16 research outputs found
Depleting extracellular vesicles from fetal bovine serum alters proliferation and differentiation of skeletal muscle cells in vitro
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Transplantation of allogeneic PW1\u3csup\u3epos\u3c/sup\u3e/Pax7\u3csup\u3eneg\u3c/sup\u3e interstitial cells enhance endogenous repair of injured porcine skeletal muscle
No full text\u3cp\u3eSkeletal muscle-derived PW1\u3csup\u3epos\u3c/sup\u3e/Pax7\u3csup\u3eneg\u3c/sup\u3e interstitial cells (PICs) express and secrete a multitude of proregenerative growth factors and cytokines. Utilizing a porcine preclinical skeletal muscle injury model, delivery of allogeneic porcine PICs (pPICs) significantly improved and accelerated myofiber regeneration and neocapillarization, compared with saline vehicle control-treated muscles. Allogeneic pPICs did not contribute to new myofibers or capillaries and were eliminated by the host immune system. In conclusion, allogeneic pPIC transplantation stimulated the endogenous stem cell pool to bring about enhanced autologous skeletal muscle repair and regeneration. This allogeneic cell approach is considered a cost-effective, easy to apply, and readily available regenerative therapeutic strategy.\u3c/p\u3
β-Adrenergic receptor stimulation induces endoplasmic reticulum stress in adult cardiac myocytes: role in apoptosis
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A significant sex - but not elective cesarean section - Effect on mother-to-child transmission of hepatitis C virus infection
No full textInhibition of Angiotensin-Converting Enzyme Reduces Susceptibility of Hypertrophied Rat Myocardium to Ventricular Fibrillation
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