56 research outputs found

    A formal adversarial perspective: Secure and efficient electronic health records collection scheme for multi‐records datasets

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    The collection of private health data without compromising privacy is an imperative aspect of privacy‐aware data collection mechanisms. Privacy‐preserved data collection is achieved by anonymizing private data before its transmission from data holders to data collectors. Though there exist ample literature on private data collection for 1:1 (single record of a data holder) datasets, collecting multi‐records (multiple records of a data holder) datasets (referred to as 1:M datasets) has not received due attention from the research community. Therefore, the current studies experience serious privacy breaches in 1:M dataset thereby limiting their application in secure healthcare applications and systems. In this work, we have formally classified main privacy disclosures on these data collection mechanisms and proposed an improved privacy scheme, namely, horizontal sliced permuted permutation (H‐SPP) for 1:M datasets. It uses the composite slicing and anatomy‐based approach to protect against the privacy violations like identity, attribute, and membership disclosures. Moreover, we perform formal modeling of the proposed scheme using high‐level Petri nets (HLPN) and show that it effectively prevents the identified external and internal privacy attacks. Experimental results show that H‐SPP provides robust privacy for health data with high performance.</p

    Cost-effectiveness analysis of breast cancer control interventions in peru

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    Contains fulltext : 125263.pdf (publisher's version ) (Open Access)OBJECTIVES: In Peru, a country with constrained health resources, breast cancer control is characterized by late stage treatment and poor survival. To support breast cancer control in Peru, this study aims to determine the cost-effectiveness of different breast cancer control interventions relevant for the Peruvian context. METHODS: We performed a cost-effectiveness analysis (CEA) according to WHO-CHOICE guidelines, from a healthcare perspective. Different screening, early detection, palliative, and treatment interventions were evaluated using mathematical modeling. Effectiveness estimates were based on observational studies, modeling, and on information from Instituto Nacional de Enfermedades Neoplasicas (INEN). Resource utilizations and unit costs were based on estimates from INEN and observational studies. Cost-effectiveness estimates are in 2012 United States dollars (US)perdisabilityadjustedlifeyear(DALY)averted.RESULTS:ThecurrentbreastcancerprograminPeru() per disability adjusted life year (DALY) averted. RESULTS: The current breast cancer program in Peru (8,426 per DALY averted) could be improved through implementing triennial or biennial screening strategies. These strategies seem the most cost-effective in Peru, particularly when mobile mammography is applied (from 4,125perDALYaverted),orwhenbothCBEscreeningandmammographyscreeningarecombined(from4,125 per DALY averted), or when both CBE screening and mammography screening are combined (from 4,239 per DALY averted). Triennially, these interventions costs between 63millionand63 million and 72 million per year. Late stage treatment, trastuzumab therapy and annual screening strategies are the least cost-effective. CONCLUSIONS: Our analysis suggests that breast cancer control in Peru should be oriented towards early detection through combining fixed and mobile mammography screening (age 45-69) triennially. However, a phased introduction of triennial CBE screening (age 40-69) with upfront FNA in non-urban settings, and both CBE (age 40-49) and fixed mammography screening (age 50-69) in urban settings, seems a more feasible option and is also cost-effective. The implementation of this intervention is only meaningful if awareness raising, diagnostic, referral, treatment and basic palliative services are simultaneously improved, and if financial and organizational barriers to these services are reduced
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