Improved maximum likelihood estimators in a heteroskedastic errors-in-variables model

This paper develops a bias correction scheme for a multivariate heteroskedastic errors-in-variables model. The applicability of this model is justified in areas such as astrophysics, epidemiology and analytical chemistry, where the variables are subject to measurement errors and the variances vary with the observations. We conduct Monte Carlo simulations to investigate the performance of the corrected estimators. The numerical results show that the bias correction scheme yields nearly unbiased estimates. We also give an application to a real data set.Comment: 12 pages. Statistical Paper

How manipulating task constraints in small-sided and conditioned games shapes emergence of individual and collective tactical behaviours in football: A systematic review

Background: Small-Sided and Conditioned Games are characterised by modifications of field dimensions, number of players, rules of the game, manipulations used to shape the key task constraints that performers need to satisfy in practice. Evidence has already demonstrated the importance of designing practice to enhance understanding of tactical behaviours in football, but there is a lack of information about how coaches can manipulate task constraints to support tactical learning. Objective: To investigate which task constraints have been most often manipulated in studies of SSCGs; and what impact each manipulation had on emerging tactical behaviours, technical–tactical actions, and positional relationships between players. Methods: PubMed, Web of Science, Scielo, and Academic Google databases were searched for relevant reports without time limits. The criteria adopted for inclusion were: a) studies performed with football players; b) studies that included SSCGs as an evaluation method; c) studies that investigated tactical behaviours in SSCGs; and d), articles in English and Portuguese. Results: The electronic database search included 24 articles in the review. Of these, five manipulated field dimensions, six manipulated number of players involved, five manipulated field dimensions and number of players, five used different scoring targets, two altered the number of players and scoring target, and one manipulated the number of players, field dimension, and scoring target. Conclusion: Among the task constraints analyzed in this systematic review, manipulation of number of players and playing field dimensions concomitantly occurred most frequentl

How manipulating task constraints in small-sided and conditioned games shapes emergence of individual and collective tactical behaviours in football: A systematic review

Background: Small-Sided and Conditioned Games are characterised by modifications of field dimensions, number of players, rules of the game, manipulations used to shape the key task constraints that performers need to satisfy in practice. Evidence has already demonstrated the importance of designing practice to enhance understanding of tactical behaviours in football, but there is a lack of information about how coaches can manipulate task constraints to support tactical learning. Objective: To investigate which task constraints have been most often manipulated in studies of SSCGs; and what impact each manipulation had on emerging tactical behaviours, technical–tactical actions, and positional relationships between players. Methods: PubMed, Web of Science, Scielo, and Academic Google databases were searched for relevant reports without time limits. The criteria adopted for inclusion were: a) studies performed with football players; b) studies that included SSCGs as an evaluation method; c) studies that investigated tactical behaviours in SSCGs; and d), articles in English and Portuguese. Results: The electronic database search included 24 articles in the review. Of these, five manipulated field dimensions, six manipulated number of players involved, five manipulated field dimensions and number of players, five used different scoring targets, two altered the number of players and scoring target, and one manipulated the number of players, field dimension, and scoring target. Conclusion: Among the task constraints analyzed in this systematic review, manipulation of number of players and playing field dimensions concomitantly occurred most frequentl

Gray Matter Changes in Parkinson's and Alzheimer's Disease and Relation to Cognition

Purpose of Review We summarize structural (s)MRI findings of gray matter (GM) atrophy related to cognitive impairment in Alzheimer's disease (AD) and Parkinson's disease (PD) in light of new analytical approaches and recent longitudinal studies results. Recent Findings The hippocampus-to-cortex ratio seems to be the best sMRI biomarker to discriminate between various AD subtypes, following the spatial distribution of tau pathology, and predict rate of cognitive decline. PD is clinically far more variable than AD, with heterogeneous underlying brain pathology. Novel multivariate approaches have been used to describe patterns of early subcortical and cortical changes that relate to more malignant courses of PD. New emerging analytical approaches that combine structural MRI data with clinical and other biomarker outcomes hold promise for detecting specific GM changes in the early stages of PD and preclinical AD that may predict mild cognitive impairment and dementia conversion