converges to that
of the optimal policy. We simulate a multistage clinical trial with flexible
number of stages and apply the proposed censored-Q-learning algorithm to find
individualized treatment regimens. The methodology presented in this paper has
implications in the design of personalized medicine trials in cancer and in
other life-threatening diseases.Comment: Published in at http://dx.doi.org/10.1214/12-AOS968 the Annals of
Statistics (http://www.imstat.org/aos/) by the Institute of Mathematical
Statistics (http://www.imstat.org
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