86 research outputs found

    嶺南大學實測圖

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    此版為黑底白字的複印本,全書共27頁。內容為廣州嶺南大學的手繪地圖,地圖分成25頁。https://commons.ln.edu.hk/lingnan_history_bks/1041/thumbnail.jp

    Core Planar Cell Polarity Genes VANGL1 and VANGL2 in Predisposition to Congenital Vertebral Malformations

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    Congenital scoliosis (CS) is the most common congenital spinal disorder caused by congenital vertebral malformations (CVMs), influenced by genetic and environmental factors and exhibiting diverse clinical presentations. Here, we identified the critical roles of Vangl1 and Vangl2, two core components in the Wnt/planar cell polarity (Wnt/PCP) signaling pathway, in vertebral development and in predisposition to CVMs in CS patients. We found that in Vangl mutant mouse models, the CVMs present in a Vangl gene dose- and gestational hypoxia-dependent manner. Our studies reveal a complex etiology of CS and its association with Wnt/PCP signaling

    A Comparative Study of the Simulation Accuracy and Efficiency for the Urban Wind Environment Based on CFD Plug-Ins Integrated into Architectural Design Platforms

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    The deterioration of the urban environment is a problem which has captured the attention of governmental departments and researchers, who are committed to improving the urban environment from the perspective of optimizing urban morphology. Although many researchers have applied computational fluid dynamics (CFD) plug-ins to study the problems of urban ventilation and pollutant accumulation, studies on the reliability and simulation accuracy verification of CFD plug-ins are currently scarce. Therefore, we used three CFD plug-ins based on different architectural design platforms to evaluate and compare their operation difficulty, simulation accuracy, and efficiency through the analysis of the simulation results of urban ventilation. This study complements the reliability validation of CFD plug-in simulations and guides urban planners and architects in the selection and application of CFD plug-ins. The results show that the CFD plug-in generally underestimates the wind speed at the pedestrian level and the prediction accuracy is poor in the wake area of obstacles, especially with the GH_Wind plug-in. Under the 0° inflow direction, the simulation results of the Butterfly plug-in were the most consistent with the experimental values. When the inflow direction increased to 22.5° and 45°, the Autodesk CFD showed the best simulation accuracy. Overall, Autodesk CFD achieves a balance between simulation accuracy and speed in urban airflow simulation

    Experimental study on the corrosion characteristics of steel bars in concrete considering the effects of multiple factors

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    In this paper, twenty reinforced concrete specimens were designed for accelerated corrosion test, and a systematic study was conducted to investigate the effects of water-cement ratio, thickness of concrete cover, and spacing and quantity of steel bars on the corrosion characteristics of steel bars. The results showed that the mass loss of steel bars approximately increased with the water-cement ratio and decreased with an increase in the thickness of concrete cover. As the spacing between the steel bars in lower layer of the specimens increased, the mass loss of the steel bars in lower layer approximately showed an increasing trend. When there were more than two steel bars arranged in lower layer of the specimens, the mass loss of the middle steel bars was smaller than that of the steel bars located in the corner areas on both sides. The probability distribution type of the corrosion depth was mainly normal distribution, and the influence of water-cement ratio, thickness of concrete cover, and spacing and quantity of steel bars in lower layer of the specimens on the probability distribution was not obvious. The probability distribution type of the width of corrosion-induced cracks was mainly exponential distribution, and the influence of the spacing and quantity of steel bars in lower layer on the probability distribution was not obvious. When the water-cement ratio was large, the width of corrosion-induced cracks was less discrete from its mean value. With the increase of the quantity of steel bars in lower layer, the shape of the probability distribution curve of the width of corrosion-induced cracks tended to be flat. There was a good positive linear relationship between the mass loss of steel bars and the average width of corrosion-induced cracks, and the influence of water-cement ratio and the spacing between the steel bars in lower layer on this linear relationship was irregular. A good positive linear relationship between the maximum width of corrosion-induced cracks and the average corrosion depth of steel bars was established, which was irregularly affected by the water-cement ratio and the spacing between the steel bars in lower layer

    Spatiotemporal Changes in The Urban Landscape Pattern and Driving Forces of LUCC Characteristics in The Urban Agglomeration on The Northern Slope of The Tianshan Mountains from 1995 to 2018

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    Analyses of landscape patterns, analyses of land-use/land-cover evolution characteristics, and a driving force analysis during the expansion of urban agglomerations can assist urban agglomerations in solving ecological and environmental problems; moreover, these tools can provide a reference for urban land-use structure optimization and urban landscape planning. In this study, the rapid urbanization and urban agglomeration of small- and medium-sized cities were evaluated; specifically, the urban agglomeration of the northern slopes of the Tianshan Mountains (UANSTM) was assessed. Using multi-period (1995, 2000, 2005, 2010, 2015, 2018) land-use data and statistical yearbook data, we calculated the landscape index and comprehensive land-use degree index using the Moran index and geographic probe methods. We studied the expansion patterns and spatial distribution patterns of urban land and quantitatively explored the influence mechanisms of natural and socioeconomic factors on the degree of land use to clarify the characteristics and driving forces of land-use evolution. The results show the following: the area of urban land continued to increase between 1995 and 2018; the dominance of the landscape indexes within each time period changed with urban development; and intra-urban landscape heterogeneity is gradually increasing. In terms of the spatial and temporal distribution of the degree of land use, the expansion of urban agglomeration is centered on the city of Urumqi, spreading towards the cities of Changji and Shihezi; the rest of the counties and cities are fast urban-expansion zones. Under the influence of multiple source factors, the expansion of the UANSTM depends on the distribution of oases, which is mainly influenced by the distribution of vegetation and the density of the river network and can only rely on the ecological carrying capacity of oases for production and life. The results of the study can provide a basis for decision-making processes surrounding the future layout of the UANSTM ecological environment
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